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Trip from Saint Charles, MO to Oregon County, MO

Last recalculated Apr 16, 2026

Drive Time

4h 42m

Distance

208.2 mi

335 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$33

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
4h 29m ★
6 AM
4h 42m
8 AM
5h 9m
10 AM
4h 52m
12 PM
4h 49m
3 PM
4h 53m
5 PM
5h 8m
8 PM
4h 34m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in and county seat of St. Charles County, Missouri, United States

Saint Charles, MO

Wikimedia Commons

Downtown Oregon County, MO, MO

Oregon County, MO

Brett Sayles

Trip Overview

The drive from Saint Charles, MO to Oregon County, MO covers 208.2 miles and takes about 4h 42m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on MO 19, Henry Shaw Ozark Corridor, MO 68 for much of the mileage, and the overall profile is mixed drive. The longest uninterrupted segment is about 81.8 miles on MO 19. At current regular gas prices, budget about $32.55 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

104.1 miles from Saint Charles, MO

A natural place for your longest stop of the day , about 2h 5m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 4h 42m. Total distance: 208.2 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

4h 42m drive, comfortable solo distance.

Drive Character

The drive from Saint Charles, MO to Oregon County, MO covers 208.2 miles and takes about 4h 42m, using a mix of highways and local roads.

Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 26 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
MO 19 is the longest continuous segment at about 81.8 miles.

How Hard Is This Drive?

This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.4 miles in near MO 94 / South Fifth Street.

Driving Effort 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 18 significant decision points across 208.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 0.4 miles (MO 94 / South Fifth Street): Lane positioning matters here; at 4.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 4.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.

Critical Maneuvers

5 of 18 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6
0.4 mi into trip | ~1m in | MO 94 / South Fifth Street

Turn left onto MO 94 / South Fifth Street

Lane positioning matters here

Use the straight / right lanes.
8
4.3 mi into trip | ~7m in

Take the exit toward I 270: Chicago, Memphis

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 232 Toward I 270: Chicago, Memphis
7
4.5 mi into trip | ~8m in

Keep slight right at fork toward I 270 South: Memphis

Highway fork - watch signs carefully. Lane positioning matters here

Use the slight right lane. Toward I 270 South: Memphis
7
16 mi into trip | ~22m in

Take the exit toward Dougherty Ferry Road

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Exit 8 Toward Dougherty Ferry Road
6
97.2 mi into trip | ~1h 54m in

Take the exit toward MO 8, MO 68: Saint James

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 195 Toward MO 8, MO 68: Saint James

Main Roads

Road Distance Duration
MO 19 81.8 mi 1h 56m
Henry Shaw Ozark Corridor 76.4 mi 1h 23m
MO 68 22.3 mi 39m
I 270 10.9 mi 13m
North Jefferson Street 4.8 mi 7m
I 70 2.7 mi 3m
Dougherty Ferry Road 2.5 mi 4m
South Fifth Street 1.1 mi 2m
Longest stretch: MO 19 — 81.8 mi, about 1h 56m

Turn-by-Turn Driving Directions

Step-by-step road directions between Saint Charles, MO and Oregon County, MO.

1

Start on North Second Street

0.2 mi · 38 sec · North Second Street
2

Turn right onto Jefferson Street

0.2 mi · 44 sec · Jefferson Street
3

Turn left onto MO 94

1.1 mi · 2 min · South Fifth Street
Use the straight / right lanes.
4

Take the ramp

0.2 mi · 14 sec
Toward I 70 East Use the left / straight lanes.
5

Merge onto I 70

2.7 mi · 3 min · I 70
6

Take the exit

0.2 mi · 12 sec
Exit 232 Toward I 270: Chicago, Memphis Use the slight right lane.
7

Keep slight right at fork

0.4 mi · 33 sec
Toward I 270 South: Memphis Use the slight right lane.
8

Continue on this road

0.1 mi · 10 sec · this road
Exit 232 Toward I 270 South: Memphis
9

Merge onto I 270

11 mi · 13 min · I 270
Use the straight lane.
10

Take the exit

0.3 mi · 28 sec
Exit 8 Toward Dougherty Ferry Road Use the slight right lane.
11

Turn right onto Dougherty Ferry Road

2.5 mi · 4 min · Dougherty Ferry Road
Use the straight lane.
12

Continue on Forest Avenue

1.0 mi · 2 min · Forest Avenue
13

Turn left onto MO 141

0.7 mi · 1 min · MO 141
14

Take the exit

105 ft · 3 sec
15

Turn right onto North Highway Drive

0.1 mi · 14 sec · North Highway Drive
16

Take the ramp

0.2 mi · 13 sec
Toward I 44 West, US 50 West: Rolla
17

Merge onto I 44; US 50

76 mi · 1 hr 23 min · Henry Shaw Ozark Corridor
Use the straight lane.
18

Take the exit

0.1 mi · 17 sec
Exit 195 Toward MO 8, MO 68: Saint James
19

Turn left onto US Historic 66; MO 8; MO 68

4.8 mi · 7 min · North Jefferson Street
20

Turn right onto MO 68

22 mi · 39 min · MO 68
21

Continue on MO 19

56 mi · 1 hr 18 min · MO 19
22

Turn right onto US 60; MO 19

0.8 mi · 1 min · US 60; MO 19
23

Turn left onto MO 19

26 mi · 38 min · MO 19
24

Turn left onto US 160; MO 19

0.6 mi · 57 sec · US 160; MO 19
25

Continue on Tucker Creek Road

0.5 mi · 1 min · Tucker Creek Road
26

Arrive at destination

Tucker Creek Road

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 104.1 miles from Saint Charles, MO, or about 2h 5m into the drive.
The longest continuous stretch on this route runs about 81.8 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 46 miles or 58m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 104.1 miles or 2h 5m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 46m

Traffic, exits, and arrival timing usually matter more near Oregon County, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Saint Charles, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Saint Charles, MO

This is one driving day of about 208.2 miles and 4h 42m.

Your first comfortable stop window is around 46 miles from Saint Charles, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MO 19 for about 81.8 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 104.1 mi from Saint Charles, MO · 2h 5m into the drive

Downtown Steelville, MO, MO

Mid-route town

Meal stop

Steelville, MO

104 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Wildwood, MO

Fuel and coffee

A short stop after about 46 miles helps settle the day before fatigue starts building.

Cuba, MO

Meal break

The midpoint is around 104.1 miles from Saint Charles, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before MO 19 if your tank is already low. That segment runs about 81.8 miles.

Arriving in Oregon County, MO

The final approach into Oregon County, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Oregon County, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$32.55 one way

$65.10 round trip

$3.97/gal 25.4 MPG avg 73 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $35.74 $71.48
premium $4.89 $40.07 $80.13
diesel $5.61 $45.97 $91.94

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$33

Meals

$25–$50

Total

$58–$83

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 72.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $22 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 62.5 0 $21.86 $9.99
Efficient EV 52.1 0 $18.22 $8.33
EV Truck/SUV 83.3 1 $29.15 $13.32

Gas CO2

73 kg

EV CO2

24 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Saint Charles, MO

Evening in Saint Charles on Thursday

Local time

5:53 PM

CDT

Current temp

57°F

Unavailable

Live forecast

Destination

Oregon County, MO

Evening in Oregon County on Thursday

Local time

5:53 PM

CDT

Current temp

45°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

12 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 42m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Saint Charles, MO to Oregon County, MO covers 208.2 miles and takes about 4h 42m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are MO 19, Henry Shaw Ozark Corridor, MO 68. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 104.1 miles from Saint Charles, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $32.55 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 18 significant decision points across 208.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.4 miles (MO 94 / South Fifth Street): Lane positioning matters here; at 4.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 4.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.
The route from Saint Charles, MO to Oregon County, MO does not surface many named destination signs beyond the main corridor.

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