Primanti Bros. Restaurant and Bar
Near the end, right off the route
Pittsburgh, Pennsylvania
Hours: 10:30 am–12 pm
+14122611599
Visit websiteCompiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
5h 31m
Distance
266.7 mi
429 km
Drive Score
10/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$44
one way
EV Charging
Good
7 stations
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Towanda, PA
Haneul Trac
Pittsburgh, PA
Wikimedia Commons
This 266.7-mile journey from Towanda, PA to Pittsburgh, PA takes approximately 5 hours and 31 minutes, making it a manageable one-day road trip. You'll navigate primarily via the William Penn Highway, Keystone Shortway, and US 220, with about 41% of the drive on highways. The estimated fuel cost for this trip is around $44. It's a mixed drive that can be completed in a single day, allowing for flexibility in your departure time. The route traverses within the Northeast region of Pennsylvania, offering a straightforward path across the state.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
133.4 miles from Towanda, PA
A natural place for your longest stop of the day , about 2h 35m into the drive .
| Road | Distance | Duration |
|---|---|---|
| William Penn Highway | 61.2 mi | 1h 25m |
| Keystone Shortway | 50.6 mi | 54m |
| US 220 | 48.5 mi | 55m |
| I 99 | 33.8 mi | 36m |
| Jacksonville Road | 24.2 mi | 28m |
| Penn-Lincoln Parkway East | 13.5 mi | 18m |
| Admiral Peary Highway | 13.4 mi | 19m |
| I 180 | 12 mi | 13m |
Step-by-step road directions between Towanda, PA and Pittsburgh, PA.
Start on Park Street
Turn right onto John B Merrill Parkway
Turn left onto South Main Street
At end of road, turn left onto US 220
Continue on PA 405
Continue on PA 405
Take the ramp
Merge onto I 180
Take the exit
Merge onto I 80
Take the exit
Turn left onto US 220; PA 26
Keep slight left at fork onto I 99; US 220
Take the exit
Continue on this road
Continue on US 22
Continue on US 22
Continue on US 22
Keep slight right at fork onto I 376; US 22
Take the exit
Turn straight onto Second Avenue
At end of road, turn right onto Ross Street
Turn left onto Fifth Avenue
Turn right onto Grant Street
Arrive at destination
For this 5-hour, 31-minute drive, consider an early morning departure to maximize your daylight hours and allow for a relaxed pace. With only one recommended stop, you have plenty of flexibility. Keep an eye on your fuel levels, especially during the 61.2-mile stretch on the William Penn Highway, and plan your refueling accordingly. This trip is well-suited for a single day, so you can depart when it's most convenient for you, perhaps after a hearty breakfast in Towanda.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 59 miles or 1h 12m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 133.4 miles or 2h 35m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 20m
Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.
Open the route before leaving Towanda, PA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Towanda, PA
This is one driving day of about 266.7 miles and 5h 31m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
133 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 59 miles helps settle the day before fatigue starts building.
The midpoint is around 133.4 miles from Towanda, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before William Penn Highway if your tank is already low. That segment runs about 61.2 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
Pittsburgh, Pennsylvania
Near the end, right off the route
Hours: 10:30 am–12 pm
+14122611599
Kiku Japanese Restaurant
Pittsburgh, Pennsylvania
Grand Concourse
Pittsburgh, Pennsylvania
Near the end, right off the route
Pittsburgh, Pennsylvania
Hours: 10:30 am–12 pm
+14122611599
Visit websiteNear the end, right off the route
Pittsburgh, Pennsylvania
Hours: 12–2 pm
+14127653200
Visit websiteNear the end, right off the route
Pittsburgh, Pennsylvania
Hours: 11:30 am–9:30 pm
+14122611717
Visit websiteNear the end, right off the route
Pittsburgh, Pennsylvania
Hours: 8 am–12 pm
+14122632142
Visit websiteNear the end, right off the route
Pittsburgh, Pennsylvania
Hours: 8 am–5 pm
+14123811822
Near the end, short detour
Pittsburgh, Pennsylvania
Hours: 5:30 pm–2 am
+14123816199
Visit websiteNear the end, short detour
Pittsburgh, Pennsylvania
Hours: 4–9:30 pm
+14124888708
Visit websiteNear the end, short detour
Pittsburgh, Pennsylvania
Hours: 5–9 pm
+14124813336
Visit websiteNear the end, ~12 min detour
Pittsburgh, PA
Hours: 7 am–9 pm
+14125631220
Visit websiteNear the end, ~9 min detour
Pittsburgh, Pennsylvania
Hours: Open 24 hours
Near the end, ~10 min detour
Monroeville, Pennsylvania
Hours: Open 24 hours
+18887584389
Visit websiteNear the end, ~9 min detour
Pittsburgh, Pennsylvania
Hours: Open 24 hours
Visit websiteNear the end, ~10 min detour
Pittsburgh, Pennsylvania
Hours: Open 24 hours
Near the end, ~10 min detour
Monroeville, Pennsylvania
Hours: Open 24 hours
+18887584389
Visit websiteNear the end, ~12 min detour
Castle Shannon, Pennsylvania
Hours: 9 am–8 pm
+18887174544
Visit websiteNear the end, ~12 min detour
Monroeville, Pennsylvania
Hours: 8 am–5 pm
+18887584389
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 118.1 and 266.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the exit toward I 99 South, US 220 South, PA 26: Bellefonte
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Keep slight left at fork onto I 99; US 220 toward I 99 South, US 220 South: Port Matilda, Altoona
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight right at fork onto I 376; US 22 / Penn-Lincoln Parkway East toward I 376 West, US 22 West: Pittsburgh
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward Second Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Turn right onto Grant Street
Lane positioning matters here
Regular Gas
$44.22 one way
$88.43 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.61 | $48.43 | $96.85 |
| premium | $4.93 | $51.72 | $103.45 |
| diesel | $5.61 | $58.88 | $117.77 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$44
Meals
$25–$50
Total
$69–$94
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 93.3 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $28 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 80 | 0 | $28.00 | $12.80 |
| Efficient EV | 66.7 | 0 | $23.34 | $10.67 |
| EV Truck/SUV | 106.7 | 1 | $37.34 | $17.07 |
Gas CO2
93 kg
EV CO2
31 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Towanda on Saturday
Local time
2:45 PM
EDT
Current temp
41°F
Unavailable
Destination
Afternoon in Pittsburgh on Saturday
Local time
2:45 PM
EDT
Current temp
49°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
The drive offers a varied experience, blending highway stretches with more traditional road travel. With 41% of the route on highways, you'll encounter periods of faster driving, interspersed with sections on the William Penn Highway and US 220. The longest uninterrupted stretch spans 61.2 miles on the William Penn Highway, providing a significant period of consistent travel. This mixed profile means you'll experience different driving dynamics throughout the 5.5-hour journey, keeping the experience engaging.
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 118.1 miles in.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 266.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 118.1 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 142.6 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 252.4 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Towanda, PA and Pittsburgh, PA, road signs point toward Altoona and Hollidaysburg.
Altoona
Hollidaysburg
The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 5h 31m. Total distance: 266.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 31m drive, comfortable solo distance.
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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