The drive from Pueblo, CO to Clifton, CO covers 348.2 miles and takes about 6h 27m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 70, Ronald Reagan Highway, John F. Kennedy Memorial Highway for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 224.5 miles on I 70.
At current regular gas prices, budget about $52.46 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
174.1 miles from Pueblo, CO
A natural place for your longest stop of the day
, about 3h 12m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 27m. Total distance: 348.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 27m drive, plan rest stops for pacing.
Drive Character
This is a 6h 27m highway drive covering 348.2 miles, with most of the trip on I 70 and Ronald Reagan Highway. The longest continuous stretch is about 224.5 miles on I 70.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 21 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 70 is the longest continuous segment at about 224.5 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on I 70 and Ronald Reagan Highway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.7 miles in near I 25 / South Freeway.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 15 significant decision points across 348.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.7 miles (I 25 / South Freeway): Merge point - match speed before joining. Lane positioning matters here; at 112.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 112.2 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 15 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
0.7 mi into trip|~1m in|I 25 / South Freeway
Merge onto I 25 / South Freeway
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
7
112.1 mi into trip|~2h 1m in
Take the exit toward US 6 West: 6th Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 209A-B
Toward US 6 West: 6th Avenue
9
112.2 mi into trip|~2h 2m in
Keep slight right at fork toward US 6 West: 6th Avenue, Lakewood
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 209B
Toward US 6 West: 6th Avenue, Lakewood
6
121.3 mi into trip|~2h 14m in
Take the exit toward I 70 West: Grand Junction
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Toward I 70 West: Grand Junction
6
346.5 mi into trip|~6h 23m in|I 70 BUS
Take the exit onto I 70 BUS toward I 70 Business, US 6, US 50: Clifton, Grand Junction, Delta
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 37
Toward I 70 Business, US 6, US 50: Clifton, Gra...
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Pueblo, CO to Clifton, CO, road signs begin pointing toward Lakewood along the way.
Lakewood
112.2 mi in|~2h 2m
Main Roads
Road
Distance
Duration
I 70
224.5 mi
4h 8m
Ronald Reagan Highway
83.8 mi
1h 29m
John F. Kennedy Memorial Highway
12.9 mi
12m
Monument Valley Freeway
8.5 mi
9m
West 6th Avenue Freeway
7.6 mi
9m
South Freeway
6.1 mi
8m
I 70 BUS
1.4 mi
2m
Dinosaur Diamond Prehistoric Highway
0.9 mi
1m
Longest stretch:
I 70
— 224.5 mi, about 4h 8m
Turn-by-Turn Driving Directions
Step-by-step road directions between Pueblo, CO and Clifton, CO.
1
Start on this road
0.2 mi·35 sec·this road
Toward Abriendo Avenue
2
Turn left onto Elm Street
29 ft·6 sec·Elm Street
3
Take the ramp
165 ft·4 sec
4
Keep slight left at fork
0.4 mi·57 sec
5
Merge onto I 25
6.1 mi·8 min·South Freeway
Use the straight lane.
6
Continue on I 25
13 mi·12 min·John F. Kennedy Memorial Highway
Use the straight / slight right lanes.
7
Continue on I 25
23 mi·23 min·Ronald Reagan Highway
Use the straight / slight right lanes.
8
Continue on I 25; US 24
8.5 mi·9 min·Monument Valley Freeway
Use the straight / slight right lanes.
9
Continue on I 25
61 mi·1 hr 5 min·Ronald Reagan Highway
Use the straight / slight right lanes.
10
Take the exit
0.2 mi·23 sec
Exit 209A-BToward US 6 West: 6th AvenueUse the slight right lane.
11
Keep slight right at fork
0.4 mi·53 sec
Exit 209BToward US 6 West: 6th Avenue, LakewoodUse the straight / slight right lanes.
12
Continue on US 6
0.9 mi·1 min·Dinosaur Diamond Prehistoric Highway
13
Keep slight left at fork onto US 6
0.1 mi·10 sec·US 6
Toward US 6
14
Merge onto US 6
7.6 mi·9 min·West 6th Avenue Freeway
Use the straight / slight right lanes.
15
Take the exit
0.7 mi·55 sec
Toward I 70 West: Grand JunctionUse the slight right lane.
16
Merge onto I 70
225 mi·4 hr 8 min·I 70
Use the straight / slight right lanes.
17
Take the exit onto I 70 BUS
1.4 mi·2 min·I 70 BUS
Exit 37Toward I 70 Business, US 6, US 50: Clifton, Grand Junction, Delta
18
Turn sharp left onto US 6
0.2 mi·33 sec·F Road
Use the left lane.
19
Enter roundabout onto US 6
76 ft·1 sec·F Road
20
Continue on US 6
361 ft·10 sec·F Road
21
Arrive at destination
US 6
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 174.1 miles from Pueblo, CO, or about 3h 12m into the drive.
The longest continuous stretch on this route runs about 224.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 77 miles or 1h 24m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 174.1 miles or 3h 12m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 19m
Traffic, exits, and arrival timing usually matter more near Clifton, CO than in the middle of the route.
Before You Leave
+
Open the route before leaving Pueblo, CO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Pueblo, CO
This is one driving day of about 348.2 miles and 6h 27m.
Your first comfortable stop window is around 77 miles from Pueblo, CO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 70 for about 224.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 174.1 mi from Pueblo, CO
· 3h 12m into the drive
The midpoint is around 174.1 miles from Pueblo, CO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before I 70 if your tank is already low. That segment runs about 224.5 miles.
Arriving in Clifton, CO
The final approach into Clifton, CO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Clifton, CO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Colorado National Monument
National Monument
Colorado National Monument preserves one of the grand landscapes of the American West. But this treasure is much more than a monument. Towering monoliths exist within a vast plateau and canyon panoram...
13 mi from route
~33 min detour
$25
near mile 348.2
Beneath a grassy mountain valley in central Colorado lies one of the richest and most diverse fossil deposits in the world. Petrified redwood stumps up to 14 feet wide and thousands of detailed fossil...
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$52.46 one way
$104.93 round trip
$3.83/gal25.4 MPG avg122 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.05
$55.55
$111.09
premium
$4.39
$60.24
$120.47
diesel
$5.61
$76.88
$153.76
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$52
Meals
$25–$50
Total
$77–$102
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 121.8 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $37 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
104.5
1
$36.56
$16.71
Efficient EV
87.1
0
$30.47
$13.93
EV Truck/SUV
139.3
1
$48.75
$22.28
Gas CO2
122 kg
EV CO2
41 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
Pueblo, CO
Morning
in Pueblo on Thursday
Local time
11:02 AM
MDT
Current temp
80°F
Sunny
SW 10 to 20 mph0% chanceLive forecast
Destination
Clifton, CO
Morning
in Clifton on Thursday
Local time
11:02 AM
MDT
Current temp
71°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
9 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 27m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Pueblo, CO to Clifton, CO covers 348.2 miles and takes about 6h 27m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 70, Ronald Reagan Highway, John F. Kennedy Memorial Highway. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 174.1 miles from Pueblo, CO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $52.46 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 15 significant decision points across 348.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.7 miles (I 25 / South Freeway): Merge point - match speed before joining. Lane positioning matters here; at 112.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 112.2 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
On the drive from Pueblo, CO to Clifton, CO, road signs begin pointing toward Lakewood along the way.
Yes. Nearby national parks include Colorado National Monument and Florissant Fossil Beds National Monument.
