Origin
Doniphan, MO
Afternoon in Doniphan on Sunday
Local time
3:46 PM
CDT
Current temp
62°F
Unavailable
Live forecast
Trip from Doniphan, MO to St. Louis, MO
Drive Time
3h 34m
Distance
178.4 mi
287 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$27
one way
EV Charging
Loading...
station data
Best Time to Leave
4 AM
3h 22m
★
6 AM
3h 35m
8 AM
3h 59m
10 AM
3h 43m
12 PM
3h 41m
3 PM
3h 45m
5 PM
3h 58m
8 PM
3h 27m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Doniphan, MO
Lena Khrupina
Trip Overview
The drive from Doniphan, MO to St. Louis, MO covers 178.4 miles and takes about 3h 34m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on US 67, I 55, US 160 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 124.1 miles on US 67. At current regular gas prices, budget about $27.10 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
89.2 miles from Doniphan, MO
A natural place for your longest stop of the day , about 1h 49m into the drive .
Drive Character
This is a 3h 34m highway drive covering 178.4 miles, with most of the trip on US 67 and I 55. The longest continuous stretch is about 124.1 miles on US 67.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 16 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 67 is the longest continuous segment at about 124.1 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on US 67 and I 55. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near MO 142 / Walnut Street.
Route Complexity
6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
This drive requires moderate attention. Across 178.4 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (MO 142 / Walnut Street): Navigation decision point; at 29.7 miles (US 67): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 143 miles (US 67): Highway fork - watch signs carefully.
Critical Maneuvers
5 of 11 key pointsThese are the spots where you need to pay the most attention. Preview them before you drive.
4
0 mi into trip
|
~0m in
|
MO 142 / Walnut Street
Turn right onto MO 142 / Walnut Street
Navigation decision point
5
29.7 mi into trip
|
~40m in
|
US 67
Take the exit onto US 67 toward US 60 West, US 67 North: Springfield
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 60 West, US 67 North: Springfield
4
143 mi into trip
|
~2h 51m in
|
US 67
Keep slight right at fork onto US 67
Highway fork - watch signs carefully
4
143.4 mi into trip
|
~2h 51m in
Take the exit toward I 55 North: Saint Louis
Exit ramp - move to the correct lane early
Toward I 55 North: Saint Louis
7
176.7 mi into trip
|
~3h 30m in
Take the exit toward MO 30 East: Gravois Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 207A
Toward MO 30 East: Gravois Avenue
Main Roads
| Road | Distance | Duration |
|---|---|---|
| US 67 | 124.1 mi | 2h 22m |
| I 55 | 20.5 mi | 22m |
| US 160 | 18.4 mi | 27m |
| Rosa Parks Highway | 12.5 mi | 15m |
| South Tucker Boulevard | 1.3 mi | 3m |
| Walnut Street | 0.7 mi | 1m |
| Gravois Avenue | 0.2 mi | <1m |
| Plum Street | <0.1 mi | <1m |
Longest stretch:
US 67
— 124.1 mi, about 2h 22m
Turn-by-Turn Driving Directions
Step-by-step road directions between Doniphan, MO and St. Louis, MO.
1
Start on Plum Street
169 ft
·
9 sec
·
Plum Street
2
Turn right onto MO 142
0.7 mi
·
1 min
·
Walnut Street
3
Turn right onto US 160; MO 21
18 mi
·
27 min
·
US 160; MO 21
4
Turn left onto US 160
97 ft
·
1 sec
·
US 160
5
Take the ramp
0.2 mi
·
24 sec
6
Merge onto US 67
10 mi
·
11 min
·
US 67
7
Take the exit onto US 67
113 mi
·
2 hr 10 min
·
US 67
Toward US 60 West, US 67 North: Springfield
8
Keep slight right at fork onto US 67
0.3 mi
·
27 sec
·
US 67
9
Take the exit
0.3 mi
·
49 sec
Toward I 55 North: Saint Louis
10
Merge onto I 55
21 mi
·
22 min
·
I 55
11
Continue on I 55
12 mi
·
15 min
·
Rosa Parks Highway
Use the none lane.
12
Take the exit
0.2 mi
·
23 sec
Exit 207A
Toward MO 30 East: Gravois Avenue
Use the slight right lane.
13
Turn slight right onto Gravois Avenue
0.2 mi
·
27 sec
·
Gravois Avenue
14
Continue on South Tucker Boulevard
1.3 mi
·
3 min
·
South Tucker Boulevard
Use the none lane.
15
Turn right onto Market Street
86 ft
·
2 sec
·
Market Street
16
Arrive at destination
Market Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 89.2 miles from Doniphan, MO, or about 1h 49m into the drive.
The longest continuous stretch on this route runs about 124.1 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 38m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 89.2 miles or 1h 49m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 55m
Traffic, exits, and arrival timing usually matter more near St. Louis, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Doniphan, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Doniphan, MO
This is one driving day of about 178.4 miles and 3h 34m.
Your first comfortable stop window is around 80 miles from Doniphan, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 67 for about 124.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 89.2 mi from Doniphan, MO · 1h 49m into the drive
Mid-route town
Meal stop
89 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 80 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 89.2 miles from Doniphan, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before US 67 if your tank is already low. That segment runs about 124.1 miles.
Arriving in St. Louis, MO
The final approach into St. Louis, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around St. Louis, MO.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$27.10 one way
$54.19 round trip
$3.86/gal
25.4 MPG avg
62 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $29.87 | $59.74 |
| premium | $4.80 | $33.68 | $67.36 |
| diesel | $5.64 | $39.63 | $79.27 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$27
Meals
$25–$50
Total
$52–$77
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 62.4 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $19 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 53.5 | 0 | $18.73 | $8.56 |
| Efficient EV | 44.6 | 0 | $15.61 | $7.14 |
| EV Truck/SUV | 71.4 | 0 | $24.98 | $11.42 |
Gas CO2
62 kg
EV CO2
21 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
St. Louis, MO
Afternoon in St. Louis on Sunday
Local time
3:46 PM
CDT
Current temp
74°F
Slight Chance Rain Showers
SE 8 mph
20% chance
Live forecast
Flood Warning
Flood Warning issued April 11 at 11:35AM CDT by NWS St Louis MO
Flood Warning
Flood Warning issued April 11 at 11:35AM CDT by NWS St Louis MO
Along the Route
73°F
Campton, IL
89 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
12 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 34m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Doniphan, MO to St. Louis, MO covers 178.4 miles and takes about 3h 34m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US 67, I 55, US 160. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 89.2 miles from Doniphan, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $27.10 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This drive requires moderate attention. Across 178.4 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
The main spots that need attention: near the start (MO 142 / Walnut Street): Navigation decision point; at 29.7 miles (US 67): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 143 miles (US 67): Highway fork - watch signs carefully.
The route from Doniphan, MO to St. Louis, MO does not surface many named destination signs beyond the main corridor.
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