Origin
San Antonio, TX
Afternoon in San Antonio on Sunday
Local time
2:16 PM
CDT
Current temp
81°F
Unavailable
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Create accountDrive Time
8h 52m
Distance
506.9 mi
816 km
Drive Score
9/10
Great drive
Same Day?
2-day trip
Fuel Cost
$77
one way
San Antonio, TX
Wikimedia Commons
Amarillo, TX
Wikimedia Commons
Traveling from San Antonio to Amarillo is a significant journey across Texas, covering 511.2 miles of the Great Plains. You should budget approximately 7 hours and 37 minutes of total drive time, making this a long-distance haul that is best tackled in a single, focused day. With an estimated fuel cost of $76, you will want to account for your vehicle's specific efficiency before heading out. While the trip remains within the same state and region, the scale of the drive demands careful planning. Expect to make at least two stops to keep yourself alert and comfortable throughout the trek. It is a straightforward route, but the sheer length means you should be prepared for a full day of travel.
Trip Pace
Best split across 2 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
253.4 miles from San Antonio, TX
A natural place for your longest stop of the day , about 4h 29m into the drive .
Expect a unique experience as you depart San Antonio via city streets like West Market, Navarro, and San Pedro Avenue before transitioning to the open road. Because the route features 0% highway share according to the data, your drive will rely on a network of surface roads rather than the high-speed monotony of a major interstate. This structure changes the feel of the trip, requiring you to remain more engaged with navigation and road conditions. You will find that the journey lacks the typical long, uninterrupted interstate stretches, favoring a more localized driving experience. Prepare for a steady pace that keeps you focused on the road ahead as you traverse the expansive Texas landscape.
At 8h 52m, this is a long-haul route where pacing matters more than any single turn. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.2 miles in near Navarro Street.
High effort - long or complex enough to need steady focus all day
This is a demanding drive. With 32 significant decision points across 506.9 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.2 miles (Navarro Street): Lane positioning matters here; at 16.1 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here; at 114.7 miles (US 83): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn left onto Navarro Street
Lane positioning matters here
Keep slight right at fork onto I 10; US 87
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit onto US 83 toward US 83 North, US 377: Junction, Menard
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Turn right onto US 67; US 83 / Hutchings Avenue
Lane positioning matters here
Keep slight left at fork onto US 87 toward US 87 North
Highway fork - watch signs carefully. Lane positioning matters here
Between San Antonio, TX and Amarillo, TX, road signs point toward Menard and Lubbock.
Menard
Lubbock
| Road | Distance | Duration |
|---|---|---|
| Marshall Formby Memorial Highway | 109.9 mi | 1h 51m |
| I 10 | 98.7 mi | 1h 37m |
| US 84 | 74.5 mi | 1h 14m |
| Frisco Avenue | 41.9 mi | 44m |
| State Highway 153 | 29.5 mi | 33m |
| North Main Street | 29.3 mi | 30m |
| Highway 84 | 20 mi | 19m |
| Roberts Avenue | 16.5 mi | 18m |
Step-by-step road directions between San Antonio, TX and Amarillo, TX.
Start on Dolorosa Street
Continue on West Market Street
Turn left onto Navarro Street
Enter roundabout onto San Pedro Avenue
Continue on San Pedro Avenue
Turn left onto West Cypress Street
Turn straight onto East Fredericksburg Road
Turn right onto Interstate 10 West
Take the ramp
Merge onto I 10; US 87
Keep slight right at fork onto I 10; US 87
Take the exit onto US 83
Turn right onto US 83; US 377
Continue on US 83
Continue on US 83
Turn right onto US 67; US 83
Turn left onto TX 158
Turn right onto FM 2111
Turn left onto TX 153
Keep slight right at fork onto TX 153
Turn right onto TX 70
Continue on TX 70
Turn left onto Northwest Georgia Avenue
Take the ramp
Merge onto I 20; US 84
Take the exit onto US 84
Keep slight left at fork onto US 84
Turn right onto Loop 46
Keep slight left at fork onto TX 207
Turn straight onto TX 207
Turn left onto Spur 575
Turn right onto US 84
Continue on US 84
Continue on US 84
Continue on US 84
Continue on US 84
Take the exit
Turn slight right onto Interstate 27
Take the ramp
Merge onto I 27; US 87
Continue on I 27; US 60; US 87
Keep slight left at fork onto US 87
Keep slight right at fork onto US 87; Original US Route 66
Turn right onto I 40 Business; Original US Route 66; US 60
Arrive at destination
To manage this 511.2-mile trek effectively, aim for an early morning departure to ensure you reach Amarillo before nightfall. Since the route requires a significant time commitment, plan your two scheduled stops strategically to break up the monotony of the surface roads. Keep a close eye on your fuel gauge, as the $76 estimate may fluctuate depending on your vehicle's performance and local pump prices. Given the nature of these local roads, staying alert at intersections and changing speed limits is essential. A great tip for this specific route is to double-check your navigation settings before leaving San Antonio, as the reliance on surface streets rather than highways means you will encounter more turns and road transitions than a standard interstate drive.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
Consider an overnight stop or starting very early.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 112 miles or 1h 55m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 253.4 miles or 4h 29m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 253.4 miles or 4h 29m
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Final hour starts around 7h 47m
Traffic, exits, and arrival timing usually matter more near Amarillo, TX than in the middle of the route.
Open the route before leaving San Antonio, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.
Day 1
Settle into the route from San Antonio, TX
Aim for roughly 253 miles and 4.4 hours of wheel time on this day.
Day 2
Finish the approach into Amarillo, TX
Aim for roughly 253 miles and 4.4 hours of wheel time on this day.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 253.4 mi from San Antonio, TX · 4h 29m into the drive
First major stop
Coffee and fuel
167 mi into the route
Best for: Coffee, fuel, and an easy first stretch
This is a natural early stop once the first hours of the drive are behind you.
Second major stop
Overnight candidate
335 mi into the route
Best for: Hotel check-in, dinner, and a fresh start
This lines up well with a realistic day-end stop if you are breaking the drive into stages.
Find hotels in Post, TXNight 1
253 mi · about 4.4h in
A practical overnight split lands near Sweetwater, TX after about 253 miles or 4.4 hours of driving.
Find hotelsA short stop after about 112 miles helps settle the day before fatigue starts building.
The midpoint is around 253.4 miles from San Antonio, TX, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Marshall Formby Memorial Highway if your tank is already low. That segment runs about 109.9 miles.
Overnight split
Hotel stopFor a steadier pace, wrap day one after about 253 miles or 4.4 hours on the road.
The final approach into Amarillo, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Amarillo, TX.
On a multi-day trip, keep the last day a little lighter so you reach Amarillo, TX with some flexibility left in the schedule.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$77.43 one way
$154.86 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $84.86 | $169.71 |
| premium | $4.59 | $91.62 | $183.24 |
| diesel | $5.64 | $112.62 | $225.23 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$77
Hotel (1n)
$80–$140
Meals
$50–$100
Total
$207–$317
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 177.4 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $53 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 152.1 | 1 | $53.22 | $24.33 |
| Efficient EV | 126.7 | 1 | $44.35 | $20.28 |
| EV Truck/SUV | 202.8 | 2 | $70.97 | $32.44 |
Gas CO2
177 kg
EV CO2
59 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in San Antonio on Sunday
Local time
2:16 PM
CDT
Current temp
81°F
Unavailable
Destination
Afternoon in Amarillo on Sunday
Local time
2:16 PM
CDT
Current temp
46°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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