The drive from Enid, OK to Panama, OK covers 233.2 miles and takes about 4h 9m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Cimarron Turnpike, Muskogee Turnpike, Trooper Chris Van Krevelen Memorial Highway for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 59 miles on Cimarron Turnpike.
At current regular gas prices, budget about $36.46 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
116.6 miles from Enid, OK
A natural place for your longest stop of the day
, about 2h 3m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h 9m. Total distance: 233.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 9m drive, comfortable solo distance.
Drive Character
This is a 4h 9m highway drive covering 233.2 miles, with most of the trip on Cimarron Turnpike and Muskogee Turnpike. The longest continuous stretch is about 59 miles on Cimarron Turnpike.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 28 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Cimarron Turnpike is the longest continuous segment at about 59 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on Cimarron Turnpike and Muskogee Turnpike. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 45.8 miles in.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 233.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 45.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 45.9 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 115.2 miles (US 64; OK 51 / Inner Dispersal Loop): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 18 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
8
45.8 mi into trip|~51m in
Take the exit toward US 177: Stillwater, Ponca City
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 15
Toward US 177: Stillwater, Ponca City
8
45.9 mi into trip|~51m in
Keep slight left at fork
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / right lanes.
Exit 15
8
115.2 mi into trip|~2h 1m in|US 64; OK 51 / Inner Dispersal Loop
Take the exit onto US 64; OK 51 / Inner Dispersal Loop toward US 75 North, US 64 East, OK 51 East: Broken Arrow
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the left lane.
Exit 4B
Toward US 75 North, US 64 East, OK 51 East: Bro...
8
116.4 mi into trip|~2h 3m in|US 64; OK 51 / Broken Arrow Expressway
Keep slight right at fork onto US 64; OK 51 / Broken Arrow Expressway toward US 64 East, OK 51 East: Broken Arrow
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight lane.
Toward US 64 East, OK 51 East: Broken Arrow
8
208.1 mi into trip|~3h 37m in|I 40 Business
Take the exit onto I 40 Business toward I 40 Business East, US 59: Sallisaw, Poteau
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 308
Toward I 40 Business East, US 59: Sallisaw, Pot...
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Enid, OK and Panama, OK, road signs point toward Ponca City, Okmulgee, Oklahoma City, Bartlesville, Fort Smith and Poteau.
Ponca City
45.8 mi in|~51m
Okmulgee
114.4 mi in|~1h 59m|via US 64; OK 51
Oklahoma City
114.4 mi in|~1h 59m|via US 64; OK 51
Bartlesville
115.5 mi in|~2h 1m|via US 64; US 75; OK 51
Fort Smith
131.2 mi in|~2h 21m|via OK 351
Poteau
208.1 mi in|~3h 37m|via I 40 Business
Main Roads
Road
Distance
Duration
Cimarron Turnpike
59 mi
56m
Muskogee Turnpike
55.3 mi
53m
Trooper Chris Van Krevelen Memorial Highway
24.1 mi
25m
Vietnam Veteran's Memorial Highway
20.7 mi
21m
Kerr Boulevard
20 mi
23m
Sand Springs Expressway
14.4 mi
16m
Broken Arrow Expressway
11.8 mi
14m
Keystone Expressway
8.6 mi
9m
Longest stretch:
Cimarron Turnpike
— 59 mi, about 56m
Turn-by-Turn Driving Directions
Step-by-step road directions between Enid, OK and Panama, OK.
1
Start on South Grand Avenue
0.3 mi·1 min·South Grand Avenue
2
Turn left onto US 412; CR E0430
6.4 mi·9 min·East Owen K. Garriott Road
Use the straight lane.
3
Continue on US 64; US 412; CR E0425
24 mi·25 min·Trooper Chris Van Krevelen Memorial Highway
Use the straight lane.
4
Continue on US 412
15 mi·14 min·Cimarron Turnpike
Toward US 412 East: TulsaUse the straight / slight right lanes.
5
Take the exit
0.1 mi·7 sec
Exit 15Toward US 177: Stillwater, Ponca CityUse the straight / slight right lanes.
6
Keep slight left at fork
0.2 mi·12 sec
Exit 15Use the straight / right lanes.
7
Merge onto US 412
44 mi·41 min·Cimarron Turnpike
Use the straight lane.
8
Continue on US 412
5.0 mi·5 min·Keystone Expressway
Use the straight lane.
9
Continue on US 64; US 412
1.2 mi·1 min·Jerald Warden Memorial Highway
Use the straight lane.
10
Continue on US 64; US 412
3.6 mi·3 min·Keystone Expressway
Use the straight lane.
11
Continue on US 64; US 412
14 mi·16 min·Sand Springs Expressway
Use the straight / slight right lanes.
12
Take the exit onto US 64; OK 51
0.2 mi·26 sec·US 64; OK 51
Toward I 244 West, US 64 East, OK 51 East, US 75 South: Broken Arrow, Okmulgee, Oklahoma CityUse the right lane.
13
Merge onto I 244; US 64; OK 51
0.6 mi·49 sec·Martin Luther King, Junior Memorial Expressway
14
Take the exit onto US 64; OK 51
0.3 mi·35 sec·Inner Dispersal Loop
Exit 4BToward US 75 North, US 64 East, OK 51 East: Broken ArrowUse the left lane.
15
Continue on US 64; US 75; OK 51
1.0 mi·1 min·Broken Arrow Expressway
Toward US 75 North, US 64 East, OK 51 East: Broken Arrow, BartlesvilleUse the straight / slight right lanes.
16
Keep slight right at fork onto US 64; OK 51
11 mi·13 min·Broken Arrow Expressway
Toward US 64 East, OK 51 East: Broken ArrowUse the straight lane.
17
Continue on OK 51
379 ft·5 sec·Representative David Brumbaugh Memorial Bridge
18
Continue on OK 51
3.8 mi·4 min·Disabled American Veterans Highway
Use the straight lane.
19
Continue on OK 351
55 mi·53 min·Muskogee Turnpike
Toward OK 351 East: Muskogee, Fort SmithUse the straight / slight right lanes.
20
Keep slight left at fork
0.9 mi·1 min
Exit 56BToward I 40 East: Fort Smith
21
Merge onto I 40
21 mi·21 min·Vietnam Veteran's Memorial Highway
Use the straight lane.
22
Take the exit onto I 40 Business
0.2 mi·31 sec·I 40 Business
Exit 308Toward I 40 Business East, US 59: Sallisaw, PoteauUse the straight / slight right lanes.
23
Turn right onto US 59
20 mi·23 min·Kerr Boulevard
Use the right lane.
24
Turn right onto US 59; US 271
359 ft·7 sec·US 59; US 271
25
Continue on US 59; US 271
0.1 mi·10 sec·US 59; US 271
Use the straight / left lanes.
26
Continue on US 59; US 271
4.7 mi·7 min·US 59; US 271
Use the straight / left / right lanes.
27
Turn left onto Main Street
62 ft·1 sec·Main Street
Use the left lane.
28
Arrive at destination
Main Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 116.6 miles from Enid, OK, or about 2h 3m into the drive.
The longest continuous stretch on this route runs about 59 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 51 miles or 56m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 116.6 miles or 2h 3m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 20m
Traffic, exits, and arrival timing usually matter more near Panama, OK than in the middle of the route.
Before You Leave
+
Open the route before leaving Enid, OK so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Enid, OK
This is one driving day of about 233.2 miles and 4h 9m.
Your first comfortable stop window is around 51 miles from Enid, OK.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Cimarron Turnpike for about 59 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 116.6 mi from Enid, OK
· 2h 3m into the drive
Place data sourced from public business listings. Hours and availability may vary.
Fuel & Cost
Regular Gas
$36.46 one way
$72.92 round trip
$3.97/gal25.4 MPG avg82 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$40.03
$80.06
premium
$4.89
$44.88
$89.75
diesel
$5.61
$51.49
$102.98
Estimated Tolls: $6.81
Muskogee Turnpike
(55.3 mi)$3.87
Cimarron Turnpike
(59 mi)$2.94
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$36
Tolls
$7
Meals
$25–$50
Total
$68–$93
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 81.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $24 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
70
0
$24.49
$11.19
Efficient EV
58.3
0
$20.40
$9.33
EV Truck/SUV
93.3
1
$32.65
$14.92
Gas CO2
82 kg
EV CO2
27 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Enid, OK
Morning
in Enid on Friday
Local time
6:32 AM
CDT
Current temp
74°F
Unavailable
Live forecast
Destination
Panama, OK
Morning
in Panama on Friday
Local time
6:32 AM
CDT
Current temp
55°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
19 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 9m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Enid, OK to Panama, OK covers 233.2 miles and takes about 4h 9m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Cimarron Turnpike, Muskogee Turnpike, Trooper Chris Van Krevelen Memorial Highway. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 116.6 miles from Enid, OK. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $36.46 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 18 significant decision points across 233.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 45.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 45.9 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 115.2 miles (US 64; OK 51 / Inner Dispersal Loop): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Enid, OK and Panama, OK, road signs point toward Ponca City, Okmulgee, Oklahoma City, Bartlesville, Fort Smith and Poteau.
How this page is built
Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from
OSRM
over
OpenStreetMap.
Fuel cost uses
EIA
weekly regional averages.
Pages are published only after passing our data-quality checks; our
methodology page
documents refresh cadence, editorial standards, and known limitations.
