The drive from Williston Highlands, FL to Port Saint Lucie, FL covers 222.8 miles and takes about 4h 13m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Florida's Turnpike, I 75, US 27 for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 165.2 miles on Florida's Turnpike.
At current regular gas prices, budget about $35.46 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
111.4 miles from Williston Highlands, FL
A natural place for your longest stop of the day
, about 2h 10m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h 13m. Total distance: 222.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
This is a 4h 13m highway drive covering 222.8 miles, with most of the trip on Florida's Turnpike and I 75. The longest continuous stretch is about 165.2 miles on Florida's Turnpike.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 14 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Florida's Turnpike is the longest continuous segment at about 165.2 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on Florida's Turnpike and I 75. There are only a few real navigation decisions along the way. The trickiest moment comes around 29 miles in.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 4h 13m drive. You will face about 11 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 29 miles: Exit ramp - move to the correct lane early; at 29.4 miles (I 75): Merge point - match speed before joining. Lane positioning matters here; at 54 miles (Florida's Turnpike): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 11 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
29 mi into trip|~41m in
Take the exit toward I 75 South: Tampa
Exit ramp - move to the correct lane early
Toward I 75 South: Tampa
5
29.4 mi into trip|~42m in|I 75
Merge onto I 75
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
8
54 mi into trip|~1h 8m in|Florida's Turnpike
Take the exit onto Florida's Turnpike toward Florida's Turnpike South, Orlando
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / straight lanes.
Exit 328
Toward Florida's Turnpike South, Orlando
6
220.3 mi into trip|~4h 8m in|FL 716 / Southwest Port Saint Lucie Boulevard
Turn right onto FL 716 / Southwest Port Saint Lucie Boulevard
Lane positioning matters here
Use the right lane.
6
221.1 mi into trip|~4h 10m in|CR 615 / Southeast Airoso Boulevard
Turn left onto CR 615 / Southeast Airoso Boulevard
Lane positioning matters here
Use the left / uturn lanes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Williston Highlands, FL and Port Saint Lucie, FL, road signs point toward Florida's Turnpike South and Orlando.
Florida's Turnpike South
54 mi in|~1h 8m|via Florida's Turnpike
Orlando
54 mi in|~1h 8m|via Florida's Turnpike
Main Roads
Road
Distance
Duration
Florida's Turnpike
165.2 mi
2h 57m
I 75
24.7 mi
26m
US 27
19 mi
23m
FL 121
7.9 mi
12m
Southeast Airoso Boulevard
1.6 mi
2m
East Levy Street
1.3 mi
3m
Southwest Port Saint Lucie Boulevard
0.8 mi
1m
Northeast 140th Avenue
0.6 mi
1m
Longest stretch:
Florida's Turnpike
— 165.2 mi, about 2h 57m
Turn-by-Turn Driving Directions
Step-by-step road directions between Williston Highlands, FL and Port Saint Lucie, FL.
1
Start on Northeast 6th Street
0.1 mi·35 sec·Northeast 6th Street
2
At end of road, turn right onto CR 316
0.6 mi·1 min·Northeast 140th Avenue
3
Turn left onto East Levy Street
1.3 mi·3 min·East Levy Street
4
Turn left onto FL 121
7.9 mi·12 min·FL 121
5
Turn right onto US 27
19 mi·23 min·US 27
6
Take the exit
0.4 mi·46 sec
Toward I 75 South: Tampa
7
Merge onto I 75
25 mi·26 min·I 75
Use the straight / slight right lanes.
8
Take the exit onto Florida's Turnpike
165 mi·2 hr 57 min·Florida's Turnpike
Exit 328Toward Florida's Turnpike South, OrlandoUse the slight left / straight lanes.
9
Take the exit
1.0 mi·2 min
Exit 142Toward Port Saint Lucie
10
Continue on Southwest Bayshore Boulevard
483 ft·15 sec·Southwest Bayshore Boulevard
11
Turn right onto FL 716
0.8 mi·1 min·Southwest Port Saint Lucie Boulevard
Use the right lane.
12
Turn left onto CR 615
1.6 mi·2 min·Southeast Airoso Boulevard
Use the left / uturn lanes.
13
Turn left onto Southwest Carter Avenue
215 ft·9 sec·Southwest Carter Avenue
14
Arrive at destination
Southwest Carter Avenue
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 111.4 miles from Williston Highlands, FL, or about 2h 10m into the drive.
The longest continuous stretch on this route runs about 165.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 49 miles or 1h 3m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 111.4 miles or 2h 10m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 26m
Traffic, exits, and arrival timing usually matter more near Port Saint Lucie, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Williston Highlands, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Williston Highlands, FL
This is one driving day of about 222.8 miles and 4h 13m.
Your first comfortable stop window is around 49 miles from Williston Highlands, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Florida's Turnpike for about 165.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 111.4 mi from Williston Highlands, FL
· 2h 10m into the drive
The midpoint is around 111.4 miles from Williston Highlands, FL, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before Florida's Turnpike if your tank is already low. That segment runs about 165.2 miles.
Arriving in Port Saint Lucie, FL
The final approach into Port Saint Lucie, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Port Saint Lucie, FL.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Nearby Places
Restaurants, cafes, gas stations and more along your route.
Top Coffee Stop
Piccolo Coffee Co.
4.8
★ ★ ★ ★ ★
Winter Garden, Florida
Around the midpoint, short detour
2.9 mi from route
~7 min detour
$1 to $10
mile 95.5
Place data sourced from public business listings. Hours and availability may vary.
Fuel & Cost
Regular Gas
$35.46 one way
$70.93 round trip
$4.04/gal25.4 MPG avg78 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.40
$38.58
$77.16
premium
$4.72
$41.43
$82.86
diesel
$5.61
$49.19
$98.38
Estimated Tolls: $11.56
Florida's Turnpike
(165.2 mi)$11.56
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$35
Tolls
$12
Meals
$25–$50
Total
$72–$97
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 78 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
66.8
0
$23.39
$10.69
Efficient EV
55.7
0
$19.50
$8.91
EV Truck/SUV
89.1
1
$31.19
$14.26
Gas CO2
78 kg
EV CO2
26 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 14, 2026
Origin
Williston Highlands, FL
Morning
in Williston Highlands on Saturday
Local time
10:42 AM
EDT
Current temp
56°F
Unavailable
Live forecast
Destination
Port Saint Lucie, FL
Morning
in Port Saint Lucie on Saturday
Local time
10:42 AM
EDT
Current temp
64°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
8 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 13m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Williston Highlands, FL to Port Saint Lucie, FL covers 222.8 miles and takes about 4h 13m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Florida's Turnpike, I 75, US 27. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 111.4 miles from Williston Highlands, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $35.46 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a straightforward 4h 13m drive. You will face about 11 decision points, but nothing that requires special attention if you follow navigation.
The main spots that need attention: at 29 miles: Exit ramp - move to the correct lane early; at 29.4 miles (I 75): Merge point - match speed before joining. Lane positioning matters here; at 54 miles (Florida's Turnpike): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Williston Highlands, FL and Port Saint Lucie, FL, road signs point toward Florida's Turnpike South and Orlando.
