Roma Italian Restaurant
Around the midpoint, short detour
Clinton, Mississippi
Hours: 11 am–9 pm
+16014884850
Visit websiteCompiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
5h 53m
Distance
309.5 mi
498 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$47
one way
EV Charging
Good
8 stations
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Southaven, MS
大 董
Carthage, MS
Wikimedia Commons
The drive from Southaven, MS to Carthage, MS covers 309.5 miles and takes about 5h 53m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 55, US 61, I 20 for much of the mileage, and the overall profile is mostly highway. The longest uninterrupted segment is about 185.9 miles on I 55. At current regular gas prices, budget about $46.74 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
154.7 miles from Southaven, MS
A natural place for your longest stop of the day , about 2h 48m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 55 | 185.9 mi | 3h 19m |
| US 61 | 69.9 mi | 1h 19m |
| I 20 | 32.8 mi | 35m |
| Natchez Trace Parkway | 6.4 mi | 9m |
| I 220 | 5.9 mi | 6m |
| Carthage Point Road | 2.3 mi | 8m |
| Medgar Evers Boulevard | 2 mi | 2m |
| Highland Boulevard | 1 mi | 2m |
Step-by-step road directions between Southaven, MS and Carthage, MS.
Start on Five Oaks Drive West
Turn right onto Haleville Drive
At end of road, turn left onto Millbranch Road
Turn right onto Stateline Road West
Take the ramp
Merge onto I 55; I 69
Take the exit
Continue on I 220
Take the exit
Keep slight right at fork
Merge onto US 49
Take the exit
Turn right onto Natchez Trace Parkway
Take the ramp
Merge onto I 20; US 80
Merge onto I 20; US 61; US 80
Keep slight left at fork onto US 61
Turn right onto Highland Boulevard
Turn left onto Lower Woodville Road
Continue on Carthage Point Road
Turn slight right
Arrive at destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 68 miles or 1h 15m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 154.7 miles or 2h 48m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 41m
Traffic, exits, and arrival timing usually matter more near Carthage, MS than in the middle of the route.
Open the route before leaving Southaven, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Southaven, MS
This is one driving day of about 309.5 miles and 5h 53m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
155 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 68 miles helps settle the day before fatigue starts building.
The midpoint is around 154.7 miles from Southaven, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 55 if your tank is already low. That segment runs about 185.9 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
Clinton, Mississippi
Around the midpoint, short detour
Hours: 11 am–9 pm
+16014884850
The Delta Bean Coffee Shop
Grenada, Mississippi
Top Coffee Stop
Grenada, Mississippi
Early in the drive, short detour
Hours: 5 am–1 pm
+16018121486
Quarter Boyz mc clubhouse
Grenada, Mississippi
Around the midpoint, short detour
Clinton, Mississippi
Hours: 11 am–9 pm
+16014884850
Visit websiteAround the midpoint, short detour
Clinton, Mississippi
Hours: 11 am–10 pm
+16019240005
Visit websiteEarly in the drive, short detour
Grenada, Mississippi
Hours: 6 am–5 pm
+16623077323
Near the end, short detour
Natchez, Mississippi
Hours: 11 am–2:30 pm
+16013045802
Near the start, ~10 min detour
Senatobia, MS
Hours: 11 am–3 pm
+16623011478
Visit websiteNear the end, ~10 min detour
Port Gibson, Mississippi
Hours: 6:30 am–11 pm
+16014481360
Visit websiteNear the start, ~12 min detour
Senatobia, Mississippi
Hours: 10:30 am–9 pm
+16623018538
Visit websiteNear the start, ~12 min detour
Batesville, Mississippi
Hours: 9 am–2 pm
+16625638941
Visit websiteEarly in the drive, short detour
Grenada, Mississippi
Hours: 5 am–1 pm
+16018121486
Early in the drive, short detour
Grenada, Mississippi
Hours: 6:30 am–6:30 pm
Visit websiteEarly in the drive, short detour
Grenada, Mississippi
Early in the drive, short detour
Grenada, Mississippi
+16626883951
Around the midpoint, ~10 min detour
Winona, Mississippi
Hours: 6:30 am–4 pm
+16626336811
Early in the drive, short detour
Grenada, Mississippi
Hours: 6:30 am–5 pm
+16625616063
Around the midpoint, ~9 min detour
Winona, Mississippi
Hours: 5 am–1 pm
+16622296266
Around the midpoint, ~10 min detour
Winona, Mississippi
Hours: 6 am–5 pm
Near the start, short detour
Southaven, Mississippi
Hours: Open 24 hours
+18777983752
Visit websiteNear the start, short detour
Horn Lake, Mississippi
Hours: Open 24 hours
+18777983752
Visit websiteNear the end, ~9 min detour
Natchez, Mississippi
+18773862273
Visit websiteNear the start, short detour
Memphis, Tennessee
Hours: 7 am–5 pm
+19013102301
Visit websiteAround the midpoint, ~9 min detour
Winona, Mississippi
Hours: Open 24 hours
+18774943833
Visit websiteNear the end, ~10 min detour
Natchez, Mississippi
+16013045378
Visit websiteNear the start, short detour
Southaven, Mississippi
Hours: Open 24 hours
+18776642738
Visit websiteNear the end, short detour
Natchez, Mississippi
Hours: Open 24 hours
+16014424462
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 0.1 and 235.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn right onto Haleville Drive
Navigation decision point
At end of road, turn left onto Millbranch Road
Complex interchange - multiple decisions in a short stretch
Keep slight right at fork toward US 49 North: Yazoo City
Highway fork - watch signs carefully
Take the ramp toward 20
Navigation decision point
Keep slight left at fork onto US 61 toward US 61 South: Natchez
Highway fork - watch signs carefully. Lane positioning matters here
Regular Gas
$46.74 one way
$93.48 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.21 | $51.31 | $102.62 |
| premium | $4.56 | $55.55 | $111.10 |
| diesel | $5.61 | $68.33 | $136.67 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$47
Meals
$25–$50
Total
$72–$97
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 108.3 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $33 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 92.9 | 1 | $32.50 | $14.86 |
| Efficient EV | 77.4 | 0 | $27.08 | $12.38 |
| EV Truck/SUV | 123.8 | 1 | $43.33 | $19.81 |
Gas CO2
108 kg
EV CO2
36 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Southaven on Saturday
Local time
1:24 PM
CDT
Current temp
56°F
Unavailable
Destination
Afternoon in Carthage on Saturday
Local time
1:24 PM
CDT
Current temp
57°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
National Historical Park
Discover the history of all the peoples of Natchez, Mississippi, from European settlement, African enslavement, the American cotton economy, to the Civil Rights struggle on the lower Mississippi River...
National Monument
In 1955, 14-year-old Emmett Till traveled to Money, Mississippi, to visit relatives. He was kidnapped, tortured, and murdered after reportedly whistling at a white woman. His mother, Mamie Till-Mobley...
Park data from the National Park Service API. Alerts update every 2 hours.
309.5 mi in 5h 53m, mostly highway — 185.9 mi of that is on I 55.
This is a straightforward highway drive that stays mostly on I 55 and US 61. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near Haleville Drive.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 309.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (Haleville Drive): Navigation decision point; at 0.3 miles (Millbranch Road): Complex interchange - multiple decisions in a short stretch; at 193.7 miles: Highway fork - watch signs carefully.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Southaven, MS to Carthage, MS, road signs begin pointing toward Ntp along the way.
Ntp
Weekend Trip
Doable as a same-day drive at 5h 53m. Total distance: 309.5 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 53m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (97%). Some complex stretches to watch for.
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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