Origin
Wellsboro, PA
Evening in Wellsboro on Wednesday
Local time
8:41 PM
EDT
Current temp
41°F
Unavailable
Live forecast
Trip from Wellsboro, PA to Pittsburgh, PA
Last recalculated Apr 16, 2026
Drive Time
5h 7m
Distance
223.2 mi
359 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$37
one way
Best Time to Leave
4 AM
4h 54m
★
6 AM
5h 7m
8 AM
5h 34m
10 AM
5h 17m
12 PM
5h 14m
3 PM
5h 18m
5 PM
5h 33m
8 PM
4h 59m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Wellsboro, PA
Michael Taccetta
Pittsburgh, PA
Wikimedia Commons
Trip Overview
This 223.2-mile journey from Wellsboro, PA to Pittsburgh, PA is a solid day trip, estimated to take around 5 hours and 7 minutes of driving time. The route primarily utilizes William Penn Highway, Route 287, and I-99, with 39% of the drive on highways. You can expect a fuel cost of approximately $37 for this trip. Given the duration and distance, it’s comfortably manageable as a single-day adventure, allowing for flexibility in your departure time and a single planned stop. This drive offers a mixed experience, transitioning between different road types as you head west across Pennsylvania.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
111.6 miles from Wellsboro, PA
A natural place for your longest stop of the day , about 2h 36m into the drive .
Drive Character
The drive presents a mixed bag of road types, with a 39% share of highway driving. You'll experience stretches on the historic William Penn Highway, which can be more engaging, and also navigate parts of Route 287 and the interstate. The longest uninterrupted stretch you’ll encounter is 61.2 miles on the William Penn Highway, offering a solid period of consistent travel. This variety means the road's character will shift throughout your journey, moving from potentially more rural or historic roads to faster-paced interstate sections as you approach Pittsburgh.
Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 27 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
William Penn Highway is the longest continuous segment at about 61.2 miles.
How Hard Is This Drive?
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 74.6 miles in.
Route Complexity
7/10
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 14 significant decision points across 223.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 74.6 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 99.1 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 208.9 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 14 key pointsThese are the spots where you need to pay the most attention. Preview them before you drive.
6
74.6 mi into trip
|
~1h 53m in
Take the exit toward I 99 South, US 220 South, PA 26: Bellefonte
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 161
Toward I 99 South, US 220 South, PA 26: Bellefo...
6
99.1 mi into trip
|
~2h 22m in
|
I 99; US 220
Keep slight left at fork onto I 99; US 220 toward I 99 South, US 220 South: Port Matilda, Altoona
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 99 South, US 220 South: Port Matilda,...
8
208.9 mi into trip
|
~4h 46m in
|
I 376; US 22 / Penn-Lincoln Parkway East
Keep slight right at fork onto I 376; US 22 / Penn-Lincoln Parkway East toward I 376 West, US 22 West: Pittsburgh
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left lane.
Toward I 376 West, US 22 West: Pittsburgh
7
222.4 mi into trip
|
~5h 4m in
Take the exit toward Second Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 71B
Toward Second Avenue
7
223.1 mi into trip
|
~5h 6m in
|
Grant Street
Turn right onto Grant Street
Lane positioning matters here
Use the right lane.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Wellsboro, PA and Pittsburgh, PA, road signs point toward Altoona and Hollidaysburg.
Altoona
99.1 mi in
|
~2h 22m
|
via I 99; US 220
Hollidaysburg
132.9 mi in
|
~2h 59m
Main Roads
| Road | Distance | Duration |
|---|---|---|
| William Penn Highway | 61.2 mi | 1h 25m |
| Route 287 | 35.2 mi | 1h 1m |
| I 99 | 33.8 mi | 36m |
| Jacksonville Road | 24.2 mi | 28m |
| Appalachian Thruway | 15.9 mi | 18m |
| Penn-Lincoln Parkway East | 13.5 mi | 18m |
| Admiral Peary Highway | 13.4 mi | 19m |
| Keystone Shortway | 11.8 mi | 12m |
Longest stretch:
William Penn Highway
— 61.2 mi, about 1h 25m
Turn-by-Turn Driving Directions
Step-by-step road directions between Wellsboro, PA and Pittsburgh, PA.
1
Start on PA 660
0.1 mi
·
19 sec
·
Main Street
2
Turn left onto PA 287
1.2 mi
·
2 min
·
Central Avenue
3
Continue on PA 287
11 mi
·
18 min
·
Route 287
4
Continue on PA 287; PA 414
25 mi
·
43 min
·
Route 287
5
Continue on PA 287; PA 973
3.6 mi
·
6 min
·
PA 287; PA 973
6
Turn right onto US 220
1.7 mi
·
2 min
·
Susquehanna Beltway
7
Continue on US 220
16 mi
·
18 min
·
Appalachian Thruway
8
Take the exit
0.3 mi
·
51 sec
Exit 107
Toward PA 477: Salona
9
Turn right onto PA 477
439 ft
·
10 sec
·
Long Run Road
10
At end of road, turn left onto PA 64
4.4 mi
·
7 min
·
Nittany Valley Drive
11
Take the ramp
0.4 mi
·
53 sec
12
Merge onto I 80; US 220
12 mi
·
12 min
·
Keystone Shortway
13
Take the exit
0.3 mi
·
53 sec
Exit 161
Toward I 99 South, US 220 South, PA 26: Bellefonte
14
Turn left onto US 220; PA 26
24 mi
·
28 min
·
Jacksonville Road
Use the straight lane.
15
Keep slight left at fork onto I 99; US 220
34 mi
·
36 min
·
I 99; US 220
Toward I 99 South, US 220 South: Port Matilda, Altoona
16
Take the exit
0.8 mi
·
1 min
Toward US 22: Ebensburg, Hollidaysburg
17
Continue on this road
0.5 mi
·
43 sec
·
this road
18
Continue on US 22
16 mi
·
19 min
·
William Penn Highway
19
Continue on US 22
13 mi
·
19 min
·
Admiral Peary Highway
Use the straight lane.
20
Continue on US 22
45 mi
·
1 hr 6 min
·
William Penn Highway
Use the straight / right lanes.
21
Keep slight right at fork onto I 376; US 22
13 mi
·
18 min
·
Penn-Lincoln Parkway East
Toward I 376 West, US 22 West: Pittsburgh
Use the slight left lane.
22
Take the exit
0.2 mi
·
38 sec
Exit 71B
Toward Second Avenue
Use the straight / slight right lanes.
23
Turn straight onto Second Avenue
0.3 mi
·
41 sec
·
Second Avenue
24
At end of road, turn right onto Ross Street
0.2 mi
·
32 sec
·
Ross Street
25
Turn left onto Fifth Avenue
352 ft
·
10 sec
·
Fifth Avenue
26
Turn right onto Grant Street
513 ft
·
21 sec
·
Grant Street
Use the right lane.
27
Arrive at destination
Grant Street
Trip Plan
For this 5-hour drive, leaving Wellsboro in the morning will allow you to arrive in Pittsburgh with ample time to settle in. With only one recommended stop, plan for a break around the halfway point or when you feel ready. The estimated fuel cost of $37 is a good benchmark, but always keep an eye on your gauge, especially during the 61.2-mile stretch on William Penn Highway where services might be more spaced out. Since this is a feasible one-day trip, you have the advantage of flexibility; however, be mindful of potential traffic as you get closer to Pittsburgh, especially during peak hours.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 111.6 miles from Wellsboro, PA, or about 2h 36m into the drive.
The longest continuous stretch on this route runs about 61.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 49 miles or 1h 21m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 111.6 miles or 2h 36m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 8m
Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Wellsboro, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Wellsboro, PA
This is one driving day of about 223.2 miles and 5h 7m.
Your first comfortable stop window is around 49 miles from Wellsboro, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on William Penn Highway for about 61.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 111.6 mi from Wellsboro, PA · 2h 36m into the drive
Mid-route town
Meal stop
112 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 49 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 111.6 miles from Wellsboro, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before William Penn Highway if your tank is already low. That segment runs about 61.2 miles.
Arriving in Pittsburgh, PA
The final approach into Pittsburgh, PA usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Pittsburgh, PA.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$37.00 one way
$74.01 round trip
$4.21/gal
25.4 MPG avg
78 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.61 | $40.53 | $81.05 |
| premium | $4.93 | $43.29 | $86.57 |
| diesel | $5.61 | $49.28 | $98.56 |
Estimated Tolls: $1.11
Appalachian Thruway
(15.9 mi)
$1.11
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$37
Tolls
$1
Meals
$25–$50
Total
$63–$88
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 78.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 67 | 0 | $23.44 | $10.71 |
| Efficient EV | 55.8 | 0 | $19.53 | $8.93 |
| EV Truck/SUV | 89.3 | 1 | $31.25 | $14.28 |
Gas CO2
78 kg
EV CO2
26 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Pittsburgh, PA
Evening in Pittsburgh on Wednesday
Local time
8:41 PM
EDT
Current temp
49°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
8 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 7m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Wellsboro, PA to Pittsburgh, PA covers 223.2 miles and takes about 5h 7m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are William Penn Highway, Route 287, I 99. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 111.6 miles from Wellsboro, PA. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $37.00 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 14 significant decision points across 223.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 74.6 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 99.1 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 208.9 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Wellsboro, PA and Pittsburgh, PA, road signs point toward Altoona and Hollidaysburg.
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