Spanning 241.6 miles across Missouri, this route from Independence to Byrnes Mill is a manageable journey that typically takes about 4 hours and 46 minutes behind the wheel. Because the total drive time is under five hours, you can comfortably tackle this as a single-day trip without needing an overnight stop. You will navigate via the Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, and the Avenue of the Saints. Expect to budget approximately $37 for fuel, making this an economical choice for a weekend getaway or a necessary commute. Since both your starting point and destination are located in the Midwest, you will experience consistent regional surroundings throughout the duration of your trip.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
120.8 miles from Independence, MO
A natural place for your longest stop of the day
, about 2h 14m into the drive
.