Last recalculated Apr 15, 2026
Drive Time
5h 10m
Distance
263.4 mi
424 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$40
one way
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Biloxi, MS
Wikimedia Commons
New Hope, MS
James Mirakian
Embarking on a journey from Biloxi, Mississippi, to New Hope, Mississippi, covers a distance of 263.4 miles and is estimated to take approximately 5 hours and 10 minutes of driving time. This highway-focused drive, primarily utilizing Lance Corporal Roy M Wheat Memorial Highway and US 45, is well-suited for a single day trip. With an estimated fuel cost of around $40, it's an economical option for exploring the Southeast region. You'll find this route offers a straightforward path with minimal complexity, making it a practical choice for getting from point A to point B efficiently.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
131.7 miles from Biloxi, MS
A natural place for your longest stop of the day , about 2h 33m into the drive .
This route is predominantly a highway-focused drive, with 61% of the journey on main roads like Lance Corporal Roy M Wheat Memorial Highway and US 45. Expect stretches of consistent speed on these main arteries, including one segment of 88.4 miles on Lance Corporal Roy M Wheat Memorial Highway without significant interruptions. While not characterized by winding country lanes, the transitions between these highways offer a sense of progression through the Mississippi landscape. The overall driving experience is one of steady progress rather than highly varied terrain.
This is a straightforward highway drive that stays mostly on Lance Corporal Roy M Wheat Memorial Highway and US 45. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 25.1 miles in.
High effort - long or complex enough to need steady focus all day
This is a demanding drive. With 20 significant decision points across 263.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 70.4 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 159.6 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
These are the spots where you need to pay the most attention. Preview them before you drive.
Keep slight right at fork toward US 49 North: Hattiesburg, Jackson
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Take the exit onto US 98 toward I 59 North, US 98 West: Columbia, Laurel
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight right at fork onto I 59 toward I 59 North, I 20 East: Meridian, Tuscaloosa
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward US 45 North: Macon
Exit ramp - move to the correct lane early. Lane positioning matters here
Keep slight right at fork onto US 45 toward US 45 North: Columbus, Aberdeen
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Biloxi, MS and New Hope, MS, road signs point toward Jackson, Laurel, Tuscaloosa and Aberdeen.
Jackson
Laurel
Tuscaloosa
Aberdeen
| Road | Distance | Duration |
|---|---|---|
| Lance Corporal Roy M Wheat Memorial Highway | 88.4 mi | 1h 35m |
| US 45 | 82.8 mi | 1h 35m |
| US 49 | 42.2 mi | 49m |
| MS 15 | 20.7 mi | 24m |
| I 59 | 9 mi | 10m |
| Alabama Street | 4.3 mi | 7m |
| US 98 | 3.3 mi | 4m |
| I 110 | 3.1 mi | 4m |
Step-by-step road directions between Biloxi, MS and New Hope, MS.
Start on Howard Avenue
Turn right onto Main Street
Turn left onto Division Street
Take the ramp onto Bohn Street
Turn straight
Merge onto I 110
Continue on MS 15; MS 67
Keep slight right at fork
Merge onto US 49
Continue on US 49
Take the exit
Merge onto US 98
Take the exit onto US 98
Merge onto I 59; US 98
Keep slight right at fork onto I 59
Take the exit
Merge onto US 45
Keep slight right at fork onto US 45
Continue on US 45
Continue on Plymouth Bluff Access Road
Take the exit
Take the exit
Keep slight right at fork
Turn straight onto MS 69
Enter roundabout onto MS 69; MS 182
Continue on MS 69; MS 182
Continue on MS 69; MS 182
Turn right onto New Hope Road
Arrive at destination
For this 5-hour, 10-minute drive, departing in the morning will give you ample time to reach New Hope without feeling rushed, and it allows for a single planned stop. Given the 263.4-mile distance, consider a brief break around the halfway point to stretch your legs and refuel if necessary, keeping the $40 fuel budget in mind. Pay attention to highway signage as you navigate between Lance Corporal Roy M Wheat Memorial Highway and US 45 to ensure smooth transitions. This trip is manageable in one day, offering flexibility to adjust your schedule as needed.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 58 miles or 1h 11m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 131.7 miles or 2h 33m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 8m
Traffic, exits, and arrival timing usually matter more near New Hope, MS than in the middle of the route.
Open the route before leaving Biloxi, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Biloxi, MS
This is one driving day of about 263.4 miles and 5h 10m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 131.7 mi from Biloxi, MS · 2h 33m into the drive
Mid-route town
Meal stop
132 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 58 miles helps settle the day before fatigue starts building.
The midpoint is around 131.7 miles from Biloxi, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Lance Corporal Roy M Wheat Memorial Highway if your tank is already low. That segment runs about 88.4 miles.
The final approach into New Hope, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around New Hope, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$39.78 one way
$79.56 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.21 | $43.67 | $87.34 |
| premium | $4.56 | $47.28 | $94.55 |
| diesel | $5.61 | $58.16 | $116.31 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$40
Meals
$25–$50
Total
$65–$90
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 92.2 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $28 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 79 | 0 | $27.66 | $12.64 |
| Efficient EV | 65.9 | 0 | $23.05 | $10.54 |
| EV Truck/SUV | 105.4 | 1 | $36.88 | $16.86 |
Gas CO2
92 kg
EV CO2
31 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Biloxi on Wednesday
Local time
3:50 PM
CDT
Current temp
77°F
Sunny
Destination
Afternoon in New Hope on Wednesday
Local time
3:50 PM
CDT
Current temp
64°F
Unavailable
79°F
Newton, MS
132 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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