The drive from Harlem, FL to Fleming Island, FL covers 295.6 miles and takes about 6h 4m behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Florida's Turnpike, I 95, I 4 for much of the mileage,
and the overall profile is highway-focused drive.
The longest uninterrupted segment is about 65.6 miles on Florida's Turnpike.
At current regular gas prices, budget about $47.05 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
147.8 miles from Harlem, FL
A natural place for your longest stop of the day
, about 3h 5m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 4m. Total distance: 295.6 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 4m drive, plan rest stops for pacing.
Drive Character
This is a 6h 4m highway drive covering 295.6 miles, with most of the trip on Florida's Turnpike and I 95. The longest continuous stretch is about 65.6 miles on Florida's Turnpike.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 43 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Florida's Turnpike is the longest continuous segment at about 65.6 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on Florida's Turnpike and I 95. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 88 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 26 significant decision points across 295.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 88 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 88.2 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 154.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 26 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
6
88 mi into trip|~2h in
Take the exit
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the left lane.
7
88.2 mi into trip|~2h 1m in
Keep slight left at fork toward Florida's Turnpike North: Orlando
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward Florida's Turnpike North: Orlando
8
154.2 mi into trip|~3h 12m in
Take the exit toward I 4: Orlando, Tampa
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 259
Toward I 4: Orlando, Tampa
6
209.7 mi into trip|~4h 16m in
Keep slight left at fork toward I 95: Miami, Jacksonville
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 95: Miami, Jacksonville
7
211.2 mi into trip|~4h 18m in
Keep slight left at fork toward I 95 North: Jacksonville
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward I 95 North: Jacksonville
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Harlem, FL and Fleming Island, FL, road signs point toward Florida's Turnpike North: Orlando, Tampa, Jacksonville and Green Cove Springs.
Florida's Turnpike North: Orlando
88.2 mi in|~2h 1m
Tampa
154.2 mi in|~3h 12m
Jacksonville
209.7 mi in|~4h 16m
Green Cove Springs
266.9 mi in|~5h 19m
Main Roads
Road
Distance
Duration
Florida's Turnpike
65.6 mi
1h 10m
I 95
54.8 mi
59m
I 4
54.7 mi
1h 2m
Industrial Drive
34.4 mi
46m
US 441
31.8 mi
40m
US 27
15.3 mi
19m
FL 16
12.2 mi
17m
Orange Avenue
6.2 mi
10m
Longest stretch:
Florida's Turnpike
— 65.6 mi, about 1h 10m
Turn-by-Turn Driving Directions
Step-by-step road directions between Harlem, FL and Fleming Island, FL.
1
Start on 10th Street
89 ft·5 sec·10th Street
2
Turn right onto Harlem Academy Avenue
0.5 mi·1 min·Harlem Academy Avenue
3
At end of road, turn right onto 13th Street
0.1 mi·22 sec·13th Street
4
At end of road, turn left onto Lewis Boulevard
1.1 mi·2 min·Lewis Boulevard
5
Take the ramp
0.1 mi·22 sec
6
Merge onto US 27; FL 80
4.9 mi·5 min·US 27; FL 80
7
Continue on US 27; FL 80
10 mi·14 min·US 27; FL 80
Use the left lane.
8
Turn right onto FL 78 Detour
34 mi·46 min·Industrial Drive
9
Turn left onto Parrott Avenue
4.3 mi·8 min·Parrott Avenue
10
Continue on US 441
0.6 mi·1 min·US 441
11
Continue on US 441
31 mi·39 min·US 441
12
Turn sharp right onto FL 60
0.4 mi·49 sec·FL 60
Use the left lane.
13
Take the exit
0.1 mi·19 sec
Use the left lane.
14
Continue on this road
295 ft·7 sec·this road
Use the straight / slight right lanes.
15
Keep slight left at fork
0.4 mi·57 sec
Toward Florida's Turnpike North: OrlandoUse the straight / slight right lanes.
16
Merge onto Florida's Turnpike
66 mi·1 hr 10 min·Florida's Turnpike
Use the straight lane.
17
Take the exit
0.4 mi·54 sec
Exit 259Toward I 4: Orlando, TampaUse the straight / slight right lanes.
18
Keep slight right at fork
0.3 mi·38 sec
Toward I 4 East: Downtown Orlando
19
Merge onto I 4
55 mi·1 hr 2 min·I 4
Use the straight / slight right lanes.
20
Keep slight left at fork
0.2 mi·14 sec
Toward I 95: Miami, Jacksonville
21
Keep slight left at fork
1.2 mi·2 min
Toward I 95 North, US 92 North: Jacksonville
22
Keep slight left at fork
1.0 mi·1 min
Toward I 95 North: JacksonvilleUse the straight / slight right lanes.
23
Merge onto I 95
55 mi·59 min·I 95
Use the straight / slight right lanes.
24
Take the exit
0.3 mi·42 sec
Exit 318Toward FL 16: Saint Augustine, Green Cove Springs
25
Merge onto FL 16
319 ft·6 sec·Charles Usinas Memorial Highway
26
Continue on FL 16
2.0 mi·3 min·Pensacola-St. Augustine Highway
Use the left / straight lanes.
27
Continue on FL 16
5.2 mi·7 min·FL 16
Use the straight lane.
28
Turn straight onto CR 16A
0.2 mi·18 sec·CR 16A
29
Turn left onto Silverleaf Parkway
106 ft·4 sec·Silverleaf Parkway
30
Continue on FL 16
1.7 mi·2 min·FL 16
31
At end of road, turn right onto FL 13; FL 16
4.0 mi·5 min·FL 13; FL 16
32
Turn slight left onto FL 16
0.3 mi·28 sec·FL 16
33
At end of road, turn left onto FL 16
5.1 mi·7 min·FL 16
34
Turn right onto US 17; FL 16
6.2 mi·10 min·Orange Avenue
Use the left lane.
35
Continue on US 17
394 ft·6 sec·US 17
36
Continue on US 17
2.2 mi·3 min·US 17
37
Turn left onto East West Parkway
0.4 mi·1 min·East West Parkway
38
Turn left onto Town Center Boulevard
0.5 mi·1 min·Town Center Boulevard
39
Enter roundabout
22 ft·0 sec
40
Continue
54 ft·2 sec
41
Continue on Radar Road
0.3 mi·1 min·Radar Road
42
Turn right
0.1 mi·40 sec
43
Arrive at destination
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 147.8 miles from Harlem, FL, or about 3h 5m into the drive.
The longest continuous stretch on this route runs about 65.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 65 miles or 1h 31m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 147.8 miles or 3h 5m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 52m
Traffic, exits, and arrival timing usually matter more near Fleming Island, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Harlem, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Harlem, FL
This is one driving day of about 295.6 miles and 6h 4m.
Your first comfortable stop window is around 65 miles from Harlem, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Florida's Turnpike for about 65.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 147.8 mi from Harlem, FL
· 3h 5m into the drive
The midpoint is around 147.8 miles from Harlem, FL, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before Florida's Turnpike if your tank is already low. That segment runs about 65.6 miles.
Arriving in Fleming Island, FL
The final approach into Fleming Island, FL usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Fleming Island, FL.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
National Parks Near This Route
Worth a detour if your schedule allows.
Castillo de San Marcos National Monument
National Monument
Built by the Spanish in St. Augustine to defend Florida and the Atlantic trade route, Castillo de San Marcos National Monument preserves the oldest masonry fortification in the continental United Stat...
5 mi from route
~14 min detour
$15
near mile 265.1
Fort Matanzas National Monument preserves the fortified coquina watchtower, completed in 1742, which defended the southern approach to the Spanish military settlement of St. Augustine. It also protect...
6 mi from route
~16 min detour
Free
near mile 244.7
Park data from the National Park Service API. Alerts update every 2 hours.
Fuel & Cost
Regular Gas
$47.05 one way
$94.10 round trip
$4.04/gal25.4 MPG avg103 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.40
$51.18
$102.37
premium
$4.72
$54.97
$109.93
diesel
$5.61
$65.26
$130.53
Estimated Tolls: $4.59
Florida's Turnpike
(65.6 mi)$4.59
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$47
Tolls
$5
Meals
$25–$50
Total
$77–$102
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 103.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $31 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
88.7
1
$31.04
$14.19
Efficient EV
73.9
0
$25.87
$11.82
EV Truck/SUV
118.2
1
$41.38
$18.92
Gas CO2
103 kg
EV CO2
35 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Harlem, FL
Afternoon
in Harlem on Thursday
Local time
2:52 PM
EDT
Current temp
79°F
Unavailable
Live forecast
Destination
Fleming Island, FL
Afternoon
in Fleming Island on Thursday
Local time
2:52 PM
EDT
Current temp
80°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 4m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Harlem, FL to Fleming Island, FL covers 295.6 miles and takes about 6h 4m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Florida's Turnpike, I 95, I 4. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 147.8 miles from Harlem, FL. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $47.05 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 26 significant decision points across 295.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 88 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 88.2 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 154.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Harlem, FL and Fleming Island, FL, road signs point toward Florida's Turnpike North: Orlando, Tampa, Jacksonville and Green Cove Springs.
Yes. Nearby national parks include Castillo de San Marcos National Monument and Fort Matanzas National Monument.
