De Soto National Memorial
National Memorial
In May 1539, Conquistador Hernando de Soto’s army of soldiers, hired mercenaries, craftsmen, and clergy made landfall in Tampa Bay. They were met with fierce resistance of indigenous people protecting...
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Drive Time
5h 43m
Distance
304.3 mi
490 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$48
one way
EV Charging
None
0 DC fast
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Wellborn, FL
Larry Milligan
Cape Coral, FL
Wikimedia Commons
This 304.3-mile drive from Wellborn, FL to Cape Coral, FL will take you about 5 hours and 43 minutes. Primarily utilizing I-75, with some sections of Tamiami Trail and US 90, this route is a highway-focused journey. With a fuel cost estimated at $48, it's a manageable single-day trip, though you could certainly break it up if you prefer a more relaxed pace. The drive keeps you within the state of Florida, transitioning from the northern part of the state down towards the southwestern coast. It's a straightforward trip designed for efficient travel.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
152.1 miles from Wellborn, FL
A natural place for your longest stop of the day , about 2h 46m into the drive .
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Expect a predominantly highway experience on this route, with 92% of the journey taking place on main roads like I-75. You'll encounter a significant longest stretch of 269.7 miles on I-75, suggesting long periods of consistent speed. While the profile is highway-focused, the inclusion of Tamiami Trail and US 90 may offer slight variations in scenery and speed as you transition between major arteries. This drive is built for covering distance, so prepare for a predominantly high-speed transit.
This is a straightforward highway drive that stays mostly on I 75 and Tamiami Trail. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 163 miles in near I 75.
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 12 significant decision points across 304.3 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 163 miles (I 75): Highway fork - watch signs carefully. Lane positioning matters here; at 237.3 miles (I 75): Highway fork - watch signs carefully. Lane positioning matters here; at 279.5 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Keep slight left at fork onto I 75 toward South I 75: Naples
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight left at fork onto I 75
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward CR 762: North Fort Myers, Cape Coral
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Keep slight right at fork toward CR 762 West, to US 41
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Turn right onto CR 867A / Del Prado Boulevard North
Lane positioning matters here
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Wellborn, FL and Cape Coral, FL, road signs point toward Cr 762: North Fort Myers, Cr 762 West and To Us 41.
Cr 762: North Fort Myers
Cr 762 West
To Us 41
| Road | Distance | Duration |
|---|---|---|
| I 75 | 269.7 mi | 4h 49m |
| Tamiami Trail | 10.4 mi | 12m |
| US 90 | 8.8 mi | 12m |
| Del Prado Boulevard North | 6.5 mi | 10m |
| Del Prado Boulevard South | 6.2 mi | 12m |
| Tuckers Grade | 0.9 mi | 1m |
| CR 137 | 0.7 mi | <1m |
| Cape Coral Parkway East | 0.3 mi | <1m |
Step-by-step road directions between Wellborn, FL and Cape Coral, FL.
Start on 6th Avenue
Turn left onto CR 137
Turn left onto US 90
Take the ramp
Merge onto I 75
Keep slight left at fork onto I 75
Keep slight left at fork onto I 75
Take the exit
Keep slight right at fork
Turn straight onto CR 762
Turn left onto US 41
Turn right onto CR 867A
Continue on CR 867A
Turn right onto Cape Coral Parkway East
Turn right
Arrive at destination
For this 5-hour and 43-minute drive, consider an early morning departure from Wellborn to maximize your daylight hours and avoid potential afternoon traffic. With one main stop suggested, you can plan to refuel and stretch your legs about midway, perhaps around the longest stretch on I-75. The estimated fuel cost of $48 makes budgeting straightforward. Since this is a single-day trip, you have the flexibility to push through or take additional brief breaks as needed, but be mindful of the long continuous highway stretches.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 29m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 152.1 miles or 2h 46m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 31m
Traffic, exits, and arrival timing usually matter more near Cape Coral, FL than in the middle of the route.
Open the route before leaving Wellborn, FL so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Wellborn, FL
This is one driving day of about 304.3 miles and 5h 43m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 152.1 mi from Wellborn, FL · 2h 46m into the drive
Mid-route town
Meal stop
152 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 152.1 miles from Wellborn, FL, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 75 if your tank is already low. That segment runs about 269.7 miles.
The final approach into Cape Coral, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Cape Coral, FL.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Worth a detour if your schedule allows.
National Memorial
In May 1539, Conquistador Hernando de Soto’s army of soldiers, hired mercenaries, craftsmen, and clergy made landfall in Tampa Bay. They were met with fierce resistance of indigenous people protecting...
Park data from the National Park Service API. Alerts update every 2 hours.
Regular Gas
$48.44 one way
$96.87 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.40 | $52.69 | $105.38 |
| premium | $4.72 | $56.58 | $113.17 |
| diesel | $5.61 | $67.19 | $134.37 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$48
Meals
$25–$50
Total
$73–$98
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 106.5 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $32 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 91.3 | 1 | $31.95 | $14.61 |
| Efficient EV | 76.1 | 0 | $26.63 | $12.17 |
| EV Truck/SUV | 121.7 | 1 | $42.60 | $19.48 |
Gas CO2
106 kg
EV CO2
36 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Wellborn on Wednesday
Local time
2:27 AM
EDT
Current temp
61°F
Unavailable
Destination
Late night in Cape Coral on Wednesday
Local time
2:27 AM
EDT
Current temp
64°F
Mostly Clear
Rip Current Statement
Rip Current Statement issued April 14 at 4:28PM EDT until April 16 at 8:00PM EDT by NWS Miami FL
Rip Current Statement
Rip Current Statement issued April 14 at 12:29PM EDT until April 15 at 2:00AM EDT by NWS Tallahassee FL
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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