Origin
Caruthersville, MO
Afternoon in Caruthersville on Sunday
Local time
2:36 PM
CDT
Current temp
80°F
Unavailable
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Create accountDrive Time
6h 45m
Distance
326.8 mi
526 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$50
one way
Caruthersville, MO
Renegade Lenz
Joplin, MO
Miloš Steklý
Crossing Missouri from Caruthersville to Joplin covers a total distance of 326.8 miles, typically requiring about 6 hours and 45 minutes of travel time. Because this is a highway-focused drive, you can comfortably complete the journey in a single day, though it will be a full day on the road. Budgeting roughly $50 for fuel should cover your primary transit costs along the route. Navigating mainly via US 60, the Captain Aaron J. Eidem Memorial Highway, and MO 53, you will traverse the heart of the Midwest. Whether you are looking for a straightforward transit or a long-haul trek, this route offers a reliable connection between these two Missouri cities without the need for an overnight split.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
163.4 miles from Caruthersville, MO
A natural place for your longest stop of the day , about 3h 30m into the drive .
Expect a trip defined by its highway-focused nature, with 78% of your travel occurring on major thoroughfares. The personality of this drive is anchored by a significant 190.3-mile stretch on US 60, which serves as the backbone of your journey. You will spend most of your time maintaining a steady pace, as the route is designed for efficiency rather than technical, winding roads. As you shift between the Captain Aaron J. Eidem Memorial Highway and the various state routes, the environment remains consistent with a standard Midwestern highway experience. It is a practical, no-nonsense drive that rewards drivers who appreciate the rhythm of long, uninterrupted miles.
This is a straightforward highway drive that stays mostly on US 60 and Captain Aaron J Eidem Memorial Highway. You will hit about 14 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near West 3rd Street.
Moderate - straightforward overall, but long enough or busy enough to require pacing
This drive requires moderate attention. Across 326.8 miles you will encounter 14 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (West 3rd Street): Navigation decision point; at 78.4 miles (US 60): Exit ramp - move to the correct lane early. Lane positioning matters here; at 264.7 miles: Highway fork - watch signs carefully.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn right onto West 3rd Street
Navigation decision point
Take the exit onto US 60
Exit ramp - move to the correct lane early. Lane positioning matters here
Keep slight left at fork toward I 44 West: Joplin
Highway fork - watch signs carefully
Take the exit onto I 44 Business; MO 66 toward I 44 Business, MO 66: Duenweg, Joplin
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Turn right
Navigation decision point
| Road | Distance | Duration |
|---|---|---|
| US 60 | 190.3 mi | 3h 43m |
| Captain Aaron J Eidem Memorial Highway | 52.7 mi | 56m |
| MO 53 | 34.6 mi | 51m |
| US 412 | 13.3 mi | 15m |
| Independence Street | 11.6 mi | 17m |
| I 44 Business | 8.5 mi | 17m |
| I 155 | 7.1 mi | 7m |
| South Westwood Boulevard | 2.4 mi | 3m |
Step-by-step road directions between Caruthersville, MO and Joplin, MO.
Start on this road
Turn right onto West 3rd Street
Turn right onto Ward Avenue
Turn right onto MO 84
Turn straight onto MO U
Take the ramp
Merge onto I 155; US 412
Continue on US 412; MO 84
Take the exit
Turn straight onto MO 25
Turn left onto MO 53
Turn right onto US 67 Business
Continue on US 60 Business; US 67 Business
Continue on US 60 Business; US 67 Business
Continue on US 67; US 60 Business
Continue on US 60; US 67
Take the exit onto US 60
Keep slight left at fork
Merge onto I 44
Take the exit onto I 44 Business; MO 66
Turn right onto US Historic 66; MO 43
Turn right
Turn right
Arrive at destination
To keep your 6-hour and 45-minute drive manageable, plan for at least one dedicated stop to stretch your legs and refresh. Since the longest stretch spans 190.3 miles, try to time your break near the midpoint to avoid fatigue during the second half of the trip. Departing early in the morning is your best strategy to ensure you arrive in Joplin before the end of the day, leaving you with plenty of flexibility for the evening. Keep an eye on your fuel gauge throughout that long US 60 segment, as finding service stations can be less frequent depending on your specific pace. Use your $50 fuel budget as a baseline, but consider keeping a small buffer for local fluctuations as you move across the state.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 52m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 163.4 miles or 3h 30m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 34m
Traffic, exits, and arrival timing usually matter more near Joplin, MO than in the middle of the route.
Open the route before leaving Caruthersville, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Caruthersville, MO
This is one driving day of about 326.8 miles and 6h 45m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 163.4 mi from Caruthersville, MO · 3h 30m into the drive
Mid-route town
Meal stop
163 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 163.4 miles from Caruthersville, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US 60 if your tank is already low. That segment runs about 190.3 miles.
The final approach into Joplin, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Joplin, MO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$49.64 one way
$99.28 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $54.72 | $109.44 |
| premium | $4.80 | $61.69 | $123.39 |
| diesel | $5.64 | $72.60 | $145.21 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$50
Meals
$25–$50
Total
$75–$100
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 114.3 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $34 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 98 | 1 | $34.31 | $15.69 |
| Efficient EV | 81.7 | 0 | $28.60 | $13.07 |
| EV Truck/SUV | 130.7 | 1 | $45.75 | $20.92 |
Gas CO2
114 kg
EV CO2
38 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Caruthersville on Sunday
Local time
2:36 PM
CDT
Current temp
80°F
Unavailable
Destination
Afternoon in Joplin on Sunday
Local time
2:36 PM
CDT
Current temp
57°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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