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Trip from Laredo, TX to Missouri City, TX

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 17, 2026 · Editorial standards

Drive Time

5h 51m

Distance

300.6 mi

484 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$45

one way

EV Charging

Unknown

Best Time to Leave

Save up to 39 min
4 AM
5h 39m ★
6 AM
5h 52m
8 AM
6h 18m
10 AM
6h 1m
12 PM
5h 58m
3 PM
6h 2m
5 PM
6h 17m
8 PM
5h 44m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly
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city in and county seat of Webb County, Texas, United States

Laredo, TX

Wikimedia Commons

city in Fort Bend and Harris counties, Texas, United States

Missouri City, TX

Wikimedia Commons

Trip Overview

This 300.6-mile drive from Laredo, TX, to Missouri City, TX, is designed as a single-day adventure, taking approximately 5 hours and 51 minutes. You'll primarily be on US 59, also known as the Lloyd Bentsen Highway and US Highway 59 East, for a significant portion of the journey. With a projected fuel cost of around $45, this route offers a straightforward trip focused on highway travel. Considering its duration and the region, it’s a manageable day trip without the need for an overnight stop. The drive stays within the Great Plains region, offering a consistent landscape as you make your way across Texas.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

150.3 miles from Laredo, TX

A natural place for your longest stop of the day , about 2h 55m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 5h 51m. Total distance: 300.6 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

5h 51m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (76%). Some complex stretches to watch for.

Drive Character

Expect a highway-focused drive for most of this trip, with 76% of the route utilizing major roadways. The longest uninterrupted stretch you'll encounter is 159.7 miles, mainly on US 59. This means you'll experience sustained highway speeds for a considerable part of the journey. While the profile suggests a consistent road experience, keep in mind that the character of US 59 can vary, offering periods of open highway driving. This route emphasizes efficiency and consistent progress rather than varied terrain.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 34 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
US 59 is the longest continuous segment at about 159.7 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on US 59 and Lloyd Bentsen Highway. You will hit about 19 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.3 miles in near San Dario Avenue.

Driving Effort 6/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 300.6 miles you will encounter 19 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 0.3 miles (San Dario Avenue): Navigation decision point; at 179.7 miles (Northwest Zac Lentz Parkway): Exit ramp - move to the correct lane early; at 279.3 miles (I 69; US 59 / Southwest Freeway): Merge point - match speed before joining. Lane positioning matters here.

Critical Maneuvers

5 of 19 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

5
0.3 mi into trip | ~0m in | San Dario Avenue

Turn left onto San Dario Avenue

Navigation decision point

5
179.7 mi into trip | ~3h 28m in | Northwest Zac Lentz Parkway

Take the exit onto Northwest Zac Lentz Parkway

Exit ramp - move to the correct lane early

5
279.3 mi into trip | ~5h 25m in | I 69; US 59 / Southwest Freeway

Merge onto I 69; US 59 / Southwest Freeway

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight right lanes.
8
296 mi into trip | ~5h 44m in

Take the exit toward US 90 Alt: Sugar Land, Stafford

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 112 Toward US 90 Alt: Sugar Land, Stafford
5
296.8 mi into trip | ~5h 45m in

Take the ramp

Lane positioning matters here

Use the straight / right lanes.

Main Roads

Road Distance Duration
US 59 159.7 mi 3h 2m
Lloyd Bentsen Highway 57.6 mi 1h 1m
US Highway 59 East 47.7 mi 53m
Southwest Freeway 16.7 mi 18m
Main Street 3 mi 4m
Clark Boulevard 3 mi 5m
US 59 Northbound Frontage Road 2 mi 4m
West Houston Street 1.6 mi 3m
Longest stretch: US 59 — 159.7 mi, about 3h 2m

Turn-by-Turn Driving Directions

Step-by-step road directions between Laredo, TX and Missouri City, TX.

1

Start on Matamoros Street

0.3 mi · 46 sec · Matamoros Street
2

Turn left onto San Dario Avenue

0.1 mi · 11 sec · San Dario Avenue
3

Continue on San Dario Avenue

0.6 mi · 1 min · San Dario Avenue
4

Turn right onto Park Street

0.3 mi · 34 sec · Park Street
5

Continue on Clark Boulevard

3.0 mi · 5 min · Clark Boulevard
6

Turn left onto Bob Bullock Loop

0.8 mi · 1 min · Bob Bullock Loop
7

Take the ramp

231 ft · 6 sec
8

Merge onto US 59

1.1 mi · 1 min · East Saunders Street
9

Continue on US 59

58 mi · 1 hr 1 min · Lloyd Bentsen Highway
10

Turn left onto US 59

67 mi · 1 hr 18 min · US 59
11

Continue on US 59

1.6 mi · 3 min · West Houston Street
12

Continue on US 59

48 mi · 53 min · US Highway 59 East
13

Take the exit onto Northwest Zac Lentz Parkway

0.5 mi · 1 min · Northwest Zac Lentz Parkway
14

Merge onto US 59; US 77

93 mi · 1 hr 43 min · US 59; US 77
15

Take the exit

0.3 mi · 37 sec
16

Continue on 59 Northbound Frontage Road

1.6 mi · 2 min · 59 Northbound Frontage Road
17

Continue on this road

0.4 mi · 58 sec · this road
18

Continue on US 59 Northbound Frontage Road

2.0 mi · 4 min · US 59 Northbound Frontage Road
19

Continue on Southwest Freeway Frontage Road

1.3 mi · 2 min · Southwest Freeway Frontage Road
20

Take the ramp

0.2 mi · 31 sec
Toward I 69 North, US 59 North
21

Merge onto I 69; US 59

17 mi · 18 min · Southwest Freeway
Use the straight / slight right lanes.
22

Take the exit

0.6 mi · 1 min
Exit 112 Toward US 90 Alt: Sugar Land, Stafford Use the slight right lane.
23

Turn straight onto Southwest Freeway Frontage Road

0.2 mi · 22 sec · Southwest Freeway Frontage Road
Use the straight / right lanes.
24

Take the ramp

0.2 mi · 28 sec
Use the straight / right lanes.
25

Merge onto US 90 Alt

3.0 mi · 4 min · Main Street
Use the left lane.
26

Take the exit

352 ft · 7 sec
Toward FM 2234
27

Continue on this road

397 ft · 8 sec · this road
Toward FM 2234
28

Continue on this road

0.2 mi · 29 sec · this road
Toward FM 2234
29

Continue on this road

351 ft · 8 sec · this road
30

Turn right onto Orchard Street

215 ft · 11 sec · Orchard Street
31

Turn right onto 3rd Street

273 ft · 14 sec · 3rd Street
32

Turn right onto FM 2234

224 ft · 4 sec · Texas Parkway
33

Take the ramp

76 ft · 3 sec
34

Arrive at destination

Trip Plan

To make the most of this 300.6-mile journey, consider an early morning departure from Laredo to avoid potential traffic as you approach the Houston area. With a total duration of nearly six hours, you'll want to plan for at least one stop for fuel and a break. The longest stretch without a major town is 159.7 miles, so ensure your fuel tank is adequately filled before embarking on this segment. Given the highway-focused nature and the single recommended day for this trip, flexibility is key; however, planning your one significant stop around the halfway point can help break up the drive effectively.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 150.3 miles from Laredo, TX, or about 2h 55m into the drive.
The longest continuous stretch on this route runs about 159.7 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 66 miles or 1h 15m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 150.3 miles or 2h 55m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 43m

Traffic, exits, and arrival timing usually matter more near Missouri City, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving Laredo, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Laredo, TX

This is one driving day of about 300.6 miles and 5h 51m.

Your first comfortable stop window is around 66 miles from Laredo, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 59 for about 159.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 150.3 mi from Laredo, TX · 2h 55m into the drive

city in Texas, United States

Mid-route town

Meal stop

Cuero, TX

150 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

San Diego, TX

Fuel and coffee

A short stop after about 66 miles helps settle the day before fatigue starts building.

Refugio, TX

Meal break

The midpoint is around 150.3 miles from Laredo, TX, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before US 59 if your tank is already low. That segment runs about 159.7 miles.

Arriving in Missouri City, TX

The final approach into Missouri City, TX usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Missouri City, TX.

After long uninterrupted mileage, take five minutes before the last urban segment to reset and refocus on exits, merges, and city traffic.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Nearby Places

Restaurants, cafes, gas stations and more along your route.

Main Event Laredo

4.7 ★ ★ ★ ★ ★

Near the start, short detour

3.2 mi from route ~8 min detour $20 to $30

Laredo, Texas

Hours: 11 am–12 pm

+19567222695

Visit website

Imaginarium of South Texas

4.4 ★ ★ ★ ★ ☆

Near the start, right off the route

0.8 mi from route ~2 min detour

Laredo, Texas

Hours: Closed

+19567280404

Visit website

Slaughter Park

4.5 ★ ★ ★ ★ ★

Near the start, short detour

1.5 mi from route ~4 min detour

Laredo, Texas

Hours: 6 am–11 pm

+19567952350

Visit website

20th Century Technology Museum

4.4 ★ ★ ★ ★ ☆

Near the end, short detour

1.5 mi from route ~4 min detour mile 257.7

Wharton, Texas

Hours: 11 am–3 pm

+19794887773

Visit website

Dinosaur Park

4.3 ★ ★ ★ ★ ☆

Near the end, short detour

2.3 mi from route ~6 min detour mile 257.7

Wharton, Texas

+19795322491

Visit website

The Black Cowboy Museum

4.8 ★ ★ ★ ★ ★

Near the end, short detour

3 mi from route ~8 min detour mile 279.1

Rosenberg, Texas

Hours: 10 am–5 pm

+18324516202

Visit website

Riverfront Park

4.2 ★ ★ ★ ★ ☆

Near the end, short detour

2.4 mi from route ~6 min detour mile 257.7

Wharton, Texas

Hours: Open 24 hours

+19795322491

Visit website

Independence Hills Park

4.7 ★ ★ ★ ★ ★

Near the start, ~9 min detour

3.8 mi from route ~9 min detour

Laredo, Texas

Hours: Open 24 hours

Visit website

Escape Again Rooms

4.9 ★ ★ ★ ★ ★

Near the end, ~11 min detour

4.2 mi from route ~11 min detour mile 300.6

Sugar Land, Texas

Hours: 4–10 pm

+18329994572

Visit website

Place data sourced from public business listings. Hours and availability may vary.

Fuel & Cost

Regular Gas

$45.42 one way

$90.84 round trip

$3.84/gal 25.4 MPG avg 105 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.20 $49.72 $99.43
premium $4.54 $53.67 $107.34
diesel $5.61 $66.37 $132.74

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$45

Meals

$25–$50

Total

$70–$95

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 105.2 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $32 in charging · 1 stop · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 90.2 1 $31.56 $14.43
Efficient EV 75.2 0 $26.30 $12.02
EV Truck/SUV 120.2 1 $42.08 $19.24

Gas CO2

105 kg

EV CO2

35 kg (67% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Laredo, TX

Afternoon in Laredo on Friday

Local time

1:52 PM

CDT

Current temp

84°F

Unavailable

Live forecast

Destination

Missouri City, TX

Afternoon in Missouri City on Friday

Local time

1:52 PM

CDT

Current temp

69°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

15 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 51m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Laredo, TX to Missouri City, TX covers 300.6 miles and takes about 5h 51m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are US 59, Lloyd Bentsen Highway, US Highway 59 East. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 150.3 miles from Laredo, TX. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $45.42 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

An early start around 7-8 AM gets you there with plenty of daylight left. A late afternoon start means arriving after dark. Morning is better.

Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

This drive requires moderate attention. Across 300.6 miles you will encounter 19 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

The main spots that need attention: at 0.3 miles (San Dario Avenue): Navigation decision point; at 179.7 miles (Northwest Zac Lentz Parkway): Exit ramp - move to the correct lane early; at 279.3 miles (I 69; US 59 / Southwest Freeway): Merge point - match speed before joining. Lane positioning matters here.

The route from Laredo, TX to Missouri City, TX does not surface many named destination signs beyond the main corridor.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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Return Trip

Missouri City, TX to Laredo, TX

Plan the drive back the other way.

300.8 mi 5h 50m

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