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Trip from Twin Lakes, WI to La Crosse, WI

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards

Drive Time

4h 22m

Distance

227 mi

365 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$35

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
4h 9m ★
6 AM
4h 22m
8 AM
4h 49m
10 AM
4h 32m
12 PM
4h 29m
3 PM
4h 33m
5 PM
4h 48m
8 PM
4h 14m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Twin Lakes, WI, WI

Twin Lakes, WI

Tom Fisk

city in and county seat of La Crosse County, Wisconsin, United States

La Crosse, WI

Wikimedia Commons

Trip Overview

The drive from Twin Lakes, WI to La Crosse, WI covers 227 miles and takes about 4h 22m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on I 90, I 39, US 12 for much of the mileage, and the overall profile is mostly highway. The longest uninterrupted segment is about 102.6 miles on I 90. At current regular gas prices, budget about $35.49 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

113.5 miles from Twin Lakes, WI

A natural place for your longest stop of the day , about 2h 12m into the drive .

Main Roads

Road Distance Duration
I 90 102.6 mi 1h 49m
I 39 65.8 mi 1h 10m
US 12 16.6 mi 18m
US 14 14.5 mi 19m
I 43 12.2 mi 13m
WI 16 4.9 mi 8m
Richmond Road 2 mi 3m
Lance Drive 1.6 mi 2m
Longest stretch: I 90 — 102.6 mi, about 1h 49m

Turn-by-Turn Driving Directions

Step-by-step road directions between Twin Lakes, WI and La Crosse, WI.

1

Start on CTH EM; CTH Z

399 ft · 16 sec · South Lake Avenue
2

Turn left onto CTH Z

0.3 mi · 27 sec · East Main Street
3

Continue on CTH O

1.6 mi · 2 min · Lance Drive
4

Continue on CTH O; CTH P

2.0 mi · 3 min · Richmond Road
5

Turn right onto 125th Street

0.3 mi · 39 sec · 125th Street
6

Continue on South Road

0.5 mi · 1 min · South Road
7

Turn right onto US 12

359 ft · 6 sec · US 12
8

Take the exit onto US 12

17 mi · 18 min · US 12
9

Take the exit

0.2 mi · 23 sec
Exit 321 Toward I 43, CTH NN: Beloit, Milwaukee Use the slight right lane.
10

Keep slight left at fork

0.4 mi · 56 sec
Toward I 43: Milwaukee, Beloit
11

Keep slight left at fork

0.2 mi · 31 sec
12

Keep slight right at fork

0.2 mi · 31 sec
Toward I 43 South: Delavan, Beloit
13

Merge onto I 43

12 mi · 13 min · I 43
Use the straight / slight right lanes.
14

Take the exit

0.3 mi · 34 sec
Exit 15 Toward US 14: Darien, Janesville Use the slight right lane.
15

Keep slight right at fork

121 ft · 3 sec
16

Merge onto US 14

3.3 mi · 4 min · US 14
17

Turn left onto US 14; WI 11

11 mi · 15 min · US 14; WI 11
18

Turn left onto WI 11

1.5 mi · 2 min · East Racine Street
19

Enter roundabout

10 ft · 0 sec
Toward I-90 WEST, I-39 NORTH: Madison
20

Continue

0.3 mi · 17 sec
Toward I-90 WEST, I-39 NORTH: Madison
21

Merge onto I 39; I 90

66 mi · 1 hr 10 min · I 39; I 90
Use the straight / slight left lanes.
22

Keep slight left at fork onto I 90; I 94

63 mi · 1 hr 8 min · I 90; I 94
Use the straight lane.
23

Keep slight left at fork onto I 90

39 mi · 41 min · I 90
Exit 45 Toward I 90 West: Tomah, La Crosse
24

Take the exit

0.3 mi · 41 sec
Exit 5 Toward WI 16: La Crosse, Onalaska
25

At end of road, turn left onto WI 16

4.9 mi · 8 min · WI 16
26

Continue on Losey Boulevard North

0.5 mi · 1 min · Losey Boulevard North
27

Turn right onto CTH F

0.7 mi · 1 min · Main Street
28

Turn left onto 16th Street South

0.8 mi · 2 min · 16th Street South
29

Turn right onto Johnson Street

0.3 mi · 1 min · Johnson Street
30

At end of road, turn right onto WI 35

326 ft · 11 sec · West Avenue South
31

Arrive at destination

WI 35

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 113.5 miles from Twin Lakes, WI, or about 2h 12m into the drive.
The longest continuous stretch on this route runs about 102.6 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 50 miles or 1h 4m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 113.5 miles or 2h 12m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 30m

Traffic, exits, and arrival timing usually matter more near La Crosse, WI than in the middle of the route.

Before You Leave

+

Open the route before leaving Twin Lakes, WI so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Twin Lakes, WI

This is one driving day of about 227 miles and 4h 22m.

Your first comfortable stop window is around 50 miles from Twin Lakes, WI.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 90 for about 102.6 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

reservoir on the Wisconsin River in Sauk and Columbia counties in Wisconsin, United States

Mid-route town

Meal stop

Lake Wisconsin, WI

114 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Lake Wisconsin, WI to La Crosse, WI

125.8 mi · 2h 31m

Pacing Suggestions

Harlem, IL

Fuel and coffee

A short stop after about 50 miles helps settle the day before fatigue starts building.

Lake Wisconsin, WI

Meal break

The midpoint is around 113.5 miles from Twin Lakes, WI, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 90 if your tank is already low. That segment runs about 102.6 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 24

5 decision points cluster between mile 21.2 and 180.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

8
21.2 mi into trip | ~27m in

Take the exit toward I 43, CTH NN: Beloit, Milwaukee

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 321 Toward I 43, CTH NN: Beloit, Milwaukee
6
21.4 mi into trip | ~27m in

Keep slight left at fork toward I 43: Milwaukee, Beloit

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 43: Milwaukee, Beloit
7
22.1 mi into trip | ~28m in

Keep slight right at fork toward I 43 South: Delavan, Beloit

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 43 South: Delavan, Beloit
8
34.5 mi into trip | ~42m in

Take the exit toward US 14: Darien, Janesville

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 15 Toward US 14: Darien, Janesville
7
180.3 mi into trip | ~3h 24m in | I 90

Keep slight left at fork onto I 90 toward I 90 West: Tomah, La Crosse

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Exit 45 Toward I 90 West: Tomah, La Crosse

Fuel & Cost

Regular Gas

$35.49 one way

$70.98 round trip

$3.97/gal 25.4 MPG avg 79 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $38.97 $77.93
premium $4.89 $43.68 $87.37
diesel $5.61 $50.12 $100.24

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$35

Meals

$25–$50

Total

$60–$85

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 79.4 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $24 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 68.1 0 $23.83 $10.90
Efficient EV 56.8 0 $19.86 $9.08
EV Truck/SUV 90.8 1 $31.78 $14.53

Gas CO2

79 kg

EV CO2

27 kg (66% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 16, 2026

Origin

Twin Lakes, WI

Afternoon in Twin Lakes on Saturday

Local time

2:21 PM

CDT

Current temp

47°F

Unavailable

Live forecast

Destination

La Crosse, WI

Afternoon in La Crosse on Saturday

Local time

2:21 PM

CDT

Current temp

75°F

Sunny

SW 2 mph 0% chance Live forecast

Flood Warning

Flood Warning issued April 16 at 4:45PM CDT until April 19 at 1:27AM CDT by NWS La Crosse WI

Flood Watch

Flood Watch issued April 16 at 3:11PM CDT until April 18 at 7:00AM CDT by NWS Milwaukee/Sullivan WI

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

28 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 22m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Ice Age National Scenic Trail

Ice Age National Scenic Trail

National Scenic Trail

The Ice Age National Scenic Trail spans 1,200 miles, traverses some of Wisconsin's finest geologic and glacial features, and passes through the ancestral lands of 15 Tribes. The Trail is built, manage...

25 mi from route ~63 min detour Free near mile 148.7
Caution: Averill–Kelly Creek Wilderness Segment — Dangerous Ford at New Wood River
Caution: Skunk and Foster Lakes Segment — Storm Damage
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

227 mi in 4h 22m, mostly highway — 102.6 mi of that is on I 90.

95% highway — fuel and pacing are the main things to plan.
31 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 102.6 mi on I 90.

How Hard Is This Drive?

9/10

This is a straightforward highway drive that stays mostly on I 90 and I 39. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 21.2 miles in.

Driving Effort 9/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 24 significant decision points across 227 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 21.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 21.4 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 22.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Twin Lakes, WI and La Crosse, WI, road signs point toward Cth Nn: Beloit, Milwaukee, Beloit and Janesville.

Cth Nn: Beloit

21.2 mi in | ~27m

Milwaukee

21.2 mi in | ~27m

Beloit

21.4 mi in | ~27m

Janesville

34.5 mi in | ~42m

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 4h 22m. Total distance: 227 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

4h 22m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (95%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 102.6 miles on I 90. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at La Crosse, WI before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 21.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 21.4 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 22.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.

Yes — Ice Age National Scenic Trail. See the National Parks section for detour distances and tips on detours.

Possible but tiring. At 4.4 hours each way, an in-and-out day trip would put you behind the wheel for 8.7 hours — manageable with a long break at La Crosse, WI, but most travelers stay overnight.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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