Trip.ovh Logo
Trip.ovh

Trip from Affton, MO to Cape Girardeau, MO

Drive Time

2h 3m

Distance

107.7 mi

173 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$16

one way

EV Charging

Loading...

station data

Best Time to Leave

Save up to 26 min
4 AM
1h 55m ★
6 AM
2h 4m
8 AM
2h 21m
10 AM
2h 10m
12 PM
2h 8m
3 PM
2h 11m
5 PM
2h 20m
8 PM
1h 58m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly
Google Maps Waze Apple Maps
Download GPX
Downtown Affton, MO, MO

Affton, MO

Valeria Boltneva

Downtown Cape Girardeau, MO, MO

Cape Girardeau, MO

Craig Picariello

Trip Overview

If you are planning a quick getaway from the suburbs of Affton to the riverside city of Cape Girardeau, you are looking at a manageable 107.7-mile journey. Expect to spend approximately 2 hours and 3 minutes behind the wheel, making this an ideal candidate for a single-day trip. With a fuel budget of roughly $16, the drive is both efficient and budget-friendly. You will stay within the Midwest for the entire duration, transitioning between Missouri communities via major arterial roads. Whether you are heading out for business or a weekend visit, the route is straightforward enough that you won't need to worry about overnight logistics unless you have a packed itinerary at your destination.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

0 planned breaks

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

53.8 miles from Affton, MO

A natural place for your longest stop of the day , about 1h 1m into the drive .

Drive Character

This trip is defined by its efficiency, with 92% of your travel taking place on high-speed highways. You will spend the vast majority of your time—specifically 99.2 miles—cruising along I-55, which provides a consistent, high-capacity road surface. While the interstate dominates the experience, the final leg of the journey transitions into local transit via North Kingshighway and Broadway Street. This shift from a fast-paced interstate grind to local city streets signals your arrival in Cape Girardeau. It is a functional, highway-focused drive that prioritizes speed and directness over winding backroads, keeping your time behind the wheel predictable and steady.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 12 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 55 is the longest continuous segment at about 99.2 miles.

Elevation Profile

Mostly flat terrain

618 ft 416 ft

Total Climb

431 ft

Total Descent

309 ft

Highest Point

618 ft

~71.8 mi in

Elevation Range

202 ft

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on I 55 and North Kingshighway. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near MO 21 / Tesson Ferry Road.

Route Complexity 3/10

Easy - simple navigation with a manageable amount of wheel time

This is a straightforward 2h 3m drive. You will face about 8 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

The main spots that need attention: near the start (MO 21 / Tesson Ferry Road): Navigation decision point; at 0.5 miles (Reavis Road): Navigation decision point; at 2.3 miles (I 55): Merge point - match speed before joining. Lane positioning matters here.

Critical Maneuvers

5 of 8 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

4
0 mi into trip | ~0m in | MO 21 / Tesson Ferry Road

Turn left onto MO 21 / Tesson Ferry Road

Navigation decision point

4
0.5 mi into trip | ~1m in | Reavis Road

Turn left onto Reavis Road

Navigation decision point

5
2.3 mi into trip | ~5m in | I 55

Merge onto I 55

Merge point - match speed before joining. Lane positioning matters here

Use the none lane.
6
101.6 mi into trip | ~1h 52m in

Take the exit toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 99 Toward US 61, MO 34, I 55 Business: Cape Girard...
8
101.7 mi into trip | ~1h 53m in

Keep slight left at fork toward I 55 Business, US 61 South, MO 34 East: Cape Girardeau

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Exit 99 Toward I 55 Business, US 61 South, MO 34 East:...

Towns Along This Route

On the drive from Affton, MO to Cape Girardeau, MO, road signs begin pointing toward Jackson along the way.

Jackson

101.6 mi in | ~1h 52m

Main Roads

Road Distance Duration
I 55 99.2 mi 1h 47m
North Kingshighway 3.6 mi 6m
Broadway Street 2 mi 3m
Reavis Barracks Road 0.7 mi 1m
Reavis Road 0.5 mi 1m
Mackenzie Road 0.5 mi 1m
Tesson Ferry Road 0.5 mi 1m
Longest stretch: I 55 — 99.2 mi, about 1h 47m

Turn-by-Turn Driving Directions

Step-by-step road directions between Affton, MO and Cape Girardeau, MO.

1

Start on this road

119 ft · 16 sec · this road
2

Turn left onto MO 21

0.5 mi · 1 min · Tesson Ferry Road
3

Turn left onto Reavis Road

0.5 mi · 1 min · Reavis Road
4

Turn right onto Mackenzie Road

0.5 mi · 1 min · Mackenzie Road
5

Turn straight onto Reavis Barracks Road

0.7 mi · 1 min · Reavis Barracks Road
6

Take the ramp

0.2 mi · 14 sec
Toward I 55 South
7

Merge onto I 55

99 mi · 1 hr 47 min · I 55
Use the none lane.
8

Take the exit

0.2 mi · 17 sec
Exit 99 Toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson
9

Keep slight left at fork

0.3 mi · 28 sec
Exit 99 Toward I 55 Business, US 61 South, MO 34 East: Cape Girardeau
10

Continue on I 55 Bus; US 61; MO 34

3.6 mi · 6 min · North Kingshighway
Use the none lane.
11

Turn left onto Broadway Street

2.0 mi · 3 min · Broadway Street
12

Arrive at destination

Broadway Street

Trip Plan

Because this route is relatively short, you have plenty of flexibility regarding your departure time, though avoiding peak traffic hours is always a smart move. Since there are no designated stops required by the length of the trip, you can easily complete the 107.7 miles in one go. Keep in mind that your fuel costs will hover around $16, so checking your tank before leaving Affton is a good way to ensure a smooth, uninterrupted run. Given that the longest stretch of 99.2 miles is entirely on I-55, make sure you are comfortable with sustained highway speeds. If you find yourself needing a break, plan to stretch your legs once you transition off the interstate and onto the local roads leading into Cape Girardeau.

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 53.8 miles from Affton, MO, or about 1h 1m into the drive.
The longest continuous stretch on this route runs about 99.2 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 29m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 53.8 miles or 1h 1m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 1h 38m

Traffic, exits, and arrival timing usually matter more near Cape Girardeau, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Affton, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Affton, MO

This is one driving day of about 107.7 miles and 2h 3m.

Your first comfortable stop window is around 80 miles from Affton, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
You may only need one short stretch stop if conditions stay smooth.
The longest stretch is on I 55 for about 99.2 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 53.8 mi from Affton, MO · 1h 1m into the drive

Downtown Cahokia, IL, IL

Mid-route town

Meal stop

Cahokia, IL

54 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Campton, IL

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Cahokia, IL

Meal break

The midpoint is around 53.8 miles from Affton, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 55 if your tank is already low. That segment runs about 99.2 miles.

Arriving in Cape Girardeau, MO

The final approach into Cape Girardeau, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Cape Girardeau, MO.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$16.36 one way

$32.72 round trip

$3.86/gal 25.4 MPG avg 38 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.25 $18.03 $36.07
premium $4.80 $20.33 $40.66
diesel $5.64 $23.93 $47.85

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$16

Meals

$25–$50

Total

$41–$66

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 37.7 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $11 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 32.3 0 $11.31 $5.17
Efficient EV 26.9 0 $9.42 $4.31
EV Truck/SUV 43.1 0 $15.08 $6.89

Gas CO2

38 kg

EV CO2

13 kg (66% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 10 hours ago

Origin

Affton, MO

Afternoon in Affton on Sunday

Local time

3:31 PM

CDT

Current temp

61°F

Partly Cloudy

S 7 mph 2% chance Live forecast

Special Weather Statement

Special Weather Statement issued April 12 at 12:21AM CDT by NWS Paducah KY

Flood Warning

Flood Warning issued April 11 at 9:46PM CDT until April 18 at 1:00PM CDT by NWS St Louis MO

Destination

Cape Girardeau, MO

Afternoon in Cape Girardeau on Sunday

Local time

3:31 PM

CDT

Current temp

59°F

Partly Cloudy

S 7 mph 1% chance Live forecast

Special Weather Statement

Special Weather Statement issued April 12 at 12:21AM CDT by NWS Paducah KY

Flood Warning

Flood Warning issued April 11 at 9:46PM CDT until April 18 at 1:00PM CDT by NWS St Louis MO

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

2 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 3m on the road

The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Affton, MO to Cape Girardeau, MO covers 107.7 miles and takes about 2h 3m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 55, North Kingshighway, Broadway Street. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 53.8 miles from Affton, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $16.36 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a straightforward 2h 3m drive. You will face about 8 decision points, but nothing that requires special attention if you follow navigation.
The main spots that need attention: near the start (MO 21 / Tesson Ferry Road): Navigation decision point; at 0.5 miles (Reavis Road): Navigation decision point; at 2.3 miles (I 55): Merge point - match speed before joining. Lane positioning matters here.
On the drive from Affton, MO to Cape Girardeau, MO, road signs begin pointing toward Jackson along the way.
Mostly flat terrain. The route ranges from 416 ft to 618 ft elevation with about 431 ft of total climbing.

Was this route helpful?

Thanks for your feedback!

Your tip has been submitted. Thanks!

/500

Explore More

Return Trip

Cape Girardeau, MO to Affton, MO

Plan the drive back the other way.

107.8 mi 2h 4m

Continue From Cape Girardeau, MO

Troy, MO 157.1 mi · 3h 4m Bridgeton, MO 125.2 mi · 2h 27m St. Louis, MO 115.2 mi · 2h 12m Clayton, MO 115.1 mi · 2h 17m

More from Affton, MO

Columbia, MO 123.7 mi · 2h 33m Saint Peters, MO 31.5 mi · 35m

More trips to Cape Girardeau, MO

Smithville, MO 373.7 mi Excelsior Springs, MO 346.3 mi Neosho, MO 343.5 mi Richmond, MO 330.6 mi Marshfield, MO 252.5 mi Troy, MO 156.8 mi

Explore more options from Affton, MO or browse trips ending in Cape Girardeau, MO.

Looking for more statewide routes? Browse MO road trips.

Explore maps for Affton, MO or Cape Girardeau, MO on MapSof.net.