The drive from South Tucson, AZ to Glendale, AZ covers 124.5 miles and takes about 2h 16m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Casa Grande-Tucson Highway, Phoenix-Casa Grande Highway, Maricopa Freeway for much of the mileage,
and the overall profile is turn-heavy local drive.
The longest uninterrupted segment is about 54.5 miles on Casa Grande-Tucson Highway.
At current regular gas prices, budget about $24.80 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
62.2 miles from South Tucson, AZ
A natural place for your longest stop of the day
, about 1h 5m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 16m. Total distance: 124.5 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 16m drive, comfortable solo distance.
Scenic Drive
Turn-heavy local drive route profile with national parks nearby.
Drive Character
Expect a 2h 16m drive with frequent turns across 124.5 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 17 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Casa Grande-Tucson Highway is the longest continuous segment at about 54.5 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 9.9 miles in near I 10 / Casa Grande-Tucson Highway.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 9 significant decision points across 124.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 9.9 miles (I 10 / Casa Grande-Tucson Highway): Highway fork - watch signs carefully. Lane positioning matters here; at 110.7 miles (I 10 / Papago Freeway): Highway fork - watch signs carefully. Lane positioning matters here; at 112.7 miles (I 10 / Papago Freeway): Highway fork - watch signs carefully. Lane positioning matters here.
Critical Maneuvers
5 of 9 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
9.9 mi into trip|~12m in|I 10 / Casa Grande-Tucson Highway
Keep slight left at fork onto I 10 / Casa Grande-Tucson Highway
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
6
110.7 mi into trip|~1h 56m in|I 10 / Papago Freeway
Keep slight left at fork onto I 10 / Papago Freeway
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left lane.
6
112.7 mi into trip|~1h 58m in|I 10 / Papago Freeway
Keep slight left at fork onto I 10 / Papago Freeway
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
8
116.8 mi into trip|~2h 3m in
Take the exit toward 19th Avenue, Grand Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 143C
Toward 19th Avenue, Grand Avenue
6
117.1 mi into trip|~2h 4m in|North 19th Avenue
Turn right onto North 19th Avenue
Lane positioning matters here
Use the left / right lanes.
Main Roads
Road
Distance
Duration
Casa Grande-Tucson Highway
54.5 mi
55m
Phoenix-Casa Grande Highway
38.1 mi
38m
Maricopa Freeway
12 mi
13m
Grand Avenue
7.1 mi
12m
Papago Freeway
5.6 mi
6m
South Freeway
4.6 mi
5m
West 22nd Street
0.6 mi
<1m
Dean Lindsey Memorial Tunnel
0.5 mi
<1m
Longest stretch:
Casa Grande-Tucson Highway
— 54.5 mi, about 55m
Turn-by-Turn Driving Directions
Step-by-step road directions between South Tucson, AZ and Glendale, AZ.
1
Start on US 80 Hist
0.5 mi·1 min·South 6th Avenue
2
Turn left onto West 22nd Street
0.6 mi·54 sec·West 22nd Street
3
Turn right onto South Freeway Road
363 ft·11 sec·South Freeway Road
4
Take the ramp
0.3 mi·43 sec
Toward I 10 West
5
Merge onto I 10
4.6 mi·5 min·South Freeway
Use the straight / slight right lanes.
6
Continue on I 10
3.7 mi·4 min·Casa Grande-Tucson Highway
Use the straight / slight right lanes.
7
Keep slight left at fork onto I 10
51 mi·51 min·Casa Grande-Tucson Highway
Use the straight / slight right lanes.
8
Continue on I 10
38 mi·38 min·Phoenix-Casa Grande Highway
Use the straight / slight right lanes.
9
Continue on I 10
12 mi·13 min·Maricopa Freeway
Use the straight / slight right lanes.
10
Keep slight left at fork onto I 10
2.0 mi·2 min·Papago Freeway
Use the slight left lane.
11
Keep slight left at fork onto I 10
2.7 mi·3 min·Papago Freeway
Use the straight / slight right lanes.
12
Continue on I 10
0.5 mi·36 sec·Dean Lindsey Memorial Tunnel
13
Continue on I 10
0.9 mi·1 min·Papago Freeway
Use the straight / slight right lanes.
14
Take the exit
0.3 mi·46 sec
Exit 143CToward 19th Avenue, Grand AvenueUse the straight / slight right lanes.
15
Turn right onto North 19th Avenue
0.3 mi·35 sec·North 19th Avenue
Use the left / right lanes.
16
Turn slight left onto Grand Avenue
7.1 mi·12 min·Grand Avenue
Use the left / slight left lanes.
17
Arrive at destination
US 60
Trip Plan
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 62.2 miles from South Tucson, AZ, or about 1h 5m into the drive.
The longest continuous stretch on this route runs about 54.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 27 miles or 29m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 62.2 miles or 1h 5m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 46m
Traffic, exits, and arrival timing usually matter more near Glendale, AZ than in the middle of the route.
Before You Leave
+
Open the route before leaving South Tucson, AZ so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from South Tucson, AZ
This is one driving day of about 124.5 miles and 2h 16m.
Your first comfortable stop window is around 27 miles from South Tucson, AZ.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Casa Grande-Tucson Highway for about 54.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 62.2 mi from South Tucson, AZ
· 1h 5m into the drive
The midpoint is around 62.2 miles from South Tucson, AZ, which is a good place for a longer meal and fuel stop.
Arriving in Glendale, AZ
The final approach into Glendale, AZ usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Glendale, AZ.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Casa Grande Ruins National Monument
National Monument
An Ancestral Sonoran Desert People's farming community and "Great House" are preserved at Casa Grande Ruins. Whether a gathering place for people or simply a waypoint marker in an extensive system of...
10 mi from route
~26 min detour
Free
near mile 68.7
Tucson, Arizona is home to the nation's largest cacti. The giant saguaro is the universal symbol of the American west. These majestic plants, found only in a small portion of the United States, are pr...
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$24.80 one way
$49.60 round trip
$5.06/gal25.4 MPG avg44 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$5.36
$26.25
$52.50
premium
$5.59
$27.40
$54.81
diesel
$5.61
$27.49
$54.98
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$25
Meals
$25–$50
Total
$50–$75
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 43.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $13 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
37.4
0
$13.07
$5.98
Efficient EV
31.1
0
$10.89
$4.98
EV Truck/SUV
49.8
0
$17.43
$7.97
Gas CO2
44 kg
EV CO2
15 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
South Tucson, AZ
Afternoon
in South Tucson on Friday
Local time
12:21 PM
MST
Current temp
55°F
Unavailable
Live forecast
Destination
Glendale, AZ
Afternoon
in Glendale on Friday
Local time
12:21 PM
MST
Current temp
92°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
37 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 16m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from South Tucson, AZ to Glendale, AZ covers 124.5 miles and takes about 2h 16m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Casa Grande-Tucson Highway, Phoenix-Casa Grande Highway, Maricopa Freeway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 62.2 miles from South Tucson, AZ. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $24.80 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a demanding drive. With 9 significant decision points across 124.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 9.9 miles (I 10 / Casa Grande-Tucson Highway): Highway fork - watch signs carefully. Lane positioning matters here; at 110.7 miles (I 10 / Papago Freeway): Highway fork - watch signs carefully. Lane positioning matters here; at 112.7 miles (I 10 / Papago Freeway): Highway fork - watch signs carefully. Lane positioning matters here.
The route from South Tucson, AZ to Glendale, AZ does not surface many named destination signs beyond the main corridor.
Yes. Nearby national parks include Casa Grande Ruins National Monument and Saguaro National Park.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
