Origin
Blair, WI
Late night in Blair on Saturday
Local time
12:00 AM
CDT
Current temp
69°F
Unavailable
Live forecast
Trip from Blair, WI to La Crosse, WI
Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
1h 3m
Distance
42.7 mi
69 km
Drive Score
6/10
Good drive
Same Day?
Yes, doable
Fuel Cost
$7
one way
EV Charging
Unknown
Best Time to Leave
4 AM
0h 59m
★
6 AM
1h 4m
8 AM
1h 14m
10 AM
1h 7m
12 PM
1h 6m
3 PM
1h 8m
5 PM
1h 13m
8 PM
1h 1m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Blair, WI
Wikimedia Commons
La Crosse, WI
Wikimedia Commons
Trip Overview
The drive from Blair, WI to La Crosse, WI covers 42.7 miles and takes about 1h 3m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 53, WI 16, 16th Street South for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 35.5 miles on US 53. At current regular gas prices, budget about $6.68 one way before food or hotel costs.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 1h 3m. Total distance: 42.7 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 3m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (93%). Straightforward navigation.
Drive Character
This is a 1h 3m highway drive covering 42.7 miles, with most of the trip on US 53 and WI 16. The longest continuous stretch is about 35.5 miles on US 53.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 15 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 53 is the longest continuous segment at about 35.5 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on US 53 and WI 16. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near WI 95 / State Highway 95.
Driving Effort
4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 3m drive. You will face about 8 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start (WI 95 / State Highway 95): Navigation decision point; at 0.3 miles (WI 95 / West 4th Street): Navigation decision point; at 0.7 miles (US 53): Navigation decision point.
Critical Maneuvers
5 of 8 key pointsThese are the spots where you need to pay the most attention. Preview them before you drive.
4
0 mi into trip
|
~0m in
|
WI 95 / State Highway 95
Turn left onto WI 95 / State Highway 95
Navigation decision point
5
0.3 mi into trip
|
~0m in
|
WI 95 / West 4th Street
At end of road, turn right onto WI 95 / West 4th Street
Navigation decision point
4
0.7 mi into trip
|
~1m in
|
US 53
At end of road, turn left onto US 53
Navigation decision point
4
40.8 mi into trip
|
~58m in
|
CTH F / Main Street
Turn right onto CTH F / Main Street
Navigation decision point
5
42.6 mi into trip
|
~1h 3m in
|
WI 35 / West Avenue South
At end of road, turn right onto WI 35 / West Avenue South
Navigation decision point
Main Roads
| Road | Distance | Duration |
|---|---|---|
| US 53 | 35.5 mi | 48m |
| WI 16 | 3.4 mi | 5m |
| 16th Street South | 0.8 mi | 2m |
| Main Street | 0.7 mi | 1m |
| WI 157 | 0.6 mi | 1m |
| Losey Boulevard North | 0.5 mi | 1m |
| State Highway 95 | 0.3 mi | <1m |
| Johnson Street | 0.3 mi | 1m |
Longest stretch:
US 53
— 35.5 mi, about 48m
Turn-by-Turn Driving Directions
Step-by-step road directions between Blair, WI and La Crosse, WI.
1
Start on CTH S
97 ft
·
7 sec
·
West Broadway Street
2
Turn left onto WI 95
0.3 mi
·
24 sec
·
State Highway 95
3
At end of road, turn right onto WI 95
0.3 mi
·
26 sec
·
West 4th Street
4
Continue on WI 95
495 ft
·
13 sec
·
State Highway 95
5
At end of road, turn left onto US 53
18 mi
·
26 min
·
US 53
6
Turn left onto US 53; WI 93; WI 54
18 mi
·
22 min
·
US 53; WI 93; WI 54
7
Turn straight onto WI 157
0.6 mi
·
1 min
·
WI 157
8
Turn slight right
0.1 mi
·
18 sec
9
Turn straight onto WI 16
3.4 mi
·
5 min
·
WI 16
10
Continue on Losey Boulevard North
0.5 mi
·
1 min
·
Losey Boulevard North
11
Turn right onto CTH F
0.7 mi
·
1 min
·
Main Street
12
Turn left onto 16th Street South
0.8 mi
·
2 min
·
16th Street South
13
Turn right onto Johnson Street
0.3 mi
·
1 min
·
Johnson Street
14
At end of road, turn right onto WI 35
326 ft
·
11 sec
·
West Avenue South
15
Arrive at destination
WI 35
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 21.4 mi from Blair, WI · 30m into the drive
Mid-route town
Meal stop
21 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 42.7 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 21.4 miles from Blair, WI, which is a good place for a longer meal and fuel stop.
Arriving in La Crosse, WI
The final approach into La Crosse, WI usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$6.68 one way
$13.35 round trip
$3.97/gal
25.4 MPG avg
15 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $7.33 | $14.66 |
| premium | $4.89 | $8.22 | $16.43 |
| diesel | $5.61 | $9.43 | $18.86 |
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$7
Estimated CO2 emission: 14.9 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $4 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 12.8 | 0 | $4.48 | $2.05 |
| Efficient EV | 10.7 | 0 | $3.74 | $1.71 |
| EV Truck/SUV | 17.1 | 0 | $5.98 | $2.73 |
Gas CO2
15 kg
EV CO2
5 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
La Crosse, WI
Late night in La Crosse on Saturday
Local time
12:00 AM
CDT
Current temp
77°F
Partly Sunny then Showers And Thunderstorms
S 8 to 16 mph
90% chance
Live forecast
67°F
Ettrick, WI
21 mi in
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
8 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 3m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Blair, WI to La Crosse, WI covers 42.7 miles and takes about 1h 3m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 53, WI 16, 16th Street South. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 21.4 miles from Blair, WI. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $6.68 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a straightforward 1h 3m drive. You will face about 8 decision points, but nothing that requires special attention if you follow navigation.
The main spots that need attention: near the start (WI 95 / State Highway 95): Navigation decision point; at 0.3 miles (WI 95 / West 4th Street): Navigation decision point; at 0.7 miles (US 53): Navigation decision point.
The route from Blair, WI to La Crosse, WI does not surface many named destination signs beyond the main corridor.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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