Trip from San Antonio, TX to Amarillo, TX

Drive Time

7h 37m

Distance

511.2 mi

Route Type

Long-distance drive

Long day trip

Trip Overview

The drive from San Antonio, TX to Amarillo, TX covers 511.2 miles and takes about 7h 37m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on West Market Street, Navarro Street, San Pedro Avenue for much of the mileage, and the overall profile is long-distance drive. At current regular gas prices, budget about $76.06 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

2 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

255.6 miles from San Antonio, TX

A natural place for your longest stop of the day.

Drive Character

At 511.2 miles and 7h 37m of driving, this is a route where fuel stops, weather, and timing matter more than any single turn. The main roads are West Market Street and Navarro Street.

Expect a mix of faster highway mileage and slower local approaches near the beginning or end.

There are about 45 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

West Market Street is one of the defining roads on this drive.

Main Roads

Road	Distance	Duration
West Market Street	0 mi	0m
Navarro Street	0 mi	0m
San Pedro Avenue	0 mi	0m
West Cypress Street	0 mi	0m
East Fredericksburg Road	0 mi	0m
Interstate 10 West	0 mi	0m
I 10 West	0 mi	0m
McDermott Freeway	0 mi	0m

Longest stretch: West Market Street — 0 mi, about 0m

Step-by-Step Directions

1

Start on Dolorosa Street

2

Continue on West Market Street

3

Turn left onto Navarro Street

4

Enter the roundabout and take exit 2 toward San Pedro Avenue

5

Exit the roundabout onto San Pedro Avenue

6

Turn left onto West Cypress Street

7

Turn straight onto East Fredericksburg Road

8

Turn right onto Interstate 10 West

9

Take the ramp slight left toward I 10 West, US 87 North

10

Merge slight left onto McDermott Freeway

11

Keep slight right

12

Take the exit slight right toward US 83 North, US 377: Junction, Menard

13

Turn right onto North Main Street

14

Continue on Frisco Avenue

15

Continue on Roberts Avenue

16

Turn right onto Hutchings Avenue

17

Turn left onto North Broadway Street

18

Turn right

19

Turn left onto State Highway 153

20

Keep slight right to continue on State Highway 153

21

Turn right onto State Highway 70

22

Continue on Lamar Street

23

Turn left onto Northwest Georgia Avenue

24

Take the ramp slight left toward I 20 West: Midland

25

Merge slight left

26

Take the exit slight right toward US 84 West: Snyder, Lubbock

27

Keep slight left

28

Turn right onto South Avenue F

29

Keep slight left to continue on North Avenue F

30

Turn straight onto Ralls Road

31

Turn left onto East 15th Street

32

Turn right onto North US Highway 84

33

Continue on Highway 84

34

Continue on Trooper Jerry Don Davis Memorial Highway

35

Continue on East Highway 84

36

Continue on Slaton Road

37

Take the exit slight right

38

Turn slight right onto Interstate 27

39

Take the ramp straight

40

Merge slight left onto Marshall Formby Memorial Highway

41

Continue on Canyon Expressway

42

Keep slight left to continue on US 87 North

43

Keep slight right to continue on South Fillmore Street

44

Turn right onto East Amarillo Boulevard

45

Arrive at your destination

When to Leave

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.

Plan roughly 2 meaningful breaks for fuel, food, and rest.

The halfway point lands around 255.6 miles from San Antonio, TX.

This is a comfortable same-day trip.

Drive Plan

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 112 miles

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 255.6 miles

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Last hour of driving

Traffic, exits, and arrival timing usually matter more near Amarillo, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving San Antonio, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

Trip Strategy

Day 1

Settle into the route from San Antonio, TX

This is one driving day of about 511.2 miles and 7h 37m.

Your first comfortable stop window is around 112 miles from San Antonio, TX.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 2 real breaks rather than only quick fuel stops.

Best Stop Towns on This Route

These towns line up with the pace of this drive and give you clearer places to stop with a purpose.

Late stop town

Coffee and fuel

Abilene, TX

169 mi into the route

Best for: Coffee, fuel, and an easy first stretch

This is a natural early stop once the first hours of the drive are behind you.

Late stop town

Meal stop

Lubbock, TX

337 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Travel Advice

Arrival Notes

The final approach into Amarillo, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Amarillo, TX.

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Stops Along the Way

Halfway Point

Midpoint

About 255.6 mi from San Antonio, TX

Alamo Heights, TX

Fuel and coffee

A short stop after about 112 miles helps settle the day before fatigue starts building.

Anson, TX

Meal break

The midpoint is around 255.6 miles from San Antonio, TX, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Fuel Type	$/gal	One Way	Round Trip
regular	$3.78	$76.06	$152.11
midgrade	$4.25	$85.58	$171.15
premium	$4.59	$92.40	$184.80
diesel	$3.99	$80.36	$160.73

Based on 25.4 MPG average. Estimated CO2 emission: 178.9 kg one way.

Frequently Asked Questions

The drive from San Antonio, TX to Amarillo, TX covers 511.2 miles and takes about 7h 37m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are West Market Street, Navarro Street, San Pedro Avenue. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 255.6 miles from San Antonio, TX. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $76.06 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.

Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.