Trip from Los Angeles, CA to San Antonio, TX
Drive Time
19h 46m
Distance
1353.8 mi
Route Type
Long-distance drive
Multi-day driveTrip Overview
The drive from Los Angeles, CA to San Antonio, TX covers 1353.8 miles and takes about 19h 46m behind the wheel. It usually feels better as a 3-day road trip than as one long push.
The route leans on North Main Street, East Aliso Street, US 101 South for much of the mileage, and the overall profile is long-distance drive. At current regular gas prices, budget about $183.88 one way before food or hotel costs.
Trip Pace
Best split across 3 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
5 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
676.9 miles from Los Angeles, CA
A natural place for your longest stop of the day.
Drive Character
At 1353.8 miles and 19h 46m of driving, this is a route where fuel stops, weather, and timing matter more than any single turn. The main roads are North Main Street and East Aliso Street.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| North Main Street | 0 mi | 0m |
| East Aliso Street | 0 mi | 0m |
| US 101 South | 0 mi | 0m |
| Santa Ana Freeway | 0 mi | 0m |
| I 10 East | 0 mi | 0m |
| San Bernardino Freeway | 0 mi | 0m |
| I-10 | 0 mi | 0m |
| Pearl Harbor Memorial Highway | 0 mi | 0m |
Step-by-Step Directions
Start on West 1st Street
Turn left onto North Main Street
Turn right onto East Aliso Street
Take the ramp straight toward US 101 South, I 10 East, I 5 South
Merge slight left onto Santa Ana Freeway
Take the exit slight left toward I 10 East: San Bernardino
Continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight right to continue on San Bernardino Freeway
Keep slight left to continue on I-10 Metro ExpressLanes
Merge slight right onto San Bernardino Freeway
Continue on Pearl Harbor Memorial Highway
Keep slight left to continue on Sonny Bono Memorial Freeway
Keep slight left to continue on Sonny Bono Memorial Freeway
Continue on Pearl Harbor Memorial Highway
Continue on Papago Freeway
Continue on Dean Lindsey Memorial Tunnel
Continue on Papago Freeway
Keep slight left to continue on Papago Freeway
Merge slight right onto Maricopa Freeway
Continue on Phoenix-Casa Grande Highway
Continue on Casa Grande-Tucson Highway
Continue on North Freeway
Continue on Tucson-Benson Highway
Continue on Benson-Steins Pass Highway
Continue on Pearl Harbor Memorial Highway
Continue on Camino Real de Tierra Adentro
Continue straight
Keep slight right
Keep slight right
Keep slight right to continue on McDermott Freeway
Take the exit slight right toward Santa Rosa Street, Downtown
Turn straight onto North Pecos-La Trinidad
Keep slight right to continue on North Pecos-La Trinidad
Turn left onto Dolorosa Street
Arrive at your destination
When to Leave
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
Consider an overnight stop or starting very early.
Drive Plan
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 220 miles
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 676.9 miles
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 451 miles
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Last hour of driving
Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.
Before You Leave
Open the route before leaving Los Angeles, CA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Treat this as a 3-day road trip and book the overnight stop before the busiest arrival window.
Trip Strategy
Day 1
Settle into the route from Los Angeles, CA
Aim for roughly 451 miles and 6.6 hours of wheel time on this day.
Day 2
Keep the middle miles efficient
Aim for roughly 451 miles and 6.6 hours of wheel time on this day.
Day 3
Finish the approach into San Antonio, TX
Aim for roughly 451 miles and 6.6 hours of wheel time on this day.
Best Stop Towns on This Route
These towns line up with the pace of this drive and give you clearer places to stop with a purpose.
Late stop town
Coffee and fuel
338 mi into the route
Best for: Coffee, fuel, and an easy first stretch
This is a natural early stop once the first hours of the drive are behind you.
Late stop town
Overnight candidate
677 mi into the route
Best for: Hotel check-in, dinner, and a fresh start
This lines up well with a realistic day-end stop if you are breaking the drive into stages.
Late stop town
Final reset
1015 mi into the route
Best for: Food, fuel, and one last short break
This is a smart final reset before the arrival run into San Antonio, TX.
Suggested Overnight Stops
Night 1
451 mi · about 6.6h in
A practical overnight split lands near Chandler, AZ after about 451 miles or 6.6 hours of driving.
Night 2
903 mi · about 13.2h in
A practical overnight split lands near Fort Hancock, TX after about 903 miles or 13.2 hours of driving.
Travel Advice
Arrival Notes
Seasonal Notes
Stops Along the Way
Halfway Point
Midpoint
About 676.9 mi from Los Angeles, CA
A short stop after about 220 miles helps settle the day before fatigue starts building.
The midpoint is around 676.9 miles from Los Angeles, CA, which is a good place for a longer meal and fuel stop.
Overnight split
Hotel stopFor a steadier pace, wrap day one after about 451 miles or 6.6 hours on the road.
Final-third reset
Rest stopPlan one more short stretch-and-water break in the final third of the drive so the last arrival window feels easier.
These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| regular | $3.45 | $183.88 | $367.76 |
| midgrade | $3.85 | $205.20 | $410.40 |
| premium | $4.15 | $221.19 | $442.38 |
| diesel | $3.75 | $199.87 | $399.74 |
Based on 25.4 MPG average. Estimated CO2 emission: 473.7 kg one way.
Frequently Asked Questions
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