The drive from Crestwood, MO to Columbia, MO covers 119.9 miles and takes about 2h 28m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Dwight D Eisenhower Highway, Avenue of the Saints, I 270 for much of the mileage,
and the overall profile is turn-heavy local drive.
The longest uninterrupted segment is about 80.7 miles on Dwight D Eisenhower Highway.
At current regular gas prices, budget about $18.74 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
60 miles from Crestwood, MO
A natural place for your longest stop of the day
, about 1h 16m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 28m. Total distance: 119.9 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 28m drive, comfortable solo distance.
Scenic Drive
Turn-heavy local drive route profile with national parks nearby.
Drive Character
Expect a 2h 28m drive with frequent turns across 119.9 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 19 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dwight D Eisenhower Highway is the longest continuous segment at about 80.7 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes early in the drive.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 119.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: near the start: Lane positioning matters here; at 2.4 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 8.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 14 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
7
0 mi into trip|~0m in
Turn left
Lane positioning matters here
Use the left lane.
8
2.4 mi into trip|~5m in
Keep slight right at fork toward I 270: Memphis, Chicago
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight lane.
Toward I 270: Memphis, Chicago
8
8.8 mi into trip|~13m in
Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 12
Toward I 64, US 40, US 61: Wentzville, Saint Lo...
8
9 mi into trip|~14m in
Keep slight left at fork toward I 64 West, US 40 West, US 61 North: Wentzville
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left lane.
Toward I 64 West, US 40 West, US 61 North: Went...
8
34.9 mi into trip|~46m in|US 40
Take the exit onto US 40 toward I 70 West, US 40 West: Kansas City
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight left lanes.
Exit 1A
Toward I 70 West, US 40 West: Kansas City
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Crestwood, MO to Columbia, MO, road signs begin pointing toward Saint Louis along the way.
Saint Louis
8.8 mi in|~13m
Main Roads
Road
Distance
Duration
Dwight D Eisenhower Highway
80.7 mi
1h 35m
Avenue of the Saints
25.4 mi
30m
I 270
5.9 mi
7m
Sheriff Roger I. Wilson Memorial Highway
2 mi
2m
Watson Road
1.9 mi
3m
North Providence Road
1.2 mi
2m
US 40
0.6 mi
1m
Highway Patrol Sgt. Benjamin Booth Memorial Highway
0.5 mi
<1m
Longest stretch:
Dwight D Eisenhower Highway
— 80.7 mi, about 1h 35m
Turn-by-Turn Driving Directions
Step-by-step road directions between Crestwood, MO and Columbia, MO.
1
Start on MO 366
63 ft·7 sec·Watson Road
2
Turn left
378 ft·33 sec
Use the left lane.
3
Turn sharp left
330 ft·27 sec
4
Turn sharp right onto MO 366
1.9 mi·3 min·Watson Road
Use the left lane.
5
Take the ramp onto US Historic 66
0.4 mi·40 sec·US Historic 66
Toward I 44 West, I 270, US 50 West: Tulsa, Chicago, Memphis
6
Keep slight right at fork
0.1 mi·15 sec
Toward I 270: Memphis, ChicagoUse the straight lane.
7
Keep slight right at fork
0.4 mi·37 sec
Toward I 270 North: ChicagoUse the slight right lane.
8
Merge onto I 270
5.9 mi·7 min·I 270
9
Take the exit
0.1 mi·17 sec
Exit 12Toward I 64, US 40, US 61: Wentzville, Saint LouisUse the slight right lane.
10
Keep slight left at fork
0.4 mi·48 sec
Toward I 64 West, US 40 West, US 61 North: WentzvilleUse the slight left lane.
11
Continue on this road
0.1 mi·9 sec·this road
Exit 12Toward I 64 West, US 40 West, US 61 North: Wentzville
12
Merge onto I 64; US 40; US 61
25 mi·30 min·Avenue of the Saints
Use the straight lane.
13
Take the exit onto US 40
0.6 mi·1 min·US 40
Exit 1AToward I 70 West, US 40 West: Kansas CityUse the straight / slight left lanes.
14
Merge onto I 70; US 40
81 mi·1 hr 35 min·Dwight D Eisenhower Highway
15
Continue on I 70; US 40
2.0 mi·2 min·Sheriff Roger I. Wilson Memorial Highway
16
Continue on I 70; US 40
0.5 mi·34 sec·Highway Patrol Sgt. Benjamin Booth Memorial Highway
17
Take the exit
0.1 mi·15 sec
Exit 126Toward MO 163: Downtown
18
Turn left onto MO 163
1.2 mi·2 min·North Providence Road
19
Arrive at destination
MO 163
Trip Plan
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 60 miles from Crestwood, MO, or about 1h 16m into the drive.
The longest continuous stretch on this route runs about 80.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 26 miles or 35m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 60 miles or 1h 16m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 1m
Traffic, exits, and arrival timing usually matter more near Columbia, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Crestwood, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Crestwood, MO
This is one driving day of about 119.9 miles and 2h 28m.
Your first comfortable stop window is around 26 miles from Crestwood, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Dwight D Eisenhower Highway for about 80.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 60 mi from Crestwood, MO
· 1h 16m into the drive
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $13 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
36
0
$12.59
$5.76
Efficient EV
30
0
$10.49
$4.80
EV Truck/SUV
48
0
$16.79
$7.67
Gas CO2
42 kg
EV CO2
14 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 14, 2026
Origin
Crestwood, MO
Night
in Crestwood on Friday
Local time
9:38 PM
CDT
Current temp
55°F
Unavailable
Live forecast
Destination
Columbia, MO
Night
in Columbia on Friday
Local time
9:38 PM
CDT
Current temp
64°F
Slight Chance Showers And Thunderstorms
S 12 mph15% chanceLive forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
9 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 28m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Crestwood, MO to Columbia, MO covers 119.9 miles and takes about 2h 28m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Dwight D Eisenhower Highway, Avenue of the Saints, I 270. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 60 miles from Crestwood, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $18.74 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a demanding drive. With 14 significant decision points across 119.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: near the start: Lane positioning matters here; at 2.4 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 8.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
On the drive from Crestwood, MO to Columbia, MO, road signs begin pointing toward Saint Louis along the way.
Yes. Nearby national parks include Gateway Arch National Park.
How this page is built
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, NREL for EV charging, and NPS for national parks. See our methodology for refresh cadence and limitations.
