Trip from Cincinnati, OH to Los Angeles, CA
Drive Time
31h 49m
Distance
2176.1 mi
Route Type
Long-distance drive
Multi-day driveTrip Overview
The drive from Cincinnati, OH to Los Angeles, CA covers 2176.1 miles and takes about 31h 49m behind the wheel. It usually feels better as a 4-day road trip than as one long push.
The route leans on Calhoun Street, Clifton Avenue, West Martin Luther King Junior Drive for much of the mileage, and the overall profile is long-distance drive. At current regular gas prices, budget about $317.42 one way before food or hotel costs.
Trip Pace
Best split across 4 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
9 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
1088.1 miles from Cincinnati, OH
A natural place for your longest stop of the day.
Drive Character
At 2176.1 miles and 31h 49m of driving, this is a route where fuel stops, weather, and timing matter more than any single turn. The main roads are Calhoun Street and Clifton Avenue.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| Calhoun Street | 0 mi | 0m |
| Clifton Avenue | 0 mi | 0m |
| West Martin Luther King Junior Drive | 0 mi | 0m |
| Hopple Street | 0 mi | 0m |
| I 75 North | 0 mi | 0m |
| I 74 West | 0 mi | 0m |
| Northwest Expressway | 0 mi | 0m |
| Circle Freeway | 0 mi | 0m |
Step-by-Step Directions
Start on Ohio Avenue
At the end of the road, turn left onto Calhoun Street
At the end of the road, turn right onto Clifton Avenue
Turn left onto West Martin Luther King Junior Drive
Turn straight onto Hopple Street
Take the ramp right toward I 75 North, I 74 West, US 27 North, US 52 West
Continue straight
Keep slight left to continue on I 74 West, US 52 West, US 27 North
Continue on Northwest Expressway
Merge slight right onto Circle Freeway
Keep slight left to continue on Northwest Expressway
Continue on Southeastern Avenue
Continue on Southeastern Avenue
Turn slight left onto East Raymond Street
Continue on Sam Jones Expressway
Take the exit slight right toward I 70 West
Merge slight left onto Dwight D Eisenhower Highway
Keep slight right to continue on I 70 West: Saint Louis
Keep slight left to continue on I 55 South, I 70 West: Saint Louis
Keep slight left to continue on I 55 South, I 64, IL 3, US 40 West: Louisville, Saint Louis
Merge slight left
Keep slight right to continue on IL 3 South: Cahokia
Keep slight right to continue on I 44 West, I 55 South, I 44 East: Tulsa, Memphis, Kansas City, Walnut Street
Keep slight right
Continue on Henry Shaw Ozark Corridor
Continue on George Washington Carver Memorial Highway
Continue on Will Rogers Turnpike
Keep slight right to continue on I 44 West, US 412 West, OK 66 West: Tulsa
Keep slight left to continue on Skelly Bypass
Keep slight left to continue on Skelly Bypass
Continue on Governor Roy Joseph Turner Turnpike
Continue on John Kilpatrick Turnpike
Take the exit slight right toward I 40 West: Yukon, Amarillo
Keep slight left to continue on I 40 West, US 270 West: Amarillo
Merge slight left onto Korean War Veterans Memorial Highway
Continue on Senator Ed Berrong Memorial Highway
Continue on Korean War Veterans Memorial Highway
Continue on Great Western Cattle Trail
Continue on Korean War Veterans Memorial Highway
Take the exit slight right toward Golden Shores, Oatman
Continue straight
Merge slight left onto Purple Heart Trail
Continue on Needles Freeway
Take the exit slight right toward J Street
Merge slight left onto Needles Freeway
Merge slight left onto Barstow and Mojave Freeway
Continue on CHP Officer Larry L. Wetterling and San Bernardino County Sheriff's Lieutenant Alfred E. Stewart Memorial Highway
Continue on Barstow and Mojave Freeway
Take the exit slight left
Take the exit slight right toward I 10 West: Los Angeles
Merge slight left onto San Bernardino Freeway
Take the exit slight left
Merge slight left onto I-10 Metro ExpressLanes
Merge slight right onto San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Merge slight left onto Santa Ana Freeway
Take the exit slight right toward Spring Street
Turn right onto North Spring Street
Turn left onto West 1st Street
Arrive at your destination
When to Leave
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
Consider an overnight stop or starting very early.
Drive Plan
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 220 miles
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 1088.1 miles
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 544 miles
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Last hour of driving
Traffic, exits, and arrival timing usually matter more near Los Angeles, CA than in the middle of the route.
Before You Leave
Open the route before leaving Cincinnati, OH so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Treat this as a 4-day road trip and book the overnight stop before the busiest arrival window.
Trip Strategy
Day 1
Settle into the route from Cincinnati, OH
Aim for roughly 544 miles and 8 hours of wheel time on this day.
Day 2
Keep the middle miles efficient
Aim for roughly 544 miles and 8 hours of wheel time on this day.
Day 3
Keep the middle miles efficient
Aim for roughly 544 miles and 8 hours of wheel time on this day.
Day 4
Finish the approach into Los Angeles, CA
Aim for roughly 544 miles and 8 hours of wheel time on this day.
Best Stop Towns on This Route
These towns line up with the pace of this drive and give you clearer places to stop with a purpose.
Late stop town
Coffee and fuel
544 mi into the route
Best for: Coffee, fuel, and an easy first stretch
This is a natural early stop once the first hours of the drive are behind you.
Late stop town
Overnight candidate
1088 mi into the route
Best for: Hotel check-in, dinner, and a fresh start
This lines up well with a realistic day-end stop if you are breaking the drive into stages.
Late stop town
Final reset
1632 mi into the route
Best for: Food, fuel, and one last short break
This is a smart final reset before the arrival run into Los Angeles, CA.
Suggested Overnight Stops
Night 1
544 mi · about 8h in
A practical overnight split lands near Cahokia, IL after about 544 miles or 8 hours of driving.
Night 2
1088 mi · about 15.9h in
A practical overnight split lands near Wichita Falls, TX after about 1088 miles or 15.9 hours of driving.
Night 3
1632 mi · about 23.9h in
A practical overnight split lands near Flagstaff, AZ after about 1632 miles or 23.9 hours of driving.
Travel Advice
Arrival Notes
Seasonal Notes
Stops Along the Way
Halfway Point
Midpoint
About 1088.1 mi from Cincinnati, OH
A short stop after about 220 miles helps settle the day before fatigue starts building.
The midpoint is around 1088.1 miles from Cincinnati, OH, which is a good place for a longer meal and fuel stop.
Overnight split
Hotel stopFor a steadier pace, wrap day one after about 544 miles or 8 hours on the road.
Final-third reset
Rest stopPlan one more short stretch-and-water break in the final third of the drive so the last arrival window feels easier.
These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| regular | $3.71 | $317.42 | $634.84 |
| midgrade | $4.24 | $363.43 | $726.85 |
| premium | $4.79 | $410.37 | $820.75 |
| diesel | $4.30 | $368.74 | $737.48 |
Based on 25.4 MPG average. Estimated CO2 emission: 761.4 kg one way.
Frequently Asked Questions
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