The drive from Weatherford, TX to Amarillo, TX covers 324.8 miles and takes about 6h 9m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US Highway 287, US 281, US Highway 287 East for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 75.4 miles on US Highway 287.
At current regular gas prices, budget about $49.08 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
162.4 miles from Weatherford, TX
A natural place for your longest stop of the day
, about 3h 13m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 9m. Total distance: 324.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 9m drive, plan rest stops for pacing.
Drive Character
This is a 6h 9m highway drive covering 324.8 miles, with most of the trip on US Highway 287 and US 281. The longest continuous stretch is about 75.4 miles on US Highway 287.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 32 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US Highway 287 is the longest continuous segment at about 75.4 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on US Highway 287 and US 281. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 1 miles in near FM 920 / West 4th Street.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 8 significant decision points across 324.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 1 miles (FM 920 / West 4th Street): Navigation decision point; at 102.9 miles (US 287 / Northwest Freeway): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 315 miles (East Interstate Drive): Highway fork - watch signs carefully.
Critical Maneuvers
5 of 8 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
4
1 mi into trip|~1m in|FM 920 / West 4th Street
Turn left onto FM 920 / West 4th Street
Navigation decision point
9
102.9 mi into trip|~2h 11m in|US 287 / Northwest Freeway
Keep slight left at fork onto US 287 / Northwest Freeway toward US 287 North: Vernon, Amarillo
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / straight lanes.
Exit 3A
Toward US 287 North: Vernon, Amarillo
5
315 mi into trip|~5h 56m in|East Interstate Drive
Keep slight right at fork onto East Interstate Drive toward East 3rd Avenue
Highway fork - watch signs carefully
Toward East 3rd Avenue
4
315.1 mi into trip|~5h 56m in|Southeast 3rd Avenue
Keep slight right at fork onto Southeast 3rd Avenue
Highway fork - watch signs carefully
5
319.2 mi into trip|~6h 2m in
Take the exit toward US 60, I 40 Business: Amarillo Boulevard
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 60, I 40 Business: Amarillo Boulevard
Main Roads
Road
Distance
Duration
US Highway 287
75.4 mi
1h 17m
US 281
51.7 mi
59m
US Highway 287 East
40.5 mi
42m
East 11th Street
28.7 mi
32m
TX 199
27.2 mi
31m
Boykin Drive
26.2 mi
28m
US Highway 287 West
25.7 mi
26m
Farm-to-Market Road 920
17.1 mi
30m
Longest stretch:
US Highway 287
— 75.4 mi, about 1h 17m
Turn-by-Turn Driving Directions
Step-by-step road directions between Weatherford, TX and Amarillo, TX.
1
Start on FM 51
1.0 mi·1 min·North Main Street
2
Turn left onto FM 920
0.4 mi·48 sec·West 4th Street
3
Continue on FM 920
1.3 mi·2 min·Peaster Highway
4
Continue on FM 920
17 mi·30 min·Farm-to-Market Road 920
5
Turn left onto TX 199
27 mi·31 min·TX 199
6
Continue on US 281; TX 114
52 mi·59 min·US 281; TX 114
7
Merge onto US 82; US 281; US 287
0.9 mi·1 min·Central East Freeway
8
Continue on US 281; US 287
0.8 mi·58 sec·Lloyd Ruby Overpass
9
Continue on US 277; US 281; US 287
2.4 mi·3 min·Central Freeway
Use the straight lane.
10
Keep slight left at fork onto US 287
5.3 mi·5 min·Northwest Freeway
Exit 3AToward US 287 North: Vernon, AmarilloUse the slight left / straight lanes.
11
Continue on US 287
40 mi·42 min·US Highway 287 East
Use the straight / left / right lanes.
12
Continue on US 70; US 183; US 287
4.1 mi·4 min·Martin Luther King Jr Memorial Highway
Use the straight / slight right lanes.
13
Continue on US 287
26 mi·26 min·US Highway 287 West
Use the straight lane.
14
Continue on US 287
29 mi·32 min·East 11th Street
15
Continue on US 287
2.8 mi·3 min·Avenue F Northeast
16
Continue on US 287
14 mi·14 min·US Highway 287
17
Continue on US 287
0.7 mi·1 min·Burnett Street
18
Continue on US 287
14 mi·13 min·US Highway 287
19
Turn straight onto US 287
26 mi·28 min·Boykin Drive
20
Continue on US 287
1.6 mi·1 min·East 2nd Street
21
Continue on US 287
28 mi·28 min·US Highway 287
22
Continue on US 287; FM 1151
1.1 mi·2 min·East 1st Street
23
Continue on US 287
20 mi·20 min·US Highway 287
24
Keep slight right at fork onto East Interstate Drive
329 ft·8 sec·East Interstate Drive
Toward East 3rd Avenue
25
Keep slight right at fork onto Southeast 3rd Avenue
2.6 mi·3 min·Southeast 3rd Avenue
26
Take the ramp
0.2 mi·26 sec
27
Merge onto Loop 335
1.3 mi·1 min·North Lakeside Drive
28
Take the exit
0.3 mi·46 sec
Toward US 60, I 40 Business: Amarillo Boulevard
29
Turn left onto I 40 Business; US Historic 66; US 60
4.4 mi·5 min·East Amarillo Boulevard
30
Continue on I 40 Business; Original US Route 66; US 60
0.9 mi·1 min·I 40 Business; Original US Route 66; US 60
31
Continue on I 40 Business
0.1 mi·17 sec·East Amarillo Boulevard
32
Arrive at destination
I 40 Business; Original US Route 66; US 60
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 162.4 miles from Weatherford, TX, or about 3h 13m into the drive.
The longest continuous stretch on this route runs about 75.4 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 71 miles or 1h 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 162.4 miles or 3h 13m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 6m
Traffic, exits, and arrival timing usually matter more near Amarillo, TX than in the middle of the route.
Before You Leave
+
Open the route before leaving Weatherford, TX so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Weatherford, TX
This is one driving day of about 324.8 miles and 6h 9m.
Your first comfortable stop window is around 71 miles from Weatherford, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US Highway 287 for about 75.4 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 162.4 mi from Weatherford, TX
· 3h 13m into the drive
The midpoint is around 162.4 miles from Weatherford, TX, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before US Highway 287 if your tank is already low. That segment runs about 75.4 miles.
Arriving in Amarillo, TX
The final approach into Amarillo, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Amarillo, TX.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Alibates Flint Quarries National Monument
National Monument
13,000 years ago, Alibates Flint was used by mammoth hunters as a source of flint for tools. Learn how important this site was to the survival, commerce, and culture of the people of the High Plains.
26 mi from route
~66 min detour
Free
near mile 324.8
Set within the wide‑open Texas Plains, Lake Meredith National Recreation Area offers a peaceful retreat in the heart of rugged grasslands. Over thousands of years, the Canadian River carved dramatic 2...
29 mi from route
~72 min detour
Free
near mile 324.8
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$49.08 one way
$98.16 round trip
$3.84/gal25.4 MPG avg114 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.20
$53.72
$107.44
premium
$4.54
$57.99
$115.98
diesel
$5.61
$71.71
$143.42
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$49
Meals
$25–$50
Total
$74–$99
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 113.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $34 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
97.4
1
$34.10
$15.59
Efficient EV
81.2
0
$28.42
$12.99
EV Truck/SUV
129.9
1
$45.47
$20.79
Gas CO2
114 kg
EV CO2
38 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Weatherford, TX
Afternoon
in Weatherford on Friday
Local time
2:14 PM
CDT
Current temp
71°F
Unavailable
Live forecast
Destination
Amarillo, TX
Afternoon
in Amarillo on Friday
Local time
2:14 PM
CDT
Current temp
84°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
13 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 9m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Weatherford, TX to Amarillo, TX covers 324.8 miles and takes about 6h 9m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US Highway 287, US 281, US Highway 287 East. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 162.4 miles from Weatherford, TX. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $49.08 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 8 significant decision points across 324.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 1 miles (FM 920 / West 4th Street): Navigation decision point; at 102.9 miles (US 287 / Northwest Freeway): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 315 miles (East Interstate Drive): Highway fork - watch signs carefully.
The route from Weatherford, TX to Amarillo, TX does not surface many named destination signs beyond the main corridor.
Yes. Nearby national parks include Alibates Flint Quarries National Monument and Lake Meredith National Recreation Area.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
