Trip from Brandon, MS to Biloxi, MS

Last recalculated Apr 16, 2026

Drive Time

3h 25m

Distance

161.7 mi

260 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$24

one way

Best Time to Leave

Save up to 36 min

4 AM

3h 14m ★

6 AM

3h 26m

8 AM

3h 50m

10 AM

3h 34m

12 PM

3h 32m

3 PM

3h 35m

5 PM

3h 49m

8 PM

3h 18m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly

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Brandon, MS

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Biloxi, MS

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Trip Overview

This 161.7-mile drive from Brandon, MS, to Biloxi, MS, is a straightforward, highway-focused journey that can easily be completed in about 3 hours and 25 minutes. Given its manageable distance and duration, it's perfectly suited for a single-day road trip, with an estimated fuel cost of around $24. The route primarily utilizes US 49, with portions of the Biloxi-D'Iberville Scenic Expressway and Highway 18 also incorporated. You'll be spending about 91% of your time on highways, making for a relatively efficient trip through the Southeast region of Mississippi.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

80.9 miles from Brandon, MS

A natural place for your longest stop of the day , about 1h 46m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 3h 25m. Total distance: 161.7 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

3h 25m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (91%). Some complex stretches to watch for.

Drive Character

Expect a predominantly highway experience on this route, with 91% of the drive taking place on faster roads. The longest uninterrupted stretch you'll encounter is 95.9 miles on US 49, offering a good period of consistent travel. While the profile is highway-focused, the inclusion of roads like the Biloxi-D'Iberville Scenic Expressway suggests potential for slightly varied scenery or a change in road type as you near your destination. Overall, this drive is designed for getting you from point A to point B with efficiency, rather than focusing on a winding, scenic byway experience.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.

There are about 22 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

US 49 is the longest continuous segment at about 95.9 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on US 49 and Biloxi-D'Iberville Scenic Expressway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 82.2 miles in.

Route Complexity 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

This is a demanding drive. With 15 significant decision points across 161.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 82.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 82.6 miles (I 59 / Lance Corporal Roy M Wheat Memorial Highway): Merge point - match speed before joining. Lane positioning matters here; at 90.3 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Critical Maneuvers

5 of 15 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

82.2 mi into trip | ~1h 48m in

Take the exit toward I 59 South: New Orleans, Gulf Coast

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Toward I 59 South: New Orleans, Gulf Coast

82.6 mi into trip | ~1h 49m in | I 59 / Lance Corporal Roy M Wheat Memorial Highway

Merge onto I 59 / Lance Corporal Roy M Wheat Memorial Highway toward Mississippi Gulf Coast

Merge point - match speed before joining. Lane positioning matters here

Use the straight lane. Toward Mississippi Gulf Coast

90.3 mi into trip | ~1h 57m in | US 98

Take the exit onto US 98 toward US 98 East: Lucedale, Mobile

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 98 East: Lucedale, Mobile

93.5 mi into trip | ~2h 1m in

Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 49: Wiggins, Gulfport, Mississippi Gu...

93.8 mi into trip | ~2h 2m in

Keep slight left at fork toward Multi Purpose Center, Hattiesburg

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left / slight right lanes. Toward Multi Purpose Center, Hattiesburg

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Brandon, MS and Biloxi, MS, road signs point toward Gulf Coast, Mississippi Gulf Coast, Mobile, Gulfport, Multi Purpose Center and Hattiesburg.

Gulf Coast

82.2 mi in | ~1h 48m

Mississippi Gulf Coast

82.6 mi in | ~1h 49m | via I 59

Mobile

90.3 mi in | ~1h 57m | via US 98

Gulfport

93.5 mi in | ~2h 1m

Multi Purpose Center

93.8 mi in | ~2h 2m

Hattiesburg

93.8 mi in | ~2h 2m

Main Roads

Road	Distance	Duration
US 49	95.9 mi	1h 54m
Biloxi-D'Iberville Scenic Expressway	20.5 mi	24m
Highway 18	16 mi	23m
Highway 13 North	9.2 mi	13m
Lance Corporal Roy M Wheat Memorial Highway	7.7 mi	8m
US 98	3.2 mi	4m
I 110	3.2 mi	4m
Louis Wilson Drive	2.6 mi	4m

Longest stretch: US 49 — 95.9 mi, about 1h 54m

Turn-by-Turn Driving Directions

Step-by-step road directions between Brandon, MS and Biloxi, MS.

Start on US 80

0.3 mi · 27 sec · East Government Street

Turn right onto Louis Wilson Drive

2.6 mi · 4 min · Louis Wilson Drive

Use the right lane.

At end of road, turn left onto MS 18

16 mi · 23 min · Highway 18

Turn right onto MS 13

9.2 mi · 13 min · Highway 13 North

Take the ramp

0.2 mi · 22 sec

Merge onto US 49

53 mi · 1 hr 3 min · US 49

Use the straight lane.

Continue on US 49; MS 42

0.4 mi · 35 sec · US 49; MS 42

Use the straight lane.

Continue on US 49; MS 42

1.1 mi · 1 min · US 49; MS 42

Use the straight lane.

Take the exit

0.4 mi · 36 sec

Toward I 59 South: New Orleans, Gulf Coast Use the slight right lane.

Merge onto I 59

7.7 mi · 8 min · Lance Corporal Roy M Wheat Memorial Highway

Toward Mississippi Gulf Coast Use the straight lane.

Take the exit onto US 98

3.2 mi · 4 min · US 98

Toward US 98 East: Lucedale, Mobile Use the straight / slight right lanes.

Take the exit

0.3 mi · 44 sec

Toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast Use the straight / slight right lanes.

Keep slight left at fork

0.2 mi · 27 sec

Toward Multi Purpose Center, Hattiesburg Use the slight left / slight right lanes.

Turn right onto US 49

42 mi · 49 min · US 49

Use the straight lane.

Take the exit

0.8 mi · 1 min

Toward MS 67 South: D'Iberville, Biloxi

Continue on MS 67

20 mi · 24 min · Biloxi-D'Iberville Scenic Expressway

Continue on I 110

3.2 mi · 4 min · I 110

Take the exit

0.4 mi · 47 sec

Exit 1c Toward Division Street

Turn left onto Division Street

0.6 mi · 1 min · Division Street

Turn right onto Main Street

0.5 mi · 1 min · Main Street

Turn left onto Howard Avenue

91 ft · 3 sec · Howard Avenue

Arrive at destination

Howard Avenue

Trip Plan

This 3-hour and 25-minute drive is ideal for a single-day excursion, so you have flexibility with your departure time. Consider leaving in the morning to maximize your day in Biloxi. With only one recommended stop factored in, you can decide if you need a break during the 95.9-mile stretch on US 49. Keep an eye on your fuel gauge, as the estimated cost is $24, and plan your refueling accordingly, especially before embarking on longer highway segments. The highway-focused nature means you can cover ground quickly, making it easy to adjust your schedule on the fly.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 80.9 miles from Brandon, MS, or about 1h 46m into the drive.

The longest continuous stretch on this route runs about 95.9 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 36 miles or 52m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 80.9 miles or 1h 46m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 48m

Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.

Before You Leave

Open the route before leaving Brandon, MS so your first major turns are already loaded.

Leave with enough water and a charging cable within reach, not packed away.

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Brandon, MS

This is one driving day of about 161.7 miles and 3h 25m.

Your first comfortable stop window is around 36 miles from Brandon, MS.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

The longest stretch is on US 49 for about 95.9 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 80.9 mi from Brandon, MS · 1h 46m into the drive

Mid-route town

Meal stop

Hattiesburg, MS

81 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Magee, MS

Fuel and coffee

A short stop after about 36 miles helps settle the day before fatigue starts building.

Hattiesburg, MS

Meal break

The midpoint is around 80.9 miles from Brandon, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before US 49 if your tank is already low. That segment runs about 95.9 miles.

Arriving in Biloxi, MS

The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$24.42 one way

$48.84 round trip

$3.84/gal 25.4 MPG avg 57 kg CO₂

Fuel Type	$/gal	One Way	Round Trip
midgrade	$4.21	$26.81	$53.62
premium	$4.56	$29.02	$58.05
diesel	$5.61	$35.70	$71.40

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$24

Meals

$25–$50

Total

$49–$74

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 56.6 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $17 in charging · 0 stops · 67% less CO₂

Vehicle Type	kWh	DC Fast	Home Charge
Average EV	48.5	$16.98	$7.76
Efficient EV	40.4	$14.15	$6.47
EV Truck/SUV	64.7	$22.64	$10.35

Gas CO2

57 kg

EV CO2

19 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Brandon, MS

Late night in Brandon on Thursday

Local time

3:48 AM

CDT

Current temp

56°F

Unavailable

Live forecast

Destination

Biloxi, MS

Late night in Biloxi on Thursday

Local time

3:48 AM

CDT

Current temp

61°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

5 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

3h 25m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Brandon, MS to Biloxi, MS covers 161.7 miles and takes about 3h 25m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are US 49, Biloxi-D'Iberville Scenic Expressway, Highway 18. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 80.9 miles from Brandon, MS. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $24.42 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.

Between Brandon, MS and Biloxi, MS, road signs point toward Gulf Coast, Mississippi Gulf Coast, Mobile, Gulfport, Multi Purpose Center and Hattiesburg.

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Trip from Brandon, MS to Biloxi, MS

Best Time to Leave

Trip Overview

Who Is This Route For?

Drive Character

How Hard Is This Drive?

Critical Maneuvers

Towns Mentioned on Route Signs

Main Roads

Turn-by-Turn Driving Directions

Trip Plan

Before You Leave

Where to Stop

Pacing Suggestions

Arriving in Biloxi, MS

Fuel & Cost

Travel Intel

Brandon, MS

Biloxi, MS

Same local time

5 degrees warmer at arrival

3h 25m on the road

Frequently Asked Questions

Explore More

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