Trip from Greenville, MS to Saltillo, MS

Drive Time

4h 10m

Distance

195.7 mi

315 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$30

one way

EV Charging

station data

Best Time to Leave

Save up to 39 min

4 AM

3h 58m ★

6 AM

4h 11m

8 AM

4h 37m

10 AM

4h 20m

12 PM

4h 17m

3 PM

4h 21m

5 PM

4h 36m

8 PM

4h 3m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly

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Greenville, MS

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Saltillo, MS

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Trip Overview

The drive from Greenville, MS to Saltillo, MS covers 195.7 miles and takes about 4h 10m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on US 278, US 61, MS 9 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 92.3 miles on US 278. At current regular gas prices, budget about $29.92 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

97.8 miles from Greenville, MS

A natural place for your longest stop of the day , about 2h 5m into the drive .

Drive Character

This is a 4h 10m highway drive covering 195.7 miles, with most of the trip on US 278 and US 61. The longest continuous stretch is about 92.3 miles on US 278.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.

There are about 25 navigation steps in the underlying route data, so the final approach matters more than the middle miles.

US 278 is the longest continuous segment at about 92.3 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on US 278 and US 61. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 76.6 miles in near US 278.

Route Complexity 9/10

High effort - long or complex enough to need steady focus all day

This is a demanding drive. With 17 significant decision points across 195.7 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 76.6 miles (US 278): Highway fork - watch signs carefully. Lane positioning matters here; at 168.5 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 168.9 miles: Highway fork - watch signs carefully.

Critical Maneuvers

5 of 17 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

76.6 mi into trip | ~1h 38m in | US 278

Keep slight right at fork onto US 278

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight lane.

168.5 mi into trip | ~3h 35m in

Take the exit toward MS 9: Pontotoc, Sherman

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Toward MS 9: Pontotoc, Sherman

168.9 mi into trip | ~3h 36m in

Keep slight left at fork toward MS 9 North: Sherman

Highway fork - watch signs carefully

Toward MS 9 North: Sherman

168.9 mi into trip | ~3h 36m in | MS 9

Turn left onto MS 9

Lane positioning matters here

Use the straight lane.

178.7 mi into trip | ~3h 47m in

Take the exit toward I-22 East, US 78 East: Tupelo

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the right lane. Toward I-22 East, US 78 East: Tupelo

Towns Along This Route

On the drive from Greenville, MS to Saltillo, MS, road signs begin pointing toward Sherman along the way.

Sherman

168.5 mi in | ~3h 35m

Main Roads

Road	Distance	Duration
US 278	92.3 mi	1h 57m
US 61	64.4 mi	1h 18m
MS 9	9.8 mi	11m
I 22	9.2 mi	9m
MS 182	8.7 mi	12m
US 45	5.6 mi	6m
South Broad Street	1.4 mi	2m
Main Street	0.9 mi	2m

Longest stretch: US 278 — 92.3 mi, about 1h 57m

Turn-by-Turn Driving Directions

Step-by-step road directions between Greenville, MS and Saltillo, MS.

Start on South Broadway Street

10 ft · 8 sec · South Broadway Street

Turn left onto Main Street

0.9 mi · 2 min · Main Street

Turn left

8.7 mi · 12 min

Turn left onto South Broad Street

1.4 mi · 2 min · South Broad Street

Turn straight onto Old Hwy 61

0.8 mi · 1 min · Old Hwy 61

At the end of the road, turn right onto Griffin Road

144 ft · 3 sec · Griffin Road

Turn left

64 mi · 1 hr 18 min

Take the exit slight right

0.4 mi · 50 sec

Keep slight right

92 mi · 1 hr 56 min

Take the exit slight right toward MS 9: Pontotoc, Sherman

0.3 mi · 50 sec · MS 9: Pontotoc, Sherman

Keep slight left to continue on MS 9 North: Sherman

236 ft · 12 sec · MS 9 North: Sherman

Turn left

9.8 mi · 11 min

Take the exit right toward I-22 East, US 78 East: Tupelo

0.2 mi · 28 sec · I-22 East, US 78 East: Tupelo

Merge slight left

9.2 mi · 9 min

Take the exit slight right toward US 45:north: Corinth

0.2 mi · 32 sec · US 45:north: Corinth

Merge slight left

5.6 mi · 6 min

Take the exit slight right

0.3 mi · 45 sec

Keep slight right

341 ft · 8 sec

Turn straight

0.2 mi · 22 sec

Turn slight right

453 ft · 20 sec

Continue straight

377 ft · 20 sec

Turn left onto Kyle Avenue

0.3 mi · 1 min · Kyle Avenue

At the end of the road, turn left

0.5 mi · 2 min

Continue on East Mobile Street

502 ft · 10 sec · East Mobile Street

Arrive at your destination

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.

Plan roughly 1 meaningful break for fuel, food, and rest.

The halfway point lands around 97.8 miles from Greenville, MS, or about 2h 5m into the drive.

The longest continuous stretch on this route runs about 92.3 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 42m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 97.8 miles or 2h 5m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 24m

Traffic, exits, and arrival timing usually matter more near Saltillo, MS than in the middle of the route.

Before You Leave

Open the route before leaving Greenville, MS so your first major turns are already loaded.

Leave with enough water and a charging cable within reach, not packed away.

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Greenville, MS

This is one driving day of about 195.7 miles and 4h 10m.

Your first comfortable stop window is around 80 miles from Greenville, MS.

This route can stay practical as a one-day drive if traffic stays reasonable.

Plan about 1 real break rather than only quick fuel stops.

The longest stretch is on US 278 for about 92.3 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 97.8 mi from Greenville, MS · 2h 5m into the drive

Mid-route town

Meal stop

Memphis, TN

98 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Memphis, TN

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Memphis, TN

Meal break

The midpoint is around 97.8 miles from Greenville, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before US 278 if your tank is already low. That segment runs about 92.3 miles.

Arriving in Saltillo, MS

The final approach into Saltillo, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Saltillo, MS.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$29.92 one way

$59.83 round trip

$3.88/gal 25.4 MPG avg 69 kg CO₂

Fuel Type	$/gal	One Way	Round Trip
midgrade	$4.26	$32.81	$65.63
premium	$4.61	$35.52	$71.04
diesel	$5.64	$43.48	$86.96

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$30

Meals

$25–$50

Total

$55–$80

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 68.5 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $21 in charging · 0 stops · 66% less CO₂

Vehicle Type	kWh	DC Fast	Home Charge
Average EV	58.7	$20.55	$9.39
Efficient EV	48.9	$17.12	$7.83
EV Truck/SUV	78.3	$27.40	$12.52

Gas CO2

68 kg

EV CO2

23 kg (66% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 3 days ago

Origin

Greenville, MS

Late night in Greenville on Monday

Local time

5:18 AM

CDT

Current temp

67°F

Unavailable

Live forecast

Destination

Saltillo, MS

Late night in Saltillo on Monday

Local time

5:18 AM

CDT

Current temp

63°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

4 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 10m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Greenville, MS to Saltillo, MS covers 195.7 miles and takes about 4h 10m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are US 278, US 61, MS 9. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 97.8 miles from Greenville, MS. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $29.92 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

On the drive from Greenville, MS to Saltillo, MS, road signs begin pointing toward Sherman along the way.

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Trip from Greenville, MS to Saltillo, MS

Best Time to Leave

Trip Overview

Drive Character

How Hard Is This Drive?

Critical Maneuvers

Towns Along This Route

Main Roads

Turn-by-Turn Driving Directions

Trip Plan

Before You Leave

Where to Stop

Pacing Suggestions

Arriving in Saltillo, MS

Fuel & Cost

Travel Intel

Greenville, MS

Saltillo, MS

Same local time

4 degrees cooler at arrival

4h 10m on the road

Frequently Asked Questions

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