De Soto National Memorial
National Memorial
In May 1539, Conquistador Hernando de Soto’s army of soldiers, hired mercenaries, craftsmen, and clergy made landfall in Tampa Bay. They were met with fierce resistance of indigenous people protecting...
Last recalculated Apr 17, 2026
Drive Time
6h 10m
Distance
302.7 mi
487 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$48
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Cape Coral, FL
Wikimedia Commons
Fleming Island, FL
Arian Fernandez
The drive from Cape Coral, FL to Fleming Island, FL covers 302.7 miles and takes about 6h 10m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 75, FL 21, US 301 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 198.8 miles on I 75. At current regular gas prices, budget about $48.18 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
151.4 miles from Cape Coral, FL
A natural place for your longest stop of the day , about 2h 56m into the drive .
Weekend Trip
Doable as a same-day drive at 6h 10m. Total distance: 302.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 10m drive, plan rest stops for pacing.
First-Time Driver
Mostly highway driving (86%). Straightforward navigation.
This is a 6h 10m highway drive covering 302.7 miles, with most of the trip on I 75 and FL 21. The longest continuous stretch is about 198.8 miles on I 75.
This is a straightforward highway drive that stays mostly on I 75 and FL 21. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near Vincennes Boulevard.
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
The route itself is not hard, but at 6h 10m, endurance matters. Plan breaks every 2-3 hours. The 16 decision points are all manageable with basic attention.
Where does it get tricky?
The main spots that need attention: near the start (Vincennes Boulevard): Lane positioning matters here; at 0.1 miles (Vincennes Boulevard): Roundabout - know your exit number before entering; at 24.9 miles (I 75): Merge point - match speed before joining. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn right onto Vincennes Boulevard
Lane positioning matters here
Enter roundabout onto Vincennes Boulevard
Roundabout - know your exit number before entering
Merge onto I 75
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward FL 326
Exit ramp - move to the correct lane early. Lane positioning matters here
Turn left onto FL 21
Lane positioning matters here
| Road | Distance | Duration |
|---|---|---|
| I 75 | 198.8 mi | 3h 33m |
| FL 21 | 31.8 mi | 46m |
| US 301 | 26 mi | 32m |
| North Tamiami Trail | 10.4 mi | 12m |
| Doctors Inlet Road | 8.1 mi | 14m |
| County Road 219A | 6.5 mi | 8m |
| Del Prado Boulevard North | 6.5 mi | 10m |
| Del Prado Boulevard South | 5.2 mi | 10m |
Step-by-step road directions between Cape Coral, FL and Fleming Island, FL.
Start on this road
Turn right onto Cape Coral Parkway East
Turn right onto Vincennes Boulevard
Enter roundabout onto Vincennes Boulevard
Continue on Vincennes Boulevard
Turn right onto Coronado Parkway
Turn left onto CR 867A
Continue on CR 867A
Turn left onto US 41
Turn right onto CR 762
Take the ramp
Merge onto I 75
Take the exit
Turn slight right
Turn slight right onto FL 326
Continue on FL 326
Turn left onto US 301; US 441
Turn straight onto US 301
Turn straight onto CR 219A
At end of road, turn right onto FL 26
Turn left onto FL 21
Turn slight right onto Doctors Inlet Road
Continue on CR 220
Turn right onto East West Parkway
Turn right onto Town Center Boulevard
Enter roundabout
Continue
Continue on Radar Road
Turn right
Arrive at destination
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 67 miles or 1h 25m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 151.4 miles or 2h 56m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 46m
Traffic, exits, and arrival timing usually matter more near Fleming Island, FL than in the middle of the route.
Open the route before leaving Cape Coral, FL so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Cape Coral, FL
This is one driving day of about 302.7 miles and 6h 10m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 151.4 mi from Cape Coral, FL · 2h 56m into the drive
Mid-route town
Meal stop
151 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 67 miles helps settle the day before fatigue starts building.
The midpoint is around 151.4 miles from Cape Coral, FL, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 75 if your tank is already low. That segment runs about 198.8 miles.
The final approach into Fleming Island, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Fleming Island, FL.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Worth a detour if your schedule allows.
National Memorial
In May 1539, Conquistador Hernando de Soto’s army of soldiers, hired mercenaries, craftsmen, and clergy made landfall in Tampa Bay. They were met with fierce resistance of indigenous people protecting...
National Monument
Built by the Spanish in St. Augustine to defend Florida and the Atlantic trade route, Castillo de San Marcos National Monument preserves the oldest masonry fortification in the continental United Stat...
Park data from the National Park Service API. Alerts update every 2 hours.
Regular Gas
$48.18 one way
$96.36 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.40 | $52.41 | $104.82 |
| premium | $4.72 | $56.29 | $112.57 |
| diesel | $5.61 | $66.83 | $133.66 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$48
Meals
$25–$50
Total
$73–$98
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 105.9 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $32 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 90.8 | 1 | $31.78 | $14.53 |
| Efficient EV | 75.7 | 0 | $26.49 | $12.11 |
| EV Truck/SUV | 121.1 | 1 | $42.38 | $19.37 |
Gas CO2
106 kg
EV CO2
35 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Evening in Cape Coral on Thursday
Local time
8:59 PM
EDT
Current temp
66°F
Unavailable
Destination
Evening in Fleming Island on Thursday
Local time
8:59 PM
EDT
Current temp
80°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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