Origin
St. Louis, MO
Evening in St. Louis on Thursday
Local time
5:07 PM
CDT
Current temp
74°F
Unavailable
Live forecast
Trip from St. Louis, MO to Mound City, MO
Last recalculated Apr 16, 2026
Drive Time
6h 26m
Distance
340.3 mi
548 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$53
one way
EV Charging
Unknown
Best Time to Leave
4 AM
6h 14m
★
6 AM
6h 27m
8 AM
6h 51m
10 AM
6h 35m
12 PM
6h 33m
3 PM
6h 37m
5 PM
6h 50m
8 PM
6h 19m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Mound City, MO
Wikimedia Commons
Trip Overview
The drive from St. Louis, MO to Mound City, MO covers 340.3 miles and takes about 6h 26m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 64 West, Jack Buck Memorial Highway, Daniel Boone Expressway for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $53.20 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
170.1 miles from St. Louis, MO
A natural place for your longest stop of the day , about 3h 13m into the drive .
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 26m. Total distance: 340.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 26m drive, plan rest stops for pacing.
First-Time Driver
Mostly highway driving (0%). Straightforward navigation.
Scenic Drive
Turn-heavy local drive route profile.
Drive Character
Expect a 6h 26m drive with frequent turns across 340.3 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 27 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 64 West is one of the defining roads on this drive.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Driving Effort
3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
The route itself is not hard, but at 6h 26m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from St. Louis, MO to Mound City, MO is straightforward, with well-signed roads and simple exits.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 64 West | — | — |
| Jack Buck Memorial Highway | — | — |
| Daniel Boone Expressway | — | — |
| Avenue of the Saints | — | — |
| I 70 West | — | — |
| Dwight D Eisenhower Highway | — | — |
| Sheriff Roger I | — | — |
| Highway Patrol Sgt | — | — |
Some road-level metrics are being recalculated.
Longest stretch:
I 64 West
— detailed segment metrics are refreshing.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis, MO and Mound City, MO.
1
Start on Market Street
1.6 mi
·
3 min
·
Market Street
2
Take the ramp slight left toward I 64 West, US 40 West: Wentzville
0.3 mi
·
24 sec
·
I 64 West, US 40 West: Wentzville
3
Merge slight left onto Jack Buck Memorial Highway
4.3 mi
·
5 min
·
Jack Buck Memorial Highway
4
Continue on Daniel Boone Expressway
5.7 mi
·
7 min
·
Daniel Boone Expressway
5
Continue on Avenue of the Saints
28 mi
·
33 min
·
Avenue of the Saints
6
Take the exit slight left toward I 70 West, US 40 West: Kansas City
0.6 mi
·
1 min
·
I 70 West, US 40 West: Kansas City
7
Merge slight left onto Dwight D Eisenhower Highway
81 mi
·
1 hr 35 min
·
Dwight D Eisenhower Highway
8
Continue on Sheriff Roger I. Wilson Memorial Highway
2.0 mi
·
2 min
·
Sheriff Roger I. Wilson Memorial Highway
9
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi
·
1 min
·
Highway Patrol Sgt. Benjamin Booth Memorial Highway
10
Continue on Dwight D. Eisenhower Highway
1.8 mi
·
2 min
·
Dwight D. Eisenhower Highway
11
Continue on U.S. Submarine Veterans' Memorial Highway
54 mi
·
58 min
·
U.S. Submarine Veterans' Memorial Highway
12
Continue on Dwight D. Eisenhower Highway
52 mi
·
56 min
·
Dwight D. Eisenhower Highway
13
Continue on Truman/Eisenhower Presidential Highway
2.7 mi
·
3 min
·
Truman/Eisenhower Presidential Highway
14
Continue on Clifton J. Scott Memorial Highway
1.8 mi
·
2 min
·
Clifton J. Scott Memorial Highway
15
Continue on Truman/Eisenhower Presidential Highway
2.9 mi
·
3 min
·
Truman/Eisenhower Presidential Highway
16
Continue on George Brett Super Highway
0.8 mi
·
58 sec
·
George Brett Super Highway
17
Take the exit slight right toward I 435 North, US 24 East: Des Moines
1.1 mi
·
2 min
·
I 435 North, US 24 East: Des Moines
18
Merge slight left onto Lamar Hunt Memorial Highway
7.8 mi
·
9 min
·
Lamar Hunt Memorial Highway
19
Continue on I435 N
1.3 mi
·
1 min
·
I435 N
20
Continue straight
21 mi
·
22 min
21
Keep slight left to continue on I 29 North, US 71 North: Saint Joseph
37 mi
·
40 min
·
I 29 North, US 71 North: Saint Joseph
22
Continue straight
30 mi
·
32 min
23
Take the exit slight right toward MO 118: Mound City
0.2 mi
·
20 sec
·
MO 118: Mound City
24
Turn right
0.2 mi
·
21 sec
25
Turn right onto State Street
0.2 mi
·
49 sec
·
State Street
26
Turn left
98 ft
·
7 sec
27
Arrive at your destination
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 170.1 miles from St. Louis, MO, or about 3h 13m into the drive.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 75 miles or 1h 25m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 170.1 miles or 3h 13m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 18m
Traffic, exits, and arrival timing usually matter more near Mound City, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving St. Louis, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from St. Louis, MO
This is one driving day of about 340.3 miles and 6h 26m.
Your first comfortable stop window is around 75 miles from St. Louis, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 170.1 mi from St. Louis, MO · 3h 13m into the drive
Mid-route town
Meal stop
170 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 75 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 170.1 miles from St. Louis, MO, which is a good place for a longer meal and fuel stop.
Arriving in Mound City, MO
The final approach into Mound City, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Mound City, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$53.20 one way
$106.40 round trip
$3.97/gal
25.4 MPG avg
119 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $58.41 | $116.83 |
| premium | $4.89 | $65.49 | $130.98 |
| diesel | $5.61 | $75.13 | $150.27 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$53
Meals
$25–$50
Total
$78–$103
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 119.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $36 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 102.1 | 1 | $35.73 | $16.33 |
| Efficient EV | 85.1 | 0 | $29.78 | $13.61 |
| EV Truck/SUV | 136.1 | 1 | $47.64 | $21.78 |
Gas CO2
119 kg
EV CO2
40 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Mound City, MO
Evening in Mound City on Thursday
Local time
5:07 PM
CDT
Current temp
75°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 26m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from St. Louis, MO to Mound City, MO covers 340.3 miles and takes about 6h 26m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 64 West, Jack Buck Memorial Highway, Daniel Boone Expressway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 170.1 miles from St. Louis, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $53.20 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
The route itself is not hard, but at 6h 26m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
This route does not have any notably tricky sections. Most of the drive from St. Louis, MO to Mound City, MO is straightforward, with well-signed roads and simple exits.
The route from St. Louis, MO to Mound City, MO does not surface many named destination signs beyond the main corridor.
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