Trip from St. Louis, MO to Duquesne, MO

Data updated 1 hour ago

Drive Time

5h 14m

Distance

281.7 mi

453 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$44

one way

EV Charging

None

0 DC fast

Best Time to Leave

Save up to 41 min

4 AM

5h 1m ★

6 AM

5h 15m

8 AM

5h 42m

10 AM

5h 24m

12 PM

5h 21m

3 PM

5h 25m

5 PM

5h 40m

8 PM

5h 7m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly

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Trip Overview

The drive from St. Louis, MO to Duquesne, MO covers 281.7 miles and takes about 5h 14m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Henry Shaw Ozark Corridor, I 44 Business, Police Officer Ernest M. Brockman Sr. Memorial Highway for much of the mileage, and the overall profile is turn-heavy local drive. The longest uninterrupted segment is about 261.3 miles on Henry Shaw Ozark Corridor. At current regular gas prices, budget about $44.04 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

140.9 miles from St. Louis, MO

A natural place for your longest stop of the day , about 2h 37m into the drive .

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Drive Character

Expect a 5h 14m drive with frequent turns across 281.7 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.

There are about 11 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

Henry Shaw Ozark Corridor is the longest continuous segment at about 261.3 miles.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes around 1 miles in near South Jefferson Avenue.

Route Complexity 3/10

Easy - simple navigation with a manageable amount of wheel time

This is a straightforward 5h 14m drive. You will face about 5 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

The main spots that need attention: at 1 miles (South Jefferson Avenue): Navigation decision point; at 2.2 miles: Navigation decision point; at 2.4 miles (I 44 / Officer David Haynes Memorial Highway): Merge point - match speed before joining.

Critical Maneuvers

5 of 5 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

3

1 mi into trip | ~2m in | South Jefferson Avenue

Turn left onto South Jefferson Avenue

Navigation decision point

3

2.2 mi into trip | ~4m in

Take the ramp toward I 44 West

Navigation decision point

Toward I 44 West

3

2.4 mi into trip | ~4m in | I 44 / Officer David Haynes Memorial Highway

Merge onto I 44 / Officer David Haynes Memorial Highway

Merge point - match speed before joining

8

275.7 mi into trip | ~5h 4m in | I 44 Business; MO 66

Take the exit onto I 44 Business; MO 66 toward I 44 Business, MO 66: Duenweg, Joplin

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / right lanes. Exit 15 Toward I 44 Business, MO 66: Duenweg, Joplin

3

281.2 mi into trip | ~5h 13m in | Duquesne Road

Turn left onto Duquesne Road

Navigation decision point

Main Roads

Road	Distance	Duration
Henry Shaw Ozark Corridor	261.3 mi	4h 43m
I 44 Business	5.5 mi	9m
Police Officer Ernest M. Brockman Sr. Memorial Highway	3.5 mi	4m
Officer Michael Barwick Memorial Highway	3.5 mi	4m
Police Officer Robert Stanze Memorial Highway	2.7 mi	3m
Officer David Haynes Memorial Highway	2.3 mi	3m
South Jefferson Avenue	1.2 mi	2m
Market Street	1 mi	2m

Longest stretch: Henry Shaw Ozark Corridor — 261.3 mi, about 4h 43m

Turn-by-Turn Driving Directions

Step-by-step road directions between St. Louis, MO and Duquesne, MO.

1

Start on Market Street

1.0 mi · 2 min · Market Street

2

Turn left onto South Jefferson Avenue

1.2 mi · 2 min · South Jefferson Avenue

3

Take the ramp

0.2 mi · 17 sec

Toward I 44 West

4

Merge onto I 44

2.3 mi · 3 min · Officer David Haynes Memorial Highway

5

Continue on I 44

3.5 mi · 4 min · Officer Michael Barwick Memorial Highway

6

Continue on I 44

2.7 mi · 3 min · Police Officer Robert Stanze Memorial Highway

7

Continue on I 44

3.5 mi · 4 min · Police Officer Ernest M. Brockman Sr. Memorial Highway

8

Continue on I 44; US 50

261 mi · 4 hr 43 min · Henry Shaw Ozark Corridor

Use the straight / slight right lanes.

9

Take the exit onto I 44 Business; MO 66

5.5 mi · 9 min · I 44 Business; MO 66

Exit 15 Toward I 44 Business, MO 66: Duenweg, Joplin Use the straight / right lanes.

10

Turn left onto Duquesne Road

0.5 mi · 1 min · Duquesne Road

11

Arrive at destination

Duquesne Road

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 140.9 miles from St. Louis, MO, or about 2h 37m into the drive.

The longest continuous stretch on this route runs about 261.3 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 31m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 140.9 miles or 2h 37m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 15m

Traffic, exits, and arrival timing usually matter more near Duquesne, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving St. Louis, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from St. Louis, MO

This is one driving day of about 281.7 miles and 5h 14m.

Your first comfortable stop window is around 80 miles from St. Louis, MO.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

The longest stretch is on Henry Shaw Ozark Corridor for about 261.3 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 140.9 mi from St. Louis, MO · 2h 37m into the drive

archaeological site near East St. Louis, Illinois, USA

Mid-route town

Meal stop

Cahokia, IL

141 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Cahokia, IL

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Cahokia, IL

Meal break

The midpoint is around 140.9 miles from St. Louis, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Henry Shaw Ozark Corridor if your tank is already low. That segment runs about 261.3 miles.

Arriving in Duquesne, MO

The final approach into Duquesne, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Duquesne, MO.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

National Parks Near This Route

Worth a detour if your schedule allows.

Gateway Arch National Park

National Park

Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...

0 mi from route ~1 min detour $19

View on nps.gov

George Washington Carver National Monument

National Monument

The young child known as the "Plant Doctor" tended his secret garden while observing the day-to-day operations of a 19th century farm. Nature and nurture ultimately influenced George on his quest for...

7 mi from route ~19 min detour Free near mile 272

View on nps.gov

Wilson's Creek National Battlefield

National Battlefield

Wilson's Creek was the first major Civil War battle fought west of the Mississippi River, and where the first Union general was killed in action. The costly Southern victory on August 10, 1861, focuse...

7 mi from route ~17 min detour Free near mile 223.4

View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

Fuel & Cost

Regular Gas

$44.04 one way

$88.08 round trip

$3.97/gal 25.4 MPG avg 99 kg CO₂

Fuel Type	$/gal	One Way	Round Trip
midgrade	$4.36	$48.35	$96.71
premium	$4.89	$54.21	$108.42
diesel	$5.61	$62.20	$124.39

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$44

Meals

$25–$50

Total

$69–$94

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 98.6 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $30 in charging · 1 stop · 67% less CO₂

Vehicle Type	kWh	Stops	DC Fast	Home Charge
Average EV	84.5	1	$29.58	$13.52
Efficient EV	70.4	0	$24.65	$11.27
EV Truck/SUV	112.7	1	$39.44	$18.03

Gas CO2

99 kg

EV CO2

33 kg (67% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 5 days ago

Origin

St. Louis, MO

Afternoon in St. Louis on Tuesday

Local time

4:37 PM

CDT

Current temp

59°F

Unavailable

Live forecast

Destination

Duquesne, MO

Afternoon in Duquesne on Tuesday

Local time

4:37 PM

CDT

Current temp

57°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

2 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 14m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from St. Louis, MO to Duquesne, MO covers 281.7 miles and takes about 5h 14m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are Henry Shaw Ozark Corridor, I 44 Business, Police Officer Ernest M. Brockman Sr. Memorial Highway. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 140.9 miles from St. Louis, MO. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $44.04 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

This is a straightforward 5h 14m drive. You will face about 5 decision points, but nothing that requires special attention if you follow navigation.

The main spots that need attention: at 1 miles (South Jefferson Avenue): Navigation decision point; at 2.2 miles: Navigation decision point; at 2.4 miles (I 44 / Officer David Haynes Memorial Highway): Merge point - match speed before joining.

The route from St. Louis, MO to Duquesne, MO does not surface many named destination signs beyond the main corridor.

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