Origin
Isle of Palms, SC
Afternoon in Isle of Palms on Sunday
Local time
12:36 PM
EDT
Current temp
64°F
Unavailable
Live forecast
Trip from Isle of Palms, SC to Anderson County Airport, SC
Drive Time
4h 45m
Distance
240.1 mi
386 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$38
one way
Photo: Jaxon Matthew Willis
Trip Overview
The drive from Isle of Palms, SC to Anderson County Airport, SC covers 240.1 miles and takes about 4h 45m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on I 26, I 385, Mark Clark Expressway for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 158.7 miles on I 26. At current regular gas prices, budget about $38.43 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
120 miles from Isle of Palms, SC
A natural place for your longest stop of the day , about 2h 18m into the drive .
Drive Character
This is a 4h 45m highway drive covering 240.1 miles, with most of the trip on I 26 and I 385. The longest continuous stretch is about 158.7 miles on I 26.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 34 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 26 is the longest continuous segment at about 158.7 miles.
How Hard Is This Drive?
This is a straightforward highway drive that stays mostly on I 26 and I 385. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 4 miles in near Hungry Neck Boulevard.
Route Complexity
7/10
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 21 significant decision points across 240.1 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 4 miles (Hungry Neck Boulevard): Lane positioning matters here; at 6.2 miles (I 526 / Mark Clark Expressway): Merge point - match speed before joining. Lane positioning matters here; at 17.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 21 key pointsThese are the spots where you need to pay the most attention. Preview them before you drive.
6
4 mi into trip
|
~6m in
|
Hungry Neck Boulevard
Turn left onto Hungry Neck Boulevard
Lane positioning matters here
Use the straight lane.
5
6.2 mi into trip
|
~11m in
|
I 526 / Mark Clark Expressway
Merge onto I 526 / Mark Clark Expressway
Merge point - match speed before joining. Lane positioning matters here
Use the none lane.
8
17.1 mi into trip
|
~24m in
Take the exit toward US 52 West, US 78 West: Rivers Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 18B
Toward US 52 West, US 78 West: Rivers Avenue
5
19.1 mi into trip
|
~27m in
|
I 26
Merge onto I 26
Merge point - match speed before joining. Lane positioning matters here
Use the none / straight / slight right lanes.
9
177.8 mi into trip
|
~3h 21m in
|
I 385
Keep slight left at fork onto I 385 toward I 385 North: Laurens, Greenville
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / straight lanes.
Exit 51
Toward I 385 North: Laurens, Greenville
Towns Along This Route
Between Isle of Palms, SC and Anderson County Airport, SC, road signs point toward Greenville and Pelzer.
Greenville
177.8 mi in
|
~3h 21m
|
via I 385
Pelzer
200.7 mi in
|
~3h 45m
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 26 | 158.7 mi | 2h 53m |
| I 385 | 22.9 mi | 24m |
| Mark Clark Expressway | 11 mi | 13m |
| Highway 418 | 9.9 mi | 14m |
| Cooley Bridge Road | 5.6 mi | 8m |
| Belton Highway | 4.7 mi | 6m |
| Isle of Palms Connector | 3.6 mi | 6m |
| Highway 247 | 3.6 mi | 4m |
Longest stretch:
I 26
— 158.7 mi, about 2h 53m
Turn-by-Turn Driving Directions
Step-by-step road directions between Isle of Palms, SC and Anderson County Airport, SC.
1
Start on SC 703
0.4 mi
·
53 sec
·
Palm Boulevard
Use the none lane.
2
Turn left onto Isle of Palms Connector
3.6 mi
·
6 min
·
Isle of Palms Connector
Use the left / none lanes.
3
Turn left onto Hungry Neck Boulevard
1.3 mi
·
2 min
·
Hungry Neck Boulevard
Use the straight lane.
4
Keep slight left at fork
0.8 mi
·
1 min
5
Merge onto I 526
11 mi
·
13 min
·
Mark Clark Expressway
Use the none lane.
6
Take the exit
0.2 mi
·
31 sec
Exit 18B
Toward US 52 West, US 78 West: Rivers Avenue
Use the slight right lane.
7
Turn slight right onto US 52; US 78
1.1 mi
·
1 min
·
Rivers Avenue
Use the straight lane.
8
Turn straight
0.1 mi
·
20 sec
9
Take the ramp
0.5 mi
·
45 sec
Toward I 26 North: Columbia
10
Merge onto I 26
159 mi
·
2 hr 53 min
·
I 26
Use the none / straight / slight right lanes.
11
Keep slight left at fork onto I 385
23 mi
·
24 min
·
I 385
Exit 51
Toward I 385 North: Laurens, Greenville
Use the slight left / straight lanes.
12
Take the exit
0.2 mi
·
37 sec
Toward SC 418: Fountain Inn, Pelzer
13
Turn left onto SC 418
0.4 mi
·
42 sec
·
McCarter Road
14
Continue on SC 418
1.3 mi
·
2 min
·
Milacron Drive
15
Continue on SC 418
9.9 mi
·
14 min
·
Highway 418
16
Turn left onto US 25
0.1 mi
·
11 sec
·
Augusta Road
17
Turn right onto SC 247
5.6 mi
·
8 min
·
Cooley Bridge Road
18
Continue on SC 247
3.6 mi
·
4 min
·
Highway 247
19
Continue on SC 247
1.3 mi
·
2 min
·
River Street
20
Turn left onto SC 20
374 ft
·
12 sec
·
North Main Street
21
Turn right onto US 76; US 178; SC 20
2.3 mi
·
3 min
·
Anderson Street
22
Continue on US 76; US 178
4.7 mi
·
6 min
·
Belton Highway
23
Continue on US 76; US 178
2.6 mi
·
3 min
·
East River Street
24
Turn left onto US 29
2.0 mi
·
2 min
·
East Shockley Ferry Road
25
At end of road, turn left onto US 29
468 ft
·
10 sec
·
South Murray Avenue
26
Turn right onto SC 28
0.5 mi
·
34 sec
·
Pearman Dairy Road
27
Continue on SC 28
2.2 mi
·
2 min
·
Highway 28 Bypass
28
Turn left onto SC 24
1.0 mi
·
1 min
·
West Whitner Street
29
Continue on SC 24
0.7 mi
·
1 min
·
Highway 24
30
Turn left onto Airport Road
0.4 mi
·
59 sec
·
Airport Road
31
Continue on South Warner Road
0.4 mi
·
58 sec
·
South Warner Road
32
Turn sharp left onto Airport Road
55 ft
·
7 sec
·
Airport Road
33
Turn right
293 ft
·
21 sec
34
Arrive at destination
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 120 miles from Isle of Palms, SC, or about 2h 18m into the drive.
The longest continuous stretch on this route runs about 158.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 120 miles or 2h 18m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 41m
Traffic, exits, and arrival timing usually matter more near Anderson County Airport, SC than in the middle of the route.
Before You Leave
+
Open the route before leaving Isle of Palms, SC so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Isle of Palms, SC
This is one driving day of about 240.1 miles and 4h 45m.
Your first comfortable stop window is around 80 miles from Isle of Palms, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 26 for about 158.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 120 mi from Isle of Palms, SC · 2h 18m into the drive
Mid-route town
Meal stop
120 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 80 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 120 miles from Isle of Palms, SC, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 26 if your tank is already low. That segment runs about 158.7 miles.
Arriving in Anderson County Airport, SC
The final approach into Anderson County Airport, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Anderson County Airport, SC.
After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$38.43 one way
$76.85 round trip
$4.07/gal
25.4 MPG avg
84 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.43 | $41.87 | $83.73 |
| premium | $4.78 | $45.17 | $90.33 |
| diesel | $5.64 | $53.34 | $106.68 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$38
Meals
$25–$50
Total
$63–$88
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 84 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $25 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 72 | 0 | $25.21 | $11.52 |
| Efficient EV | 60 | 0 | $21.01 | $9.60 |
| EV Truck/SUV | 96 | 1 | $33.61 | $15.37 |
Gas CO2
84 kg
EV CO2
28 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Anderson County Airport, SC
Afternoon in Anderson County Airport on Sunday
Local time
12:36 PM
EDT
Current temp
63°F
Unavailable
Live forecast
Along the Route
62°F
Inman Mills, SC
120 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 45m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Isle of Palms, SC to Anderson County Airport, SC covers 240.1 miles and takes about 4h 45m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 26, I 385, Mark Clark Expressway. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 120 miles from Isle of Palms, SC. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $38.43 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 21 significant decision points across 240.1 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 4 miles (Hungry Neck Boulevard): Lane positioning matters here; at 6.2 miles (I 526 / Mark Clark Expressway): Merge point - match speed before joining. Lane positioning matters here; at 17.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Between Isle of Palms, SC and Anderson County Airport, SC, road signs point toward Greenville and Pelzer.
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Return Trip
Anderson County Airport, SC to Isle of Palms, SCPlan the drive back the other way.
240.1 mi
4h 46m
Continue From Anderson County Airport, SC
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