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Trip from Itawamba County, MS to Meridian, MS

Last recalculated Apr 16, 2026

Drive Time

3h 20m

Distance

164.1 mi

264 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$25

one way

EV Charging

Unknown

Best Time to Leave

Save up to 36 min
4 AM
3h 9m ★
6 AM
3h 21m
8 AM
3h 45m
10 AM
3h 29m
12 PM
3h 27m
3 PM
3h 30m
5 PM
3h 43m
8 PM
3h 13m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Itawamba County, MS, MS

Itawamba County, MS

Mark Stebnicki

Downtown Meridian, MS, MS

Meridian, MS

Wikimedia Commons

Trip Overview

The drive from Itawamba County, MS to Meridian, MS covers 164.1 miles and takes about 3h 20m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on US Highway 45 Aiternate, US Highway 45 Alternate, I 22 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 60.6 miles on US Highway 45 Aiternate. At current regular gas prices, budget about $24.78 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

82.1 miles from Itawamba County, MS

A natural place for your longest stop of the day , about 1h 42m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 3h 20m. Total distance: 164.1 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

3h 20m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (88%). Some complex stretches to watch for.

Drive Character

This is a 3h 20m highway drive covering 164.1 miles, with most of the trip on US Highway 45 Aiternate and US Highway 45 Alternate. The longest continuous stretch is about 60.6 miles on US Highway 45 Aiternate.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 29 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US Highway 45 Aiternate is the longest continuous segment at about 60.6 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on US Highway 45 Aiternate and US Highway 45 Alternate. You will hit about 13 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.2 miles in near MS 178.

Driving Effort 6/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 164.1 miles you will encounter 13 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 0.2 miles (MS 178): Navigation decision point; at 2.5 miles (South Adams Street): Lane positioning matters here; at 19.3 miles: Highway fork - watch signs carefully.

Critical Maneuvers

5 of 13 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

4
0.2 mi into trip | ~0m in | MS 178

Turn right onto MS 178

Navigation decision point

5
2.5 mi into trip | ~4m in | South Adams Street

Turn left onto South Adams Street

Lane positioning matters here

Use the left lane.
5
19.3 mi into trip | ~24m in

Keep slight left at fork

Highway fork - watch signs carefully

7
24.8 mi into trip | ~34m in

Turn left toward US 45 South, MS 6 West: Columbus, Pontotoc

Lane positioning matters here. Multiple destination signs - pick the right one

Use the left lane. Toward US 45 South, MS 6 West: Columbus, Pontot...
5
164.1 mi into trip | ~3h 20m in | 25th Avenue

Turn left onto 25th Avenue

Navigation decision point

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from Itawamba County, MS to Meridian, MS, road signs begin pointing toward Pontotoc along the way.

Pontotoc

24.8 mi in | ~34m

Main Roads

Road Distance Duration
US Highway 45 Aiternate 60.6 mi 1h 9m
US Highway 45 Alternate 54.7 mi 1h 6m
I 22 14.2 mi 15m
Martin Luther King Drive 7.7 mi 8m
US 45 ALT 7.2 mi 8m
North Eason Boulevard 5.1 mi 8m
Old Highway 45 North 4.8 mi 7m
MS 178 2.4 mi 4m
Longest stretch: US Highway 45 Aiternate — 60.6 mi, about 1h 9m

Turn-by-Turn Driving Directions

Step-by-step road directions between Itawamba County, MS and Meridian, MS.

1

Start on Walton Road Southwest

0.2 mi · 37 sec · Walton Road Southwest
2

Turn right onto MS 178

2.4 mi · 4 min · MS 178
3

Turn left onto South Adams Street

2.0 mi · 3 min · South Adams Street
Use the left lane.
4

Take the ramp

0.4 mi · 45 sec
Toward Tupelo
5

Merge onto I 22; US 78

14 mi · 15 min · I 22; US 78
6

Take the exit

0.2 mi · 27 sec
Toward Auburn Road
7

Keep slight left at fork

182 ft · 6 sec
8

Turn left

115 ft · 2 sec
9

Turn straight onto CR 931

0.4 mi · 54 sec · Auburn Road
10

Continue on North Eason Boulevard

5.1 mi · 8 min · North Eason Boulevard
Use the straight lane.
11

Turn left

0.3 mi · 33 sec
Toward US 45 South, MS 6 West: Columbus, Pontotoc Use the left lane.
12

Merge onto US 45; MS 6

1.9 mi · 2 min · Martin Luther King, Junior Drive
13

Continue on US 45; US 278

7.7 mi · 8 min · Martin Luther King Drive
14

Continue on US 45 ALT

1.4 mi · 1 min · US 45 ALT
15

Continue on US 45 ALT

2.2 mi · 2 min · US 45 ALT
16

Continue on US 45 ALT

1.5 mi · 1 min · US 45 ALT
17

Continue on US 45 ALT

0.7 mi · 49 sec · US 45 ALT
18

Continue on US 45 ALT

1.4 mi · 1 min · US 45 ALT
19

Continue on US 45 ALT

55 mi · 1 hr 6 min · US Highway 45 Alternate
Use the straight lane.
20

Continue on US 45

61 mi · 1 hr 9 min · US Highway 45 Aiternate
21

Keep slight left at fork onto Old Highway 45 North

4.8 mi · 7 min · Old Highway 45 North
22

Continue on MS 884

0.6 mi · 54 sec · Dale Drive
23

Continue on Front Street

0.7 mi · 1 min · Front Street
24

Continue on 4th Street

0.1 mi · 9 sec · 4th Street
25

Turn slight left onto 2nd Street

0.5 mi · 49 sec · 2nd Street
26

Turn right onto 22nd Avenue

0.2 mi · 29 sec · 22nd Avenue
27

Turn left onto 8th Street

0.2 mi · 25 sec · 8th Street
28

Turn left onto 25th Avenue

272 ft · 11 sec · 25th Avenue
29

Arrive at destination

25th Avenue

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 82.1 miles from Itawamba County, MS, or about 1h 42m into the drive.
The longest continuous stretch on this route runs about 60.6 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 36 miles or 47m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 82.1 miles or 1h 42m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 43m

Traffic, exits, and arrival timing usually matter more near Meridian, MS than in the middle of the route.

Before You Leave

+

Open the route before leaving Itawamba County, MS so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Itawamba County, MS

This is one driving day of about 164.1 miles and 3h 20m.

Your first comfortable stop window is around 36 miles from Itawamba County, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US Highway 45 Aiternate for about 60.6 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 82.1 mi from Itawamba County, MS · 1h 42m into the drive

city in Mississippi, United States

Mid-route town

Meal stop

Starkville, MS

82 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Nettleton, MS

Fuel and coffee

A short stop after about 36 miles helps settle the day before fatigue starts building.

Macon, MS

Meal break

The midpoint is around 82.1 miles from Itawamba County, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before US Highway 45 Aiternate if your tank is already low. That segment runs about 60.6 miles.

Arriving in Meridian, MS

The final approach into Meridian, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Meridian, MS.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$24.78 one way

$49.57 round trip

$3.84/gal 25.4 MPG avg 57 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.21 $27.21 $54.41
premium $4.56 $29.45 $58.91
diesel $5.61 $36.23 $72.46

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$25

Meals

$25–$50

Total

$50–$75

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 57.4 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $17 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 49.2 0 $17.23 $7.88
Efficient EV 41 0 $14.36 $6.56
EV Truck/SUV 65.6 0 $22.97 $10.50

Gas CO2

57 kg

EV CO2

19 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 16, 2026

Origin

Itawamba County, MS

Afternoon in Itawamba County on Thursday

Local time

3:12 PM

CDT

Current temp

79°F

Unavailable

Live forecast

Destination

Meridian, MS

Afternoon in Meridian on Thursday

Local time

3:12 PM

CDT

Current temp

79°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

Very similar conditions

Both ends of the route are sitting at about the same temperature right now.

Road read

3h 20m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Itawamba County, MS to Meridian, MS covers 164.1 miles and takes about 3h 20m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are US Highway 45 Aiternate, US Highway 45 Alternate, I 22. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 82.1 miles from Itawamba County, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $24.78 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. A short stop every 2 to 3 hours is enough for this drive.
This drive requires moderate attention. Across 164.1 miles you will encounter 13 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
The main spots that need attention: at 0.2 miles (MS 178): Navigation decision point; at 2.5 miles (South Adams Street): Lane positioning matters here; at 19.3 miles: Highway fork - watch signs carefully.
On the drive from Itawamba County, MS to Meridian, MS, road signs begin pointing toward Pontotoc along the way.

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