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Trip from Hattiesburg, MS to Saltillo, MS

Drive Time

4h 43m

Distance

240.4 mi

387 km

Drive Score

10/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$37

one way

EV Charging

Loading...

station data

Best Time to Leave

Save up to 40 min
4 AM
4h 30m ★
6 AM
4h 43m
8 AM
5h 10m
10 AM
4h 53m
12 PM
4h 50m
3 PM
4h 54m
5 PM
5h 9m
8 PM
4h 35m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly
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Downtown Saltillo, MS, MS

Saltillo, MS

Wikimedia Commons

Trip Overview

The drive from Hattiesburg, MS to Saltillo, MS covers 240.4 miles and takes about 4h 43m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Lance Corporal Roy M Wheat Memorial Highway, US 45, US Highway 45 Alternate for much of the mileage, and the overall profile is mixed drive. The longest uninterrupted segment is about 77.7 miles on Lance Corporal Roy M Wheat Memorial Highway. At current regular gas prices, budget about $36.75 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

120.2 miles from Hattiesburg, MS

A natural place for your longest stop of the day , about 2h 17m into the drive .

Drive Character

The drive from Hattiesburg, MS to Saltillo, MS covers 240.4 miles and takes about 4h 43m, using a mix of highways and local roads.

Expect a mix of faster highway mileage and slower local approaches near the beginning or end.
There are about 24 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Lance Corporal Roy M Wheat Memorial Highway is the longest continuous segment at about 77.7 miles.

How Hard Is This Drive?

This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes early in the drive near MS 967 / North Main Street.

Route Complexity 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

This is a demanding drive. With 15 significant decision points across 240.4 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: near the start (MS 967 / North Main Street): Lane positioning matters here; at 1.3 miles (Old Highway 42): Lane positioning matters here; at 3 miles (MS 42 / Evelyn Gandy Parkway): Lane positioning matters here.

Critical Maneuvers

5 of 15 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6
0 mi into trip | ~0m in | MS 967 / North Main Street

Turn right onto MS 967 / North Main Street

Lane positioning matters here

Use the straight / right lanes.
6
1.3 mi into trip | ~3m in | Old Highway 42

At end of road, turn left onto Old Highway 42

Lane positioning matters here

Use the straight lane.
6
3 mi into trip | ~7m in | MS 42 / Evelyn Gandy Parkway

Turn left onto MS 42 / Evelyn Gandy Parkway

Lane positioning matters here

Use the straight lane.
8
82.9 mi into trip | ~1h 34m in | I 59

Keep slight right at fork onto I 59 toward I 59 North, I 20 East: Meridian, Tuscaloosa

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight lane. Toward I 59 North, I 20 East: Meridian, Tuscalo...
8
157.3 mi into trip | ~3h in | US 45 ALT / US Highway 45 Alternate

Keep slight left at fork onto US 45 ALT / US Highway 45 Alternate toward US 45 Alternate North: West Point, Tupelo

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight left lanes. Toward US 45 Alternate North: West Point, Tupel...

Towns Along This Route

Between Hattiesburg, MS and Saltillo, MS, road signs point toward Tuscaloosa and Tupelo.

Tuscaloosa

82.9 mi in | ~1h 34m | via I 59

Tupelo

157.3 mi in | ~3h | via US 45 ALT

Main Roads

Road Distance Duration
Lance Corporal Roy M Wheat Memorial Highway 77.7 mi 1h 24m
US 45 72.2 mi 1h 22m
US Highway 45 Alternate 53 mi 1h 3m
Martin Luther King Drive 18.1 mi 20m
I 59 9 mi 10m
Martin Luther King, Junior Drive 3.3 mi 4m
Evelyn Gandy Parkway 1.9 mi 2m
North Main Street 1.3 mi 3m
Longest stretch: Lance Corporal Roy M Wheat Memorial Highway — 77.7 mi, about 1h 24m

Turn-by-Turn Driving Directions

Step-by-step road directions between Hattiesburg, MS and Saltillo, MS.

1

Start on East Pine Street

26 ft · 5 sec · East Pine Street
2

Turn right onto North Main Street

1.3 mi · 3 min · North Main Street
3

At the end of the road, turn left onto Old Highway 42

0.2 mi · 29 sec · Old Highway 42
4

Turn right onto Glendale Avenue

1.3 mi · 3 min · Glendale Avenue
5

Keep slight right to continue on Monroe Road

0.2 mi · 28 sec · Monroe Road
6

Turn left onto Evelyn Gandy Parkway

1.9 mi · 2 min · Evelyn Gandy Parkway
7

Take the ramp slight right

0.3 mi · 42 sec
8

Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway

78 mi · 1 hr 24 min · Lance Corporal Roy M Wheat Memorial Highway
9

Keep slight right to continue on I 59 North, I 20 East: Meridian, Tuscaloosa

9.0 mi · 10 min · I 59 North, I 20 East: Meridian, Tuscaloosa
10

Take the exit slight right toward US 45 North: Macon

0.3 mi · 47 sec · US 45 North: Macon
11

Merge slight left

65 mi · 1 hr 14 min
12

Keep slight left to continue on US Highway 45 Alternate

53 mi · 1 hr 4 min · US Highway 45 Alternate
13

Continue on Martin Luther King Drive

18 mi · 20 min · Martin Luther King Drive
14

Continue on Martin Luther King, Junior Drive

3.3 mi · 4 min · Martin Luther King, Junior Drive
15

Keep slight right

7.1 mi · 8 min
16

Take the exit slight right

0.3 mi · 45 sec
17

Keep slight right

341 ft · 8 sec
18

Turn straight

0.2 mi · 22 sec
19

Turn slight right

453 ft · 20 sec
20

Continue straight

377 ft · 20 sec
21

Turn left onto Kyle Avenue

0.3 mi · 1 min · Kyle Avenue
22

At the end of the road, turn left

0.5 mi · 2 min
23

Continue on East Mobile Street

502 ft · 10 sec · East Mobile Street
24

Arrive at your destination

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 120.2 miles from Hattiesburg, MS, or about 2h 17m into the drive.
The longest continuous stretch on this route runs about 77.7 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 31m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 120.2 miles or 2h 17m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 48m

Traffic, exits, and arrival timing usually matter more near Saltillo, MS than in the middle of the route.

Before You Leave

+

Open the route before leaving Hattiesburg, MS so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Hattiesburg, MS

This is one driving day of about 240.4 miles and 4h 43m.

Your first comfortable stop window is around 80 miles from Hattiesburg, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Lance Corporal Roy M Wheat Memorial Highway for about 77.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 120.2 mi from Hattiesburg, MS · 2h 17m into the drive

Downtown Butler, AL, AL

Mid-route town

Meal stop

Butler, AL

120 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Butler, AL

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Butler, AL

Meal break

The midpoint is around 120.2 miles from Hattiesburg, MS, which is a good place for a longer meal and fuel stop.

Arriving in Saltillo, MS

The final approach into Saltillo, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Saltillo, MS.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

National Parks Near This Route

Worth a detour if your schedule allows.

Tupelo National Battlefield

Tupelo National Battlefield

National Battlefield

In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...

2 mi from route ~6 min detour Free near mile 232.1
View on nps.gov
Natchez Trace National Scenic Trail

Natchez Trace National Scenic Trail

National Scenic Trail

The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...

3 mi from route ~9 min detour Free near mile 232.1
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

Fuel & Cost

Regular Gas

$36.75 one way

$73.50 round trip

$3.88/gal 25.4 MPG avg 84 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.26 $40.31 $80.62
premium $4.61 $43.63 $87.26
diesel $5.64 $53.41 $106.82

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$37

Meals

$25–$50

Total

$62–$87

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 84.1 kg one way. Prices: EIA weekly data, 2026-04-06.

Driving Electric?

About $25 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 72.1 0 $25.24 $11.54
Efficient EV 60.1 0 $21.04 $9.62
EV Truck/SUV 96.2 1 $33.66 $15.39

Gas CO2

84 kg

EV CO2

28 kg (67% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast data refreshed 3 days ago

Origin

Hattiesburg, MS

Late night in Hattiesburg on Monday

Local time

4:00 AM

CDT

Current temp

64°F

Unavailable

Live forecast

Destination

Saltillo, MS

Late night in Saltillo on Monday

Local time

4:00 AM

CDT

Current temp

63°F

Unavailable

Live forecast

Along the Route

86°F

Butler, AL

120 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

1 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 43m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Hattiesburg, MS to Saltillo, MS covers 240.4 miles and takes about 4h 43m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Lance Corporal Roy M Wheat Memorial Highway, US 45, US Highway 45 Alternate. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 120.2 miles from Hattiesburg, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $36.75 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 15 significant decision points across 240.4 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: near the start (MS 967 / North Main Street): Lane positioning matters here; at 1.3 miles (Old Highway 42): Lane positioning matters here; at 3 miles (MS 42 / Evelyn Gandy Parkway): Lane positioning matters here.
Between Hattiesburg, MS and Saltillo, MS, road signs point toward Tuscaloosa and Tupelo.

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