Origin
East Independence, MO
Afternoon in East Independence on Sunday
Local time
2:28 PM
CDT
Current temp
49°F
Unavailable
Live forecast
Trip from East Independence, MO to Clarkton, MO
Drive Time
8h 4m
Distance
416.4 mi
670 km
Drive Score
7/10
Good drive
Same Day?
2-day trip
Fuel Cost
$63
one way
East Independence, MO
Ankit Rainloure
Trip Overview
The drive from East Independence, MO to Clarkton, MO covers 416.4 miles and takes about 8h 4m behind the wheel. It usually feels better as a 2-day road trip than as one long push.
The route leans on Main Road, East Truman Road, Holke Road for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $63.25 one way before food or hotel costs.
Trip Pace
Best split across 2 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
208.2 miles from East Independence, MO
A natural place for your longest stop of the day , about 4h 2m into the drive .
Drive Character
Expect a 8h 4m drive with frequent turns across 416.4 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 35 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Main Road is one of the defining roads on this drive.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Route Complexity
4/10
Easy - simple navigation with a manageable amount of wheel time
The route itself is not hard, but at 8h 4m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from East Independence, MO to Clarkton, MO is straightforward, with well-signed roads and simple exits.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| Main Road | Unavailable | Refreshing |
| East Truman Road | Unavailable | Refreshing |
| Holke Road | Unavailable | Refreshing |
| South Jackson Drive | Unavailable | Refreshing |
| East R | Unavailable | Refreshing |
| South Little Blue Parkway | Unavailable | Refreshing |
| Little Blue Parkway | Unavailable | Refreshing |
| Dwight D | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Longest stretch:
Main Road
— detailed segment metrics are refreshing.
Turn-by-Turn Driving Directions
Step-by-step road directions between East Independence, MO and Clarkton, MO.
1
Start on East 9th Street South
79 ft
·
9 sec
·
East 9th Street South
2
Turn left onto Main Road
0.3 mi
·
1 min
·
Main Road
3
Turn left onto East Truman Road
0.7 mi
·
1 min
·
East Truman Road
4
Turn right onto Holke Road
0.9 mi
·
1 min
·
Holke Road
5
Turn straight onto South Jackson Drive
1.2 mi
·
2 min
·
South Jackson Drive
6
Turn left onto East R.D. Mize Road
0.2 mi
·
37 sec
·
East R.D. Mize Road
7
Turn right onto South Little Blue Parkway
1.7 mi
·
3 min
·
South Little Blue Parkway
8
Take the ramp left toward Little Blue Parkway, 39th Street, Mall Entrance
0.3 mi
·
38 sec
·
Little Blue Parkway, 39th Street, Mall Entrance
9
Continue on Dwight D. Eisenhower Highway
53 mi
·
56 min
·
Dwight D. Eisenhower Highway
10
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi
·
34 min
·
U.S. Submarine Veterans' Memorial Highway
11
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22 mi
·
24 min
·
U.S. Submarine Veterans' Memorial Highway
12
Continue on Dwight D. Eisenhower Highway
1.8 mi
·
2 min
·
Dwight D. Eisenhower Highway
13
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi
·
1 min
·
Highway Patrol Sgt. Benjamin Booth Memorial Highway
14
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi
·
2 min
·
Sheriff Roger I. Wilson Memorial Highway
15
Continue on Dwight D. Eisenhower Highway
81 mi
·
1 hr 35 min
·
Dwight D. Eisenhower Highway
16
Take the exit slight right toward I 64 East, US 40 East, US 61 South: Chesterfield
0.3 mi
·
33 sec
·
I 64 East, US 40 East, US 61 South: Chesterfield
17
Merge slight left onto Avenue of the Saints
25 mi
·
30 min
·
Avenue of the Saints
18
Take the exit slight right toward I 270: Chicago, Memphis
0.3 mi
·
39 sec
·
I 270: Chicago, Memphis
19
Keep slight right to continue on I 270 South: Memphis
0.3 mi
·
31 sec
·
I 270 South: Memphis
20
Merge slight left
11 mi
·
14 min
21
Take the exit slight right toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
0.4 mi
·
27 sec
·
I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
22
Keep slight right to continue on I 55 South: Memphis
0.4 mi
·
44 sec
·
I 55 South: Memphis
23
Merge slight left onto Rosa Parks Highway
1.5 mi
·
1 min
·
Rosa Parks Highway
24
Continue on Officer Thomas G. Smith, Jr. Memorial Highway
1.8 mi
·
2 min
·
Officer Thomas G. Smith, Jr. Memorial Highway
25
Continue on Police Officer Steven Jarvis Memorial Highway
127 mi
·
2 hr 15 min
·
Police Officer Steven Jarvis Memorial Highway
26
Take the exit slight right toward US 60 West: Dexter, Poplar Bluff
0.5 mi
·
1 min
·
US 60 West: Dexter, Poplar Bluff
27
Merge slight left
23 mi
·
26 min
28
Take the exit slight right toward MO 25, US 60 Business: Dexter, Bloomfield
0.3 mi
·
41 sec
·
MO 25, US 60 Business: Dexter, Bloomfield
29
Turn left
21 mi
·
31 min
30
Continue straight
4.4 mi
·
6 min
31
Turn left
0.3 mi
·
39 sec
32
Continue straight
0.1 mi
·
18 sec
33
Continue on North Main Street
0.5 mi
·
1 min
·
North Main Street
34
Turn left onto East Clark Street
108 ft
·
5 sec
·
East Clark Street
35
Arrive at your destination
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This drive is better paced as a 2-day trip.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 208.2 miles from East Independence, MO, or about 4h 2m into the drive.
Consider an overnight stop or starting very early.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 92 miles or 1h 46m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 208.2 miles or 4h 2m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 208.2 miles or 4h 2m
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Final hour starts around 6h 54m
Traffic, exits, and arrival timing usually matter more near Clarkton, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving East Independence, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
+
Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.
Day 1
Settle into the route from East Independence, MO
Aim for roughly 208 miles and 4 hours of wheel time on this day.
Day 2
Finish the approach into Clarkton, MO
Aim for roughly 208 miles and 4 hours of wheel time on this day.
Your first comfortable stop window is around 92 miles from East Independence, MO.
This route usually feels better as a 2-day drive than as one long push.
Plan about 2 real breaks rather than only quick fuel stops.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 208.2 mi from East Independence, MO · 4h 2m into the drive
Mid-route town
Overnight candidate
208 mi into the route
Best for: Hotel check-in, dinner, and a fresh start
This lines up well with a realistic day-end stop if you are breaking the drive into stages.
Find hotels in East Saint Louis, ILOvernight Options
Night 1
208 mi · about 4h in
A practical overnight split lands near East Saint Louis, IL after about 208 miles or 4 hours of driving.
Find hotelsPacing Suggestions
Fuel and coffee
A short stop after about 92 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 208.2 miles from East Independence, MO, which is a good place for a longer meal and fuel stop.
Overnight split
Hotel stopFor a steadier pace, wrap day one after about 208 miles or 4 hours on the road.
Arriving in Clarkton, MO
The final approach into Clarkton, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Clarkton, MO.
On a multi-day trip, keep the last day a little lighter so you reach Clarkton, MO with some flexibility left in the schedule.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$63.25 one way
$126.49 round trip
$3.86/gal
25.4 MPG avg
146 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $69.72 | $139.44 |
| premium | $4.80 | $78.61 | $157.22 |
| diesel | $5.64 | $92.51 | $185.02 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$63
Hotel (1n)
$80–$140
Meals
$50–$100
Total
$193–$303
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 145.7 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $44 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 124.9 | 1 | $43.72 | $19.99 |
| Efficient EV | 104.1 | 1 | $36.43 | $16.66 |
| EV Truck/SUV | 166.6 | 2 | $58.30 | $26.65 |
Gas CO2
146 kg
EV CO2
49 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Clarkton, MO
Afternoon in Clarkton on Sunday
Local time
2:28 PM
CDT
Current temp
64°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
15 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
8h 4m on the road
This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from East Independence, MO to Clarkton, MO covers 416.4 miles and takes about 8h 4m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Main Road, East Truman Road, Holke Road. Expect a mix of highway and local road driving.
Consider an overnight stop or starting very early.
Yes. This route is usually more comfortable as a 2-day drive. A sensible stopping point is after roughly 208 miles on day one.
The midpoint is about 208.2 miles from East Independence, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $63.25 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
The route itself is not hard, but at 8h 4m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
This route does not have any notably tricky sections. Most of the drive from East Independence, MO to Clarkton, MO is straightforward, with well-signed roads and simple exits.
The route from East Independence, MO to Clarkton, MO does not surface many named destination signs beyond the main corridor.
Was this route helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore More
More trips to Clarkton, MO
Explore more options from East Independence, MO or browse trips ending in Clarkton, MO.
Looking for more statewide routes? Browse MO road trips.
Explore maps for East Independence, MO or Clarkton, MO on MapSof.net.