The drive from Southaven, MS to Quitman, MS covers 262.6 miles and takes about 5h 7m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 78, US Highway 45 Aiternate, US Highway 45 Alternate for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 83.4 miles on US 78.
At current regular gas prices, budget about $40.14 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
131.3 miles from Southaven, MS
A natural place for your longest stop of the day
, about 2h 33m into the drive
.