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Trip from Saint Martin, MS to Greenville, MS

Last recalculated Apr 16, 2026

Drive Time

5h 53m

Distance

282.3 mi

454 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$43

one way

Best Time to Leave

Save up to 39 min
4 AM
5h 41m ★
6 AM
5h 54m
8 AM
6h 20m
10 AM
6h 3m
12 PM
6h 0m
3 PM
6h 4m
5 PM
6h 18m
8 PM
5h 46m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Saint Martin, MS, MS

Saint Martin, MS

Jean-Paul Wettstein

Downtown Greenville, MS, MS

Greenville, MS

Wikimedia Commons

Trip Overview

The drive from Saint Martin, MS to Greenville, MS covers 282.3 miles and takes about 5h 53m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on US 49, US 49W, Medgar Evers Boulevard for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 140.6 miles on US 49. At current regular gas prices, budget about $42.63 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

141.2 miles from Saint Martin, MS

A natural place for your longest stop of the day , about 2h 56m into the drive .

Drive Character

This is a 5h 53m highway drive covering 282.3 miles, with most of the trip on US 49 and US 49W. The longest continuous stretch is about 140.6 miles on US 49.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 33 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 49 is the longest continuous segment at about 140.6 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on US 49 and US 49W. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.4 miles in near Lemoyne Boulevard.

Route Complexity 10/10

High effort - long or complex enough to need steady focus all day

This is a demanding drive. With 23 significant decision points across 282.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 0.4 miles (Lemoyne Boulevard): Navigation decision point; at 24.9 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.3 miles (US 49): Merge point - match speed before joining. Lane positioning matters here.

Critical Maneuvers

5 of 23 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

5
0.4 mi into trip | ~1m in | Lemoyne Boulevard

At end of road, turn left onto Lemoyne Boulevard

Navigation decision point

6
24.9 mi into trip | ~32m in

Keep slight right at fork toward US 49 North: Hattiesburg, Jackson

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward US 49 North: Hattiesburg, Jackson
5
25.3 mi into trip | ~33m in | US 49

Merge onto US 49

Merge point - match speed before joining. Lane positioning matters here

Use the straight lane.
5
158.7 mi into trip | ~3h 17m in | US 49

Keep slight left at fork onto US 49 toward Jackson

Highway fork - watch signs carefully

Toward Jackson
6
162 mi into trip | ~3h 22m in | I 20; US 49

Keep slight right at fork onto I 20; US 49 toward I 20 West, US 49 North: Vicksburg, Yazoo City

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 20 West, US 49 North: Vicksburg, Yazoo...

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Saint Martin, MS and Greenville, MS, road signs point toward Jackson, Yazoo City and Vicksburg.

Jackson

24.9 mi in | ~32m

Yazoo City

162 mi in | ~3h 22m | via I 20; US 49

Vicksburg

209.7 mi in | ~4h 21m | via US 49W

Main Roads

Road Distance Duration
US 49 140.6 mi 2h 53m
US 49W 46.7 mi 56m
Medgar Evers Boulevard 39.5 mi 48m
MS 15 20.7 mi 24m
US 82 15.8 mi 19m
MS 182 9.2 mi 13m
I 20 4.3 mi 5m
Lemoyne Boulevard 1.4 mi 2m
Longest stretch: US 49 — 140.6 mi, about 2h 53m

Turn-by-Turn Driving Directions

Step-by-step road directions between Saint Martin, MS and Greenville, MS.

1

Start on Needle Street

505 ft · 27 sec · Needle Street
2

Turn left onto Sundown Avenue

0.3 mi · 1 min · Sundown Avenue
3

At end of road, turn left onto Lemoyne Boulevard

1.4 mi · 2 min · Lemoyne Boulevard
4

Turn left onto Gorenflo Road

0.5 mi · 57 sec · Gorenflo Road
5

Turn right onto Rodriguez Street

0.2 mi · 35 sec · Rodriguez Street
6

Take the ramp

0.3 mi · 37 sec
7

Merge onto I 110

1.3 mi · 1 min · I 110
8

Continue on MS 15; MS 67

21 mi · 24 min · MS 15; MS 67
Use the straight lane.
9

Keep slight right at fork

0.4 mi · 47 sec
Toward US 49 North: Hattiesburg, Jackson
10

Merge onto US 49

40 mi · 46 min · US 49
Use the straight lane.
11

Continue on US 49

2.4 mi · 2 min · US 49
Use the straight / slight right lanes.
12

Turn straight onto US 49

10 mi · 16 min · US 49
Use the straight lane.
13

Continue on US 49; MS 42

5.4 mi · 6 min · US 49; MS 42
Use the straight lane.
14

Continue on US 49

5.3 mi · 6 min · US 49
Use the straight lane.
15

Continue on US 49

0.2 mi · 14 sec · US 49
Use the straight lane.
16

Continue on US 49

4.2 mi · 4 min · US 49
Use the straight lane.
17

Continue on US 49

66 mi · 1 hr 20 min · US 49
Use the straight lane.
18

Take the exit onto US 49

0.2 mi · 21 sec · US 49
19

Keep slight left at fork onto US 49

0.7 mi · 1 min · US 49
Toward Jackson
20

Keep slight left at fork onto US 49

1.0 mi · 1 min · US 49
21

Merge onto I 20; I 55; US 49

1.6 mi · 2 min · I 20; I 55; US 49
22

Keep slight right at fork onto I 20; US 49

2.7 mi · 3 min · I 20; US 49
Toward I 20 West, US 49 North: Vicksburg, Yazoo City
23

Take the exit onto US 49

5.2 mi · 6 min · US 49
Toward I 220 North, I 49 North: North Jackson, Yazoo City
24

Take the exit onto US 49

0.3 mi · 33 sec · US 49
Toward US 49 North: Yazoo City
25

Merge onto US 49

39 mi · 48 min · Medgar Evers Boulevard
26

Take the exit onto US 49W

47 mi · 56 min · US 49W
Toward US 49W North, MS 3 South: Indianola, Vicksburg
27

Turn left onto US 82

2.4 mi · 3 min · US 82
28

Keep slight left at fork onto US 82

0.4 mi · 29 sec · US 82
29

Keep slight left at fork onto US 82

13 mi · 15 min · US 82
30

Turn right onto MS 182

9.2 mi · 13 min · MS 182
31

Turn right onto South Main Street

0.9 mi · 2 min · South Main Street
32

Turn right onto MS 814

10 ft · 0 sec · South Broadway Street
33

Arrive at destination

MS 814

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 141.2 miles from Saint Martin, MS, or about 2h 56m into the drive.
The longest continuous stretch on this route runs about 140.6 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 62 miles or 1h 16m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 141.2 miles or 2h 56m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 47m

Traffic, exits, and arrival timing usually matter more near Greenville, MS than in the middle of the route.

Before You Leave

+

Open the route before leaving Saint Martin, MS so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Saint Martin, MS

This is one driving day of about 282.3 miles and 5h 53m.

Your first comfortable stop window is around 62 miles from Saint Martin, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 49 for about 140.6 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 141.2 mi from Saint Martin, MS · 2h 56m into the drive

Italian city and commune, located in Tuscany

Mid-route town

Meal stop

Florence, MS

141 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Wiggins, MS

Fuel and coffee

A short stop after about 62 miles helps settle the day before fatigue starts building.

Florence, MS

Meal break

The midpoint is around 141.2 miles from Saint Martin, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before US 49 if your tank is already low. That segment runs about 140.6 miles.

Arriving in Greenville, MS

The final approach into Greenville, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Greenville, MS.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$42.63 one way

$85.27 round trip

$3.84/gal 25.4 MPG avg 99 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.21 $46.80 $93.60
premium $4.56 $50.67 $101.34
diesel $5.61 $62.33 $124.66

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$43

Meals

$25–$50

Total

$68–$93

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 98.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $30 in charging · 1 stop · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 84.7 1 $29.64 $13.55
Efficient EV 70.6 0 $24.70 $11.29
EV Truck/SUV 112.9 1 $39.52 $18.07

Gas CO2

99 kg

EV CO2

33 kg (67% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Saint Martin, MS

Night in Saint Martin on Wednesday

Local time

11:42 PM

CDT

Current temp

58°F

Unavailable

Live forecast

Destination

Greenville, MS

Night in Greenville on Wednesday

Local time

11:42 PM

CDT

Current temp

77°F

Unavailable

Live forecast

55°F

Florence, MS

141 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

19 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 53m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Saint Martin, MS to Greenville, MS covers 282.3 miles and takes about 5h 53m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 49, US 49W, Medgar Evers Boulevard. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 141.2 miles from Saint Martin, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $42.63 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 23 significant decision points across 282.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.4 miles (Lemoyne Boulevard): Navigation decision point; at 24.9 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.3 miles (US 49): Merge point - match speed before joining. Lane positioning matters here.
Between Saint Martin, MS and Greenville, MS, road signs point toward Jackson, Yazoo City and Vicksburg.

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