The drive from Scranton, PA to Saint Clair, PA covers 281.9 miles and takes about 5h 48m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Keystone Shortway, William Penn Highway, I 99 for much of the mileage,
and the overall profile is turn-heavy local drive.
The longest uninterrupted segment is about 98.5 miles on Keystone Shortway.
At current regular gas prices, budget about $46.74 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
141 miles from Scranton, PA
A natural place for your longest stop of the day
, about 2h 40m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 48m. Total distance: 281.9 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 48m drive, comfortable solo distance.
Scenic Drive
Turn-heavy local drive route profile with national parks nearby.
Drive Character
Expect a 5h 48m drive with frequent turns across 281.9 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 33 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Keystone Shortway is the longest continuous segment at about 98.5 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near Lackawanna Avenue.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 25 significant decision points across 281.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (Lackawanna Avenue): Complex interchange - multiple decisions in a short stretch; at 133.6 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 158.1 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 25 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
0.1 mi into trip|~0m in|Lackawanna Avenue
At end of road, turn left onto Lackawanna Avenue
Complex interchange - multiple decisions in a short stretch
6
133.6 mi into trip|~2h 31m in
Take the exit toward I 99 South, US 220 South, PA 26: Bellefonte
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 161
Toward I 99 South, US 220 South, PA 26: Bellefo...
6
158.1 mi into trip|~3h in|I 99; US 220
Keep slight left at fork onto I 99; US 220 toward I 99 South, US 220 South: Port Matilda, Altoona
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 99 South, US 220 South: Port Matilda,...
8
267.9 mi into trip|~5h 24m in|I 376; US 22 / Penn-Lincoln Parkway East
Keep slight right at fork onto I 376; US 22 / Penn-Lincoln Parkway East toward I 376 West, US 22 West: Pittsburgh
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left lane.
Toward I 376 West, US 22 West: Pittsburgh
7
279.8 mi into trip|~5h 41m in
Take the exit toward PA 885 South: Glenwood
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 73A
Toward PA 885 South: Glenwood
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Scranton, PA and Saint Clair, PA, road signs point toward Altoona and Hollidaysburg.
Altoona
158.1 mi in|~3h|via I 99; US 220
Hollidaysburg
191.9 mi in|~3h 37m
Main Roads
Road
Distance
Duration
Keystone Shortway
98.5 mi
1h 47m
William Penn Highway
61.2 mi
1h 25m
I 99
33.8 mi
36m
American Legion Memorial Highway
32.7 mi
39m
Jacksonville Road
24.2 mi
28m
Admiral Peary Highway
13.4 mi
19m
Penn-Lincoln Parkway East
11.8 mi
16m
River Street
0.9 mi
1m
Longest stretch:
Keystone Shortway
— 98.5 mi, about 1h 47m
Turn-by-Turn Driving Directions
Step-by-step road directions between Scranton, PA and Saint Clair, PA.
1
Start on Wyoming Avenue
0.1 mi·38 sec·Wyoming Avenue
2
At end of road, turn left onto Lackawanna Avenue
0.2 mi·24 sec·Lackawanna Avenue
3
Turn right onto CR 3023
0.2 mi·22 sec·Cedar Avenue
4
Continue on Cedar Avenue
400 ft·12 sec·Cedar Avenue
5
Turn left onto River Street
0.9 mi·1 min·River Street
6
Take the ramp
0.2 mi·28 sec
7
Merge onto I 81
33 mi·39 min·American Legion Memorial Highway
8
Take the exit
0.7 mi·1 min
Exit 151BToward I-80 West: Bloomsburg
9
Merge onto I 80
99 mi·1 hr 47 min·Keystone Shortway
10
Take the exit
0.3 mi·53 sec
Exit 161Toward I 99 South, US 220 South, PA 26: Bellefonte
11
Turn left onto US 220; PA 26
24 mi·28 min·Jacksonville Road
Use the straight lane.
12
Keep slight left at fork onto I 99; US 220
34 mi·36 min·I 99; US 220
Toward I 99 South, US 220 South: Port Matilda, Altoona
13
Take the exit
0.8 mi·1 min
Toward US 22: Ebensburg, Hollidaysburg
14
Continue on this road
0.5 mi·43 sec·this road
15
Continue on US 22
16 mi·19 min·William Penn Highway
16
Continue on US 22
13 mi·19 min·Admiral Peary Highway
Use the straight lane.
17
Continue on US 22
45 mi·1 hr 6 min·William Penn Highway
Use the straight / right lanes.
18
Keep slight right at fork onto I 376; US 22
12 mi·16 min·Penn-Lincoln Parkway East
Toward I 376 West, US 22 West: PittsburghUse the slight left lane.
19
Take the exit
478 ft·24 sec
Exit 73AToward PA 885 South: GlenwoodUse the slight right lane.
20
Turn right onto PA 885
0.1 mi·13 sec·Bates Street
Use the straight / right lanes.
21
Turn left onto PA 885
0.1 mi·19 sec·Second Avenue
Use the left / straight lanes.
22
Turn right onto Hot Metal Street
0.4 mi·1 min·Hot Metal Street
23
Turn right onto Sidney Street
0.2 mi·38 sec·Sidney Street
24
Turn left onto South 27th Street
0.3 mi·1 min·South 27th Street
25
At end of road, turn right onto Josephine Street
77 ft·4 sec·Josephine Street
26
Turn left onto Barry Street
0.1 mi·21 sec·Barry Street
27
Turn right onto Mission Street
0.2 mi·32 sec·Mission Street
28
Turn left onto Sterling Street
0.2 mi·37 sec·Sterling Street
29
Continue on Wellington Street
443 ft·20 sec·Wellington Street
30
Turn right onto Eleanor Street
0.3 mi·1 min·Eleanor Street
31
Turn left onto Charcot Street
435 ft·21 sec·Charcot Street
32
Turn right onto Clover Street
136 ft·6 sec·Clover Street
33
Arrive at destination
Clover Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 141 miles from Scranton, PA, or about 2h 40m into the drive.
The longest continuous stretch on this route runs about 98.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 62 miles or 1h 13m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 141 miles or 2h 40m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 30m
Traffic, exits, and arrival timing usually matter more near Saint Clair, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Scranton, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Scranton, PA
This is one driving day of about 281.9 miles and 5h 48m.
Your first comfortable stop window is around 62 miles from Scranton, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Keystone Shortway for about 98.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 141 mi from Scranton, PA
· 2h 40m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Johnstown Flood National Memorial
National Memorial
The South Fork Dam failed on Friday, May 31, 1889, and unleashed 20,000,000 tons of water that devastated Johnstown, PA. The flood killed 2,209 people but it brought the nation and the world together...
8 mi from route
~19 min detour
Free
near mile 213.9
On Tuesday morning, September 11, 2001, the U.S. came under attack when four commercial airliners were hijacked and used to strike targets on the ground. Nearly 3,000 people tragically lost their live...
27 mi from route
~66 min detour
Free
near mile 223.6
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$46.74 one way
$93.47 round trip
$4.21/gal25.4 MPG avg99 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.61
$51.19
$102.37
premium
$4.93
$54.67
$109.34
diesel
$5.61
$62.24
$124.48
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$47
Meals
$25–$50
Total
$72–$97
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 98.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $30 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
84.6
1
$29.60
$13.53
Efficient EV
70.5
0
$24.67
$11.28
EV Truck/SUV
112.8
1
$39.47
$18.04
Gas CO2
99 kg
EV CO2
33 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
Scranton, PA
Morning
in Scranton on Friday
Local time
8:29 AM
EDT
Current temp
43°F
Unavailable
Live forecast
Destination
Saint Clair, PA
Morning
in Saint Clair on Friday
Local time
8:29 AM
EDT
Current temp
84°F
Chance Showers And Thunderstorms
SW 14 mph45% chanceLive forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
41 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 48m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Scranton, PA to Saint Clair, PA covers 281.9 miles and takes about 5h 48m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Keystone Shortway, William Penn Highway, I 99. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 141 miles from Scranton, PA. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $46.74 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 25 significant decision points across 281.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.1 miles (Lackawanna Avenue): Complex interchange - multiple decisions in a short stretch; at 133.6 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 158.1 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Scranton, PA and Saint Clair, PA, road signs point toward Altoona and Hollidaysburg.
Yes. Nearby national parks include Johnstown Flood National Memorial and Flight 93 National Memorial.
How this page is built
Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from
OSRM
over
OpenStreetMap.
Fuel cost uses
EIA
weekly regional averages.
National park proximity is from the
NPS API.
Pages are published only after passing our data-quality checks; our
methodology page
documents refresh cadence, editorial standards, and known limitations.
