The drive from La Monte, MO to St. Louis, MO covers 201.5 miles and takes about 4h behind the wheel.
This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Avenue of the Saints for much of the mileage,
and the overall profile is turn-heavy local drive.
The longest uninterrupted segment is about 82.8 miles on Dwight D. Eisenhower Highway.
At current regular gas prices, budget about $31.50 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
100.8 miles from La Monte, MO
A natural place for your longest stop of the day
, about 1h 58m into the drive
.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h. Total distance: 201.5 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h drive, comfortable solo distance.
Scenic Drive
Turn-heavy local drive route profile.
Drive Character
Expect a 4h drive with frequent turns across 201.5 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 24 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dwight D. Eisenhower Highway is the longest continuous segment at about 82.8 miles.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. You will hit about 14 points where you need to pay attention to lane position or signs. The trickiest moment comes around 1.2 miles in near Pleasant Green Road.
Driving Effort6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 201.5 miles you will encounter 14 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 1.2 miles (Pleasant Green Road): Navigation decision point; at 11.5 miles (US 65): Sharp turn - reduce speed on approach; at 161.4 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Critical Maneuvers
5 of 14 key points
These are the spots where you need to pay the most attention. Preview them before you drive.
5
1.2 mi into trip|~3m in|Pleasant Green Road
At end of road, turn right onto Pleasant Green Road
Navigation decision point
5
11.5 mi into trip|~17m in|US 65
Turn sharp left onto US 65
Sharp turn - reduce speed on approach
6
161.4 mi into trip|~3h 10m in|US 40
Take the exit onto US 40 toward I 64 East, US 40 East, US 61 South: Chesterfield
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 210A
Toward I 64 East, US 40 East, US 61 South: Ches...
5
161.7 mi into trip|~3h 10m in|I 64; US 40; US 61 / Avenue of the Saints
Merge onto I 64; US 40; US 61 / Avenue of the Saints
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight left lanes.
7
200.8 mi into trip|~3h 58m in
Take the exit toward 14th Street
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 39A
Toward 14th Street
Main Roads
Road
Distance
Duration
Dwight D. Eisenhower Highway
82.8 mi
1h 37m
U.S. Submarine Veterans' Memorial Highway
45.3 mi
48m
Avenue of the Saints
27.7 mi
33m
US 65
17.9 mi
21m
US 50
8.4 mi
10m
Jack Buck Memorial Highway
5.8 mi
7m
Daniel Boone Expressway
5.7 mi
7m
Sheriff Roger I. Wilson Memorial Highway
1.9 mi
2m
Longest stretch:
Dwight D. Eisenhower Highway
— 82.8 mi, about 1h 37m
Turn-by-Turn Driving Directions
Step-by-step road directions between La Monte, MO and St. Louis, MO.
1
Start on West Pine Street
219 ft·11 sec·West Pine Street
2
Turn right onto MO 127
0.7 mi·1 min·South Main Street
3
At end of road, turn left onto Front Street
0.4 mi·1 min·Front Street
4
At end of road, turn right onto Pleasant Green Road
95 ft·4 sec·Pleasant Green Road
5
Turn left onto US 50
8.4 mi·10 min·US 50
6
Turn left onto West Main Street
186 ft·7 sec·West Main Street
7
Continue on West Main Street
1.7 mi·3 min·West Main Street
8
Take the ramp
0.1 mi·27 sec
Toward US 65 South
9
Turn sharp left onto US 65
18 mi·21 min·US 65
10
Take the exit
0.4 mi·39 sec
Toward I 70 East: Saint Louis
11
Merge onto I 70; US 40
23 mi·24 min·U.S. Submarine Veterans' Memorial Highway
12
Keep slight left at fork onto I 70
22 mi·24 min·U.S. Submarine Veterans' Memorial Highway
13
Continue on I 70; US 40
1.8 mi·2 min·Dwight D. Eisenhower Highway
14
Continue on I 70; US 40
1.6 mi·1 min·Highway Patrol Sgt. Benjamin Booth Memorial Highway
15
Continue on I 70; US 40
1.9 mi·2 min·Sheriff Roger I. Wilson Memorial Highway
16
Continue on I 70; US 40
81 mi·1 hr 35 min·Dwight D. Eisenhower Highway
17
Take the exit onto US 40
0.3 mi·33 sec·US 40
Exit 210AToward I 64 East, US 40 East, US 61 South: Chesterfield
18
Merge onto I 64; US 40; US 61
28 mi·33 min·Avenue of the Saints
Use the straight / slight left lanes.
19
Continue on I 64; US 40
5.7 mi·7 min·Daniel Boone Expressway
Use the straight lane.
20
Continue on I 64; US 40
5.8 mi·7 min·Jack Buck Memorial Highway
Use the straight / slight right lanes.
21
Take the exit
0.2 mi·34 sec
Exit 39AToward 14th StreetUse the slight right lane.
22
Turn left onto South 14th Street
0.3 mi·42 sec·South 14th Street
Use the left lane.
23
Turn right onto Market Street
0.2 mi·25 sec·Market Street
24
Arrive at destination
Market Street
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 100.8 miles from La Monte, MO, or about 1h 58m into the drive.
The longest continuous stretch on this route runs about 82.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 44 miles or 54m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 100.8 miles or 1h 58m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 15m
Traffic, exits, and arrival timing usually matter more near St. Louis, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving La Monte, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from La Monte, MO
This is one driving day of about 201.5 miles and 4h.
Your first comfortable stop window is around 44 miles from La Monte, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Dwight D. Eisenhower Highway for about 82.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 100.8 mi from La Monte, MO
· 1h 58m into the drive
Place data sourced from public business listings. Hours and availability may vary.
Fuel & Cost
Regular Gas
$31.50 one way
$63.00 round trip
$3.97/gal25.4 MPG avg71 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$34.59
$69.18
premium
$4.89
$38.78
$77.55
diesel
$5.61
$44.49
$88.98
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$32
Meals
$25–$50
Total
$57–$82
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 70.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $21 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
60.4
0
$21.16
$9.67
Efficient EV
50.4
0
$17.63
$8.06
EV Truck/SUV
80.6
1
$28.21
$12.90
Gas CO2
71 kg
EV CO2
24 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
La Monte, MO
Morning
in La Monte on Friday
Local time
7:39 AM
CDT
Current temp
53°F
Unavailable
Live forecast
Destination
St. Louis, MO
Morning
in St. Louis on Friday
Local time
7:39 AM
CDT
Current temp
74°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
21 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from La Monte, MO to St. Louis, MO covers 201.5 miles and takes about 4h without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Dwight D. Eisenhower Highway, U.S. Submarine Veterans' Memorial Highway, Avenue of the Saints. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 100.8 miles from La Monte, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $31.50 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This drive requires moderate attention. Across 201.5 miles you will encounter 14 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
The main spots that need attention: at 1.2 miles (Pleasant Green Road): Navigation decision point; at 11.5 miles (US 65): Sharp turn - reduce speed on approach; at 161.4 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
The route from La Monte, MO to St. Louis, MO does not surface many named destination signs beyond the main corridor.
How this page is built
Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from
OSRM
over
OpenStreetMap.
Fuel cost uses
EIA
weekly regional averages.
Pages are published only after passing our data-quality checks; our
methodology page
documents refresh cadence, editorial standards, and known limitations.
