The drive from Brandon, MS to Greenwood, MS covers 200.8 miles and takes about 4h 11m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on MS 25, MS 471, US Highway 45 Alternate for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 76.3 miles on MS 25.
At current regular gas prices, budget about $30.33 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
100.4 miles from Brandon, MS
A natural place for your longest stop of the day
, about 1h 59m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h 11m. Total distance: 200.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 11m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (88%). Some complex stretches to watch for.
Drive Character
This is a 4h 11m highway drive covering 200.8 miles, with most of the trip on MS 25 and MS 471. The longest continuous stretch is about 76.3 miles on MS 25.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 21 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
MS 25 is the longest continuous segment at about 76.3 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on MS 25 and MS 471. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.5 miles in near MS 471 / Hwy 471.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 12 significant decision points across 200.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.5 miles (MS 471 / Hwy 471): Lane positioning matters here; at 112.7 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here; at 118.9 miles (MS 25): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 12 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
0.5 mi into trip|~0m in|MS 471 / Hwy 471
Turn right onto MS 471 / Hwy 471
Lane positioning matters here
Use the right lane.
6
112.7 mi into trip|~2h 14m in|MS 25
Keep slight right at fork onto MS 25
Highway fork - watch signs carefully. Lane positioning matters here
Use the left lane.
6
118.9 mi into trip|~2h 21m in|MS 25
Keep slight right at fork onto MS 25 toward US 82 East, MS 25 North: Columbus, West Point
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 82 East, MS 25 North: Columbus, West...
5
131.3 mi into trip|~2h 35m in
Take the exit toward US 45 Alternate North, MS 25 North: West Point, Tupelo
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 45 Alternate North, MS 25 North: West...
5
131.5 mi into trip|~2h 35m in|US 45 ALT; MS 25 / US Highway 45 Alternate
Merge onto US 45 ALT; MS 25 / US Highway 45 Alternate
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Brandon, MS and Greenwood, MS, road signs point toward Point and Tupelo.
Point
118.9 mi in|~2h 21m|via MS 25
Tupelo
131.3 mi in|~2h 35m
Main Roads
Road
Distance
Duration
MS 25
76.3 mi
1h 27m
MS 471
46.8 mi
53m
US Highway 45 Alternate
34.6 mi
42m
Martin Luther King Drive
18.1 mi
20m
MS 178
7.5 mi
10m
Highway 471
6.2 mi
10m
MS 6
4.6 mi
7m
Dorsey Evergreen Road
2.9 mi
11m
Longest stretch:
MS 25
— 76.3 mi, about 1h 27m
Turn-by-Turn Driving Directions
Step-by-step road directions between Brandon, MS and Greenwood, MS.
1
Start on US 80
0.5 mi·46 sec·East Government Street
2
Turn right onto MS 471
1.5 mi·2 min·Hwy 471
Use the right lane.
3
Continue on MS 471
6.2 mi·10 min·Highway 471
4
Take the ramp onto MS 471
47 mi·53 min·MS 471
5
Continue on MS 25
33 mi·37 min·MS 25
6
Take the exit onto MS 25
25 mi·29 min·MS 25
7
Keep slight right at fork onto MS 25
2.4 mi·2 min·MS 25
Use the left lane.
8
Continue on MS 25
3.8 mi·4 min·MS 25
9
Keep slight right at fork onto MS 25
12 mi·13 min·MS 25
Toward US 82 East, MS 25 North: Columbus, West Point
10
Take the exit
0.3 mi·34 sec
Toward US 45 Alternate North, MS 25 North: West Point, Tupelo
11
Merge onto US 45 ALT; MS 25
35 mi·42 min·US Highway 45 Alternate
Use the straight lane.
12
Continue on US 45 ALT
18 mi·20 min·Martin Luther King Drive
13
Continue on US 45; MS 6
1.5 mi·2 min·Martin Luther King, Junior Drive
14
Take the exit onto MS 6
0.4 mi·49 sec·MS 6
Toward MS 6 East: Downtown Tupelo
15
Keep slight right at fork onto MS 6
4.2 mi·6 min·MS 6
16
Continue on MS 178
7.5 mi·10 min·MS 178
17
Turn right onto Dorsey Evergreen Road
0.4 mi·1 min·Dorsey Evergreen Road
18
Turn right onto Bankhead Road Southwest
0.1 mi·27 sec·Bankhead Road Southwest
19
Turn left onto Dorsey Evergreen Road
2.5 mi·9 min·Dorsey Evergreen Road
20
Turn right onto Greenwood Hopewell Road
145 ft·6 sec·Greenwood Hopewell Road
21
Arrive at destination
Greenwood Hopewell Road
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 100.4 miles from Brandon, MS, or about 1h 59m into the drive.
The longest continuous stretch on this route runs about 76.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 44 miles or 55m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 100.4 miles or 1h 59m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 16m
Traffic, exits, and arrival timing usually matter more near Greenwood, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Brandon, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Brandon, MS
This is one driving day of about 200.8 miles and 4h 11m.
Your first comfortable stop window is around 44 miles from Brandon, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS 25 for about 76.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 100.4 mi from Brandon, MS
· 1h 59m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Tupelo National Battlefield
National Battlefield
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
3 mi from route
~8 min detour
Free
near mile 186.9
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
5 mi from route
~13 min detour
Free
near mile 186.9
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$30.33 one way
$60.65 round trip
$3.84/gal25.4 MPG avg70 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$33.29
$66.58
premium
$4.56
$36.04
$72.08
diesel
$5.61
$44.33
$88.67
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 70.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $21 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
60.2
0
$21.08
$9.64
Efficient EV
50.2
0
$17.57
$8.03
EV Truck/SUV
80.3
1
$28.11
$12.85
Gas CO2
70 kg
EV CO2
23 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Brandon, MS
Late night
in Brandon on Friday
Local time
2:55 AM
CDT
Current temp
56°F
Unavailable
Live forecast
Destination
Greenwood, MS
Late night
in Greenwood on Friday
Local time
2:55 AM
CDT
Current temp
77°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
21 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 11m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Brandon, MS to Greenwood, MS covers 200.8 miles and takes about 4h 11m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are MS 25, MS 471, US Highway 45 Alternate. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 100.4 miles from Brandon, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $30.33 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 12 significant decision points across 200.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.5 miles (MS 471 / Hwy 471): Lane positioning matters here; at 112.7 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here; at 118.9 miles (MS 25): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Between Brandon, MS and Greenwood, MS, road signs point toward Point and Tupelo.
Yes. Nearby national parks include Tupelo National Battlefield, Natchez Trace National Scenic Trail and Medgar and Myrlie Evers Home National Monument.
How this page is built
Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from
OSRM
over
OpenStreetMap.
Fuel cost uses
EIA
weekly regional averages.
National park proximity is from the
NPS API.
Pages are published only after passing our data-quality checks; our
methodology page
documents refresh cadence, editorial standards, and known limitations.
