Origin
Tallahassee, FL
Afternoon in Tallahassee on Saturday
Local time
4:41 PM
EDT
Current temp
81°F
Unavailable
Live forecast
Trip from Tallahassee, FL to San Antonio, FL
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
4h 37m
Distance
245.7 mi
395 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$39
one way
EV Charging
Unknown
Best Time to Leave
4 AM
4h 24m
★
6 AM
4h 37m
8 AM
5h 4m
10 AM
4h 46m
12 PM
4h 44m
3 PM
4h 48m
5 PM
5h 3m
8 PM
4h 29m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Tallahassee, FL
Wikimedia Commons
San Antonio, FL
Anne
Trip Overview
The drive from Tallahassee, FL to San Antonio, FL covers 245.7 miles and takes about 4h 37m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on East Pensacola Street, South Franklin Boulevard, East Tennessee Street for much of the mileage, and the overall profile is mostly surface roads. At current regular gas prices, budget about $39.11 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
122.9 miles from Tallahassee, FL
A natural place for your longest stop of the day , about 2h 18m into the drive .
Main Roads
| Road | Distance | Duration |
|---|---|---|
| East Pensacola Street | — | — |
| South Franklin Boulevard | — | — |
| East Tennessee Street | — | — |
| Mahan Drive | — | — |
| I 10 East | — | — |
| I-75 South | — | — |
| CR 41 | — | — |
| Blanton Road | — | — |
Some road-level metrics are being recalculated.
Longest stretch:
East Pensacola Street
— detailed segment metrics are refreshing.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tallahassee, FL and San Antonio, FL.
1
Start on South Monroe Street
180 ft
·
8 sec
·
South Monroe Street
2
Turn right onto East Pensacola Street
0.3 mi
·
47 sec
·
East Pensacola Street
3
Turn left onto South Franklin Boulevard
0.5 mi
·
1 min
·
South Franklin Boulevard
4
Turn right onto East Tennessee Street
0.6 mi
·
1 min
·
East Tennessee Street
5
Continue on Mahan Drive
6.5 mi
·
11 min
·
Mahan Drive
6
Take the ramp slight right toward I 10 East: Lake City
0.7 mi
·
1 min
·
I 10 East: Lake City
7
Merge slight left
87 mi
·
1 hr 33 min
8
Take the exit slight right toward I-75 South: Tampa
0.4 mi
·
37 sec
·
I-75 South: Tampa
9
Merge slight left
142 mi
·
2 hr 32 min
10
Take the exit slight right toward CR 41: Dade City
0.1 mi
·
23 sec
·
CR 41: Dade City
11
Keep slight right
256 ft
·
6 sec
12
Turn straight onto Blanton Road
1.6 mi
·
2 min
·
Blanton Road
13
Turn right onto James Road
0.2 mi
·
43 sec
·
James Road
14
Turn left onto Jessamine Road
3.0 mi
·
5 min
·
Jessamine Road
15
Continue on Curley Road
2.2 mi
·
4 min
·
Curley Road
16
Continue on Curley Street
0.7 mi
·
1 min
·
Curley Street
17
Turn right onto Pennsylvania Avenue
62 ft
·
3 sec
·
Pennsylvania Avenue
18
Arrive at your destination
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 122.9 miles from Tallahassee, FL, or about 2h 18m into the drive.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 54 miles or 1h in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 122.9 miles or 2h 18m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 47m
Traffic, exits, and arrival timing usually matter more near San Antonio, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Tallahassee, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Tallahassee, FL
This is one driving day of about 245.7 miles and 4h 37m.
Your first comfortable stop window is around 54 miles from Tallahassee, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
123 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 54 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 122.9 miles from Tallahassee, FL, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$39.11 one way
$78.22 round trip
$4.04/gal
25.4 MPG avg
86 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.40 | $42.54 | $85.09 |
| premium | $4.72 | $45.69 | $91.37 |
| diesel | $5.61 | $54.25 | $108.49 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$39
Meals
$25–$50
Total
$64–$89
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 86 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $26 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 73.7 | 0 | $25.80 | $11.79 |
| Efficient EV | 61.4 | 0 | $21.50 | $9.83 |
| EV Truck/SUV | 98.3 | 1 | $34.40 | $15.72 |
Gas CO2
86 kg
EV CO2
29 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
San Antonio, FL
Afternoon in San Antonio on Saturday
Local time
4:41 PM
EDT
Current temp
60°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
21 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 37m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
What kind of drive is this?
245.7 mi in 4h 37m across surface roads — expect steady turns and local traffic rather than long highway runs.
Only 0% highway — the rest is turn-by-turn surface driving.
18 navigation steps total — most of the decisions cluster near the start and finish.
Main road: East Pensacola Street.
How Hard Is This Drive?
3/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Driving Effort
3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 4h 37m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Tallahassee, FL to San Antonio, FL is straightforward, with well-signed roads and simple exits.
About the Cities
Starting in Tallahassee, FL
Full guide →Tallahassee is the capital city of Florida, in the Florida Panhandle region of the state. In addition to housing the state government, it is a university town home to Florida State University, Florida A&M University, and Tallahassee Community College. Tallahassee has a good selection of restaurants for a city of its size. The universities' theater, art, and music programs, in addition to an active Council of Culture and Arts, also make for an unusually vibrant arts scene.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h 37m. Total distance: 245.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 37m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (0%). Straightforward navigation.
Scenic Drive
Mostly surface roads route profile.
Frequently Asked Questions
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
This route does not have any notably tricky sections. Most of the drive from Tallahassee, FL to San Antonio, FL is straightforward, with well-signed roads and simple exits.
Possible but tiring. At 4.6 hours each way, an in-and-out day trip would put you behind the wheel for 9.2 hours — manageable with a long break at San Antonio, FL, but most travelers stay overnight.
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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