Origin
Clayton, MO
Afternoon in Clayton on Sunday
Local time
2:36 PM
CDT
Current temp
81°F
Unavailable
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Create accountDrive Time
5h 17m
Distance
279.5 mi
450 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$42
one way
Clayton, MO
cottonbro studio
Joplin, MO
Miloš Steklý
Spanning 279.5 miles across the Missouri Midwest, this drive from Clayton to Joplin typically takes about 5 hours and 17 minutes to complete. Given the duration, it works perfectly as a single-day trip, allowing you to reach your destination without needing an overnight stay. You can expect to budget roughly $42 for fuel, making this an affordable cross-state trek. The route relies heavily on the Henry Shaw Ozark Corridor, I-44 Business, and the Police Officer Ernest M. Brockman Sr. Memorial Highway. Whether you are traveling for business or a change of scenery, this path provides a straightforward connection between the eastern and western sides of the state.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
139.7 miles from Clayton, MO
A natural place for your longest stop of the day , about 2h 37m into the drive .
Expect a turn-heavy local drive that demands your full attention behind the wheel. While about three-quarters of the journey utilizes major highways, the experience is defined by a massive 261.3-mile stretch along the Henry Shaw Ozark Corridor. This long, primary segment anchors the trip, though you should anticipate shifts in road character as you transition between the highway sections and local thoroughfares. The road doesn’t feel like a monotonous interstate grind; instead, the technical nature of the turns keeps the drive engaging from start to finish.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.6 miles in near South Hanley Road.
Easy - simple navigation with a manageable amount of wheel time
This is a straightforward 5h 17m drive. You will face about 8 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 0.6 miles (South Hanley Road): Lane positioning matters here; at 4.4 miles: Navigation decision point; at 4.5 miles (I 44 / Police Officer Robert Stanze Memorial Highway): Merge point - match speed before joining. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
At end of road, turn left onto South Hanley Road
Lane positioning matters here
Take the ramp toward I 44 West
Navigation decision point
Merge onto I 44 / Police Officer Robert Stanze Memorial Highway
Merge point - match speed before joining. Lane positioning matters here
Take the exit onto I 44 Business; MO 66 toward I 44 Business, MO 66: Duenweg, Joplin
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Turn right
Navigation decision point
| Road | Distance | Duration |
|---|---|---|
| Henry Shaw Ozark Corridor | 261.3 mi | 4h 43m |
| I 44 Business | 8.5 mi | 17m |
| Police Officer Ernest M. Brockman Sr. Memorial Highway | 3.5 mi | 4m |
| South Hanley Road | 2.6 mi | 5m |
| Police Officer Robert Stanze Memorial Highway | 1.5 mi | 1m |
| Laclede Station Road | 0.6 mi | 1m |
| Wydown Boulevard | 0.6 mi | 1m |
| Big Bend Boulevard | 0.4 mi | <1m |
Step-by-step road directions between Clayton, MO and Joplin, MO.
Start on Hillvale Drive
Turn left onto Wydown Boulevard
At end of road, turn left onto South Hanley Road
Continue on Laclede Station Road
Turn slight right onto Big Bend Boulevard
Turn left onto Murdoch Avenue
Take the ramp
Merge onto I 44
Continue on I 44
Continue on I 44; US 50
Take the exit onto I 44 Business; MO 66
Turn right onto US Historic 66; MO 43
Turn right
Turn right
Arrive at destination
Since the trip is manageable in one day, you have the flexibility to depart whenever suits your schedule best. Plan for at least one stop to break up the drive, as this will help you stay alert during the long segments. With the longest stretch covering 261.3 miles, be sure to check your fuel levels before hitting the main corridor to avoid unnecessary detours. Keep in mind that the turn-heavy profile of this route can be more fatiguing than a straight interstate shot, so pace yourself accordingly. If you find your energy dipping, use the I-44 Business sections to find a convenient place to pull over and stretch your legs.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 32m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 139.7 miles or 2h 37m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 14m
Traffic, exits, and arrival timing usually matter more near Joplin, MO than in the middle of the route.
Open the route before leaving Clayton, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Clayton, MO
This is one driving day of about 279.5 miles and 5h 17m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 139.7 mi from Clayton, MO · 2h 37m into the drive
Mid-route town
Meal stop
140 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 139.7 miles from Clayton, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Henry Shaw Ozark Corridor if your tank is already low. That segment runs about 261.3 miles.
The final approach into Joplin, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Joplin, MO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$42.45 one way
$84.91 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $46.80 | $93.60 |
| premium | $4.80 | $52.76 | $105.53 |
| diesel | $5.64 | $62.10 | $124.19 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$42
Meals
$25–$50
Total
$67–$92
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 97.8 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $29 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 83.9 | 1 | $29.35 | $13.42 |
| Efficient EV | 69.9 | 0 | $24.46 | $11.18 |
| EV Truck/SUV | 111.8 | 1 | $39.13 | $17.89 |
Gas CO2
98 kg
EV CO2
33 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Clayton on Sunday
Local time
2:36 PM
CDT
Current temp
81°F
Unavailable
Destination
Afternoon in Joplin on Sunday
Local time
2:36 PM
CDT
Current temp
57°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
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