The drive from Festus, MO to Independence, MO covers 261.5 miles and takes about 5h 3m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Dwight D. Eisenhower Highway for much of the mileage,
and the overall profile is turn-heavy local drive.
The longest uninterrupted segment is about 80.7 miles on Dwight D Eisenhower Highway.
At current regular gas prices, budget about $40.88 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
130.7 miles from Festus, MO
A natural place for your longest stop of the day
, about 2h 37m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 3m. Total distance: 261.5 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 3m drive, comfortable solo distance.
Scenic Drive
Turn-heavy local drive route profile with national parks nearby.
Drive Character
Expect a 5h 3m drive with frequent turns across 261.5 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 31 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dwight D Eisenhower Highway is the longest continuous segment at about 80.7 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 21.9 miles in.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 261.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 21.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 22.1 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 34.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 18 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
8
21.9 mi into trip|~25m in
Take the exit toward I 270 West, I 255 East: Kansas City, Chicago
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 196
Toward I 270 West, I 255 East: Kansas City, Chi...
8
22.1 mi into trip|~26m in
Keep slight left at fork toward I 270 West: Kansas City
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left lane.
Toward I 270 West: Kansas City
8
34.4 mi into trip|~41m in
Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 12
Toward I 64, US 40, US 61: Wentzville, Saint Lo...
8
34.6 mi into trip|~42m in
Keep slight left at fork toward I 64 West, US 40 West, US 61 North: Wentzville
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left lane.
Toward I 64 West, US 40 West, US 61 North: Went...
8
60.5 mi into trip|~1h 14m in|US 40
Take the exit onto US 40 toward I 70 West, US 40 West: Kansas City
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight left lanes.
Exit 1A
Toward I 70 West, US 40 West: Kansas City
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Festus, MO and Independence, MO, road signs point toward Chicago and Saint Louis.
Chicago
21.9 mi in|~25m
Saint Louis
34.4 mi in|~41m
Main Roads
Road
Distance
Duration
Dwight D Eisenhower Highway
80.7 mi
1h 35m
U.S. Submarine Veterans' Memorial Highway
54.4 mi
58m
Dwight D. Eisenhower Highway
54.3 mi
58m
Avenue of the Saints
25.4 mi
30m
I 55
19 mi
20m
I 270
11.5 mi
14m
South Noland Road
3 mi
5m
Truman/Eisenhower Presidential Highway
2.7 mi
3m
Longest stretch:
Dwight D Eisenhower Highway
— 80.7 mi, about 1h 35m
Turn-by-Turn Driving Directions
Step-by-step road directions between Festus, MO and Independence, MO.
1
Start on North 2nd Street
77 ft·5 sec·North 2nd Street
2
Turn right onto Walnut Street
339 ft·20 sec·Walnut Street
3
Turn left onto West Main Street
0.1 mi·16 sec·West Main Street
4
Turn right onto South Mill Street
0.6 mi·59 sec·South Mill Street
5
Turn right onto MO A
0.5 mi·57 sec·Veterans Memorial Boulevard
6
Take the ramp
0.3 mi·37 sec
Toward I 55 North: Saint Louis
7
Merge onto I 55
19 mi·20 min·I 55
8
Continue on I 55
1.3 mi·1 min·Rosa Parks Highway
9
Take the exit
0.2 mi·27 sec
Exit 196Toward I 270 West, I 255 East: Kansas City, ChicagoUse the slight right lane.
10
Keep slight left at fork
388 ft·8 sec
Toward I 270 West: Kansas CityUse the slight left lane.
11
Continue on this road
0.7 mi·1 min·this road
Exit 196Toward I 270 West
12
Merge onto I 270
11 mi·14 min·I 270
Use the straight lane.
13
Take the exit
0.1 mi·17 sec
Exit 12Toward I 64, US 40, US 61: Wentzville, Saint LouisUse the slight right lane.
14
Keep slight left at fork
0.4 mi·48 sec
Toward I 64 West, US 40 West, US 61 North: WentzvilleUse the slight left lane.
15
Continue on this road
0.1 mi·9 sec·this road
Exit 12Toward I 64 West, US 40 West, US 61 North: Wentzville
16
Merge onto I 64; US 40; US 61
25 mi·30 min·Avenue of the Saints
Use the straight lane.
17
Take the exit onto US 40
0.6 mi·1 min·US 40
Exit 1AToward I 70 West, US 40 West: Kansas CityUse the straight / slight left lanes.
18
Merge onto I 70; US 40
81 mi·1 hr 35 min·Dwight D Eisenhower Highway
19
Continue on I 70; US 40
2.0 mi·2 min·Sheriff Roger I. Wilson Memorial Highway
20
Continue on I 70; US 40
1.6 mi·1 min·Highway Patrol Sgt. Benjamin Booth Memorial Highway
21
Continue on I 70; US 40
1.8 mi·2 min·Dwight D. Eisenhower Highway
22
Continue on I 70; US 40
54 mi·58 min·U.S. Submarine Veterans' Memorial Highway
Place data sourced from public business listings. Hours and availability may vary.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $27 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
78.5
0
$27.46
$12.55
Efficient EV
65.4
0
$22.88
$10.46
EV Truck/SUV
104.6
1
$36.61
$16.74
Gas CO2
91 kg
EV CO2
31 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Festus, MO
Evening
in Festus on Thursday
Local time
8:21 PM
CDT
Current temp
56°F
Unavailable
Live forecast
Destination
Independence, MO
Evening
in Independence on Thursday
Local time
8:21 PM
CDT
Current temp
73°F
Unavailable
Live forecast
74°F
Washington, MO
131 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
17 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 3m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Festus, MO to Independence, MO covers 261.5 miles and takes about 5h 3m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Dwight D Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Dwight D. Eisenhower Highway. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 130.7 miles from Festus, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $40.88 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 18 significant decision points across 261.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 21.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 22.1 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 34.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Festus, MO and Independence, MO, road signs point toward Chicago and Saint Louis.
Yes. Nearby national parks include Gateway Arch National Park and Ste. Geneviève National Historical Park.
