Drive Time
1h 53m
Distance
117 mi
188 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$18
one way
Photo: Amicia Short
Connecting Hannibal to St. Louis is a straightforward 117-mile journey that typically takes about 1 hour and 53 minutes. Because of the relatively short distance, this trip is perfectly manageable as a simple one-day excursion, meaning you won't need to worry about booking an overnight stay. You can expect to spend approximately $17 on fuel for the trip, making it a budget-friendly way to move between these two Missouri cities. Since both locations are situated within the Midwest, the drive keeps you firmly rooted in the region's landscape. If you prefer a relaxed pace without the pressure of an interstate trek, this local route offers a direct, no-fuss path to your destination.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
0 planned breaks
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
58.5 miles from Hannibal, MO
A natural place for your longest stop of the day , about 56m into the drive .
Expect a turn-heavy local drive rather than a monotonous highway cruise, as this route features zero highway miles. You will navigate via Broadway, Grand Avenue, and Warren Barett Drive, which keeps you off the major interstates entirely. Because there is no single long-distance stretch on Broadway, you will be making frequent adjustments behind the wheel throughout the entire 117-mile duration. This creates a more engaged driving experience that demands your attention on local roads. The lack of highway share ensures you see the landscape from a different perspective than you would on a standard freeway, though it does mean the pace is dictated by local traffic patterns.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. Navigation is very simple — set it and forget it for most of the drive.
Very easy - short and simple to drive
The drive from Hannibal, MO to St. Louis, MO is easy. At 1h 53m with 0% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Hannibal, MO to St. Louis, MO is straightforward, with well-signed roads and simple exits.
| Road | Distance | Duration |
|---|---|---|
| Broadway | Unavailable | Refreshing |
| Grand Avenue | Unavailable | Refreshing |
| Warren Barett Drive | Unavailable | Refreshing |
| Avenue of the Saints | Unavailable | Refreshing |
| Daniel Boone Expressway | Unavailable | Refreshing |
| Jack Buck Memorial Highway | Unavailable | Refreshing |
| 14th Street | Unavailable | Refreshing |
| South 14th Street | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Step-by-step road directions between Hannibal, MO and St. Louis, MO.
Start on the route
Turn left onto Broadway
Turn left onto Grand Avenue
Turn right onto Warren Barett Drive
Turn left onto Avenue of the Saints
Continue on Daniel Boone Expressway
Continue on Jack Buck Memorial Highway
Take the exit slight right toward 14th Street
Turn left onto South 14th Street
Turn right onto Market Street
Arrive at your destination
Since this is a sub-two-hour drive, you have plenty of flexibility to plan your departure time around your personal schedule rather than rushing to beat traffic. With no mandatory stops required to cover the 117 miles, you can complete the trip in one sitting, though building in a quick break can help you stay refreshed for the more technical, turn-heavy sections. Keep an eye on your fuel gauge before you head out, as the $17 estimated cost can fluctuate based on your vehicle's efficiency on local roads. My best advice is to familiarize yourself with the specific turns on Grand Avenue and Warren Barett Drive before you pull out of Hannibal. By staying mindful of your navigation, you can enjoy a smooth, efficient trip into St. Louis.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 17m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 58.5 miles or 56m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 32m
Traffic, exits, and arrival timing usually matter more near St. Louis, MO than in the middle of the route.
Open the route before leaving Hannibal, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Hannibal, MO
This is one driving day of about 117 miles and 1h 53m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 58.5 mi from Hannibal, MO · 56m into the drive
Mid-route town
Meal stop
59 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 58.5 miles from Hannibal, MO, which is a good place for a longer meal and fuel stop.
The final approach into St. Louis, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around St. Louis, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$17.77 one way
$35.54 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $19.59 | $39.18 |
| premium | $4.80 | $22.09 | $44.17 |
| diesel | $5.64 | $25.99 | $51.99 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$18
Meals
$25–$50
Total
$43–$68
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 40.9 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $12 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 35.1 | 0 | $12.29 | $5.62 |
| Efficient EV | 29.3 | 0 | $10.24 | $4.68 |
| EV Truck/SUV | 46.8 | 0 | $16.38 | $7.49 |
Gas CO2
41 kg
EV CO2
14 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Hannibal on Sunday
Local time
1:13 AM
CDT
Current temp
55°F
Forecast unavailable right now
Destination
Late night in St. Louis on Sunday
Local time
1:13 AM
CDT
Current temp
59°F
Forecast unavailable right now
Along the Route
57°F
Alton, IL
59 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
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