Trip from Presidio, TX to Houston, TX
Drive Time
10h 25m
Distance
659.3 mi
Route Type
Long-distance drive
Overnight routeTrip Overview
The drive from Presidio, TX to Houston, TX covers 659.3 miles and takes about 10h 25m behind the wheel. It usually feels better as a 2-day road trip than as one long push.
The route leans on North Erma Avenue, US 67, Highway 67 for much of the mileage, and the overall profile is long-distance drive. At current regular gas prices, budget about $98.09 one way before food or hotel costs.
Trip Pace
Best split across 2 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
329.7 miles from Presidio, TX
A natural place for your longest stop of the day.
Drive Character
At 659.3 miles and 10h 25m of driving, this is a route where fuel stops, weather, and timing matter more than any single turn. The main roads are North Erma Avenue and US 67.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| North Erma Avenue | 0 mi | 0m |
| US 67 | 0 mi | 0m |
| Highway 67 | 0 mi | 0m |
| South Highland Street | 0 mi | 0m |
| East San Antonio Street | 0 mi | 0m |
| West Holland Avenue | 0 mi | 0m |
| Highway 90 | 0 mi | 0m |
| South US Higway 67 | 0 mi | 0m |
Step-by-Step Directions
Start on West O'Reilly Street
Turn sharp right onto North Erma Avenue
Keep slight left to continue on US 67 Business
Turn right onto US Highway 67
Keep slight left to continue on US Highway 67
Continue on South Highland Street
Turn right onto East San Antonio Street
Continue on West Holland Avenue
Continue on East US Highway 90
Turn straight onto US Highway 67
Continue on South US Higway 67
Turn right onto Interstate 10 West
Take the ramp straight toward I 10 East: Fort Stockton
Continue straight
Keep slight right
Take the exit slight right toward Frontage Road
Turn straight onto Interstate 10 West
Turn left onto North Loop 1604 West
Take the ramp straight toward Loop 1604 East
Merge slight left onto Anderson Loop
Turn left onto Interstate 10 East
Take the ramp slight left
Merge slight left onto 90th Infantry Division Highway
Continue on I 10 East: Houston, Austin, Waco
Take the exit slight right toward Downtown, Theatre District
Continue on Smith Street
Turn left onto Preston Street
Turn left onto Louisiana Street
Arrive at your destination
When to Leave
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
Consider an overnight stop or starting very early.
Drive Plan
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 145 miles
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 329.7 miles
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 330 miles
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Last hour of driving
Traffic, exits, and arrival timing usually matter more near Houston, TX than in the middle of the route.
Before You Leave
Open the route before leaving Presidio, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.
Trip Strategy
Day 1
Settle into the route from Presidio, TX
Aim for roughly 330 miles and 5.2 hours of wheel time on this day.
Day 2
Finish the approach into Houston, TX
Aim for roughly 330 miles and 5.2 hours of wheel time on this day.
Best Stop Towns on This Route
These towns line up with the pace of this drive and give you clearer places to stop with a purpose.
Late stop town
Coffee and fuel
218 mi into the route
Best for: Coffee, fuel, and an easy first stretch
This is a natural early stop once the first hours of the drive are behind you.
Late stop town
Overnight candidate
435 mi into the route
Best for: Hotel check-in, dinner, and a fresh start
This lines up well with a realistic day-end stop if you are breaking the drive into stages.
Suggested Overnight Stops
Night 1
330 mi · about 5.2h in
A practical overnight split lands near San Antonio, TX after about 330 miles or 5.2 hours of driving.
Travel Advice
Arrival Notes
Seasonal Notes
Stops Along the Way
Halfway Point
Midpoint
About 329.7 mi from Presidio, TX
A short stop after about 145 miles helps settle the day before fatigue starts building.
The midpoint is around 329.7 miles from Presidio, TX, which is a good place for a longer meal and fuel stop.
Overnight split
Hotel stopFor a steadier pace, wrap day one after about 330 miles or 5.2 hours on the road.
These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| regular | $3.78 | $98.09 | $196.18 |
| midgrade | $4.25 | $110.37 | $220.74 |
| premium | $4.59 | $119.17 | $238.33 |
| diesel | $3.99 | $103.65 | $207.29 |
Based on 25.4 MPG average. Estimated CO2 emission: 230.7 kg one way.
Frequently Asked Questions
Next Route Ideas
Explore more options from Presidio, TX or browse trips ending in Houston, TX .
Looking for more statewide routes? Browse TX road trips .
Explore maps and details for Presidio, TX or Houston, TX on MapSof.net.