Trip from Los Angeles, CA to Santa Clara, CA
Drive Time
6h 32m
Distance
344.6 mi
Route Type
Turn-heavy local drive
Long day tripTrip Overview
The drive from Los Angeles, CA to Santa Clara, CA covers 344.6 miles and takes about 6h 32m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on North Broadway, US 101 North, Santa Ana Freeway for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $46.81 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
172.3 miles from Los Angeles, CA
A natural place for your longest stop of the day.
Drive Character
Expect a 6h 32m drive with frequent turns across 344.6 miles of local and secondary roads.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| North Broadway | 0 mi | 0m |
| US 101 North | 0 mi | 0m |
| Santa Ana Freeway | 0 mi | 0m |
| Hollywood Freeway | 0 mi | 0m |
| Golden State Freeway | 0 mi | 0m |
| I 5 | 0 mi | 0m |
| Westside Freeway | 0 mi | 0m |
| CA 152 West | 0 mi | 0m |
Step-by-Step Directions
Start on West 1st Street
Turn right onto North Broadway
Take the ramp right toward US 101 North, CA 110
Merge slight left onto Santa Ana Freeway
Continue on Hollywood Freeway
Keep slight left
Merge slight left onto Golden State Freeway
Keep slight left to continue on Golden State Freeway
Keep slight right to continue on I 5 Truck North, CA 14 Truck
Keep slight left
Keep slight left to continue on Golden State Freeway
Keep slight right to continue on Westside Freeway
Take the exit slight right toward CA 152 West: Gilroy, Hollister, San Jose
Continue straight
Keep slight right
Take the exit slight right toward US 101 North: San Jose
Merge slight left onto South Valley Freeway
Keep slight left
Take the exit right toward I 880 South: Los Gatos, Santa Cruz
Merge slight left onto Nimitz Freeway
Take the exit slight right toward Coleman Avenue, Mineta San Jose International Airport
Turn right onto Coleman Avenue
Turn slight left onto CA 82: Santa Clara
Turn straight onto De La Cruz Boulevard
Turn slight right onto Civic Center, El Camino Real
Turn left onto El Camino Real
Turn right onto Lincoln Street
Arrive at your destination
When to Leave
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Drive Plan
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 172.3 miles
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Last hour of driving
Traffic, exits, and arrival timing usually matter more near Santa Clara, CA than in the middle of the route.
Before You Leave
Open the route before leaving Los Angeles, CA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Trip Strategy
Day 1
Settle into the route from Los Angeles, CA
This is one driving day of about 344.6 miles and 6h 32m.
Best Stop Towns on This Route
These towns line up with the pace of this drive and give you clearer places to stop with a purpose.
Late stop town
Meal stop
172 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Travel Advice
Arrival Notes
Seasonal Notes
Stops Along the Way
Halfway Point
Midpoint
About 172.3 mi from Los Angeles, CA
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 172.3 miles from Los Angeles, CA, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions for the drive, so the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| regular | $3.45 | $46.81 | $93.61 |
| midgrade | $3.85 | $52.23 | $104.47 |
| premium | $4.15 | $56.30 | $112.61 |
| diesel | $3.75 | $50.88 | $101.75 |
Based on 25.4 MPG average. Estimated CO2 emission: 120.6 kg one way.
Frequently Asked Questions
More trips from Los Angeles, CA
Los Angeles, CA to Washington, DC
Los Angeles, CA to Houston, TX
Los Angeles, CA to San Antonio, TX
Los Angeles, CA to McKinleyville, CA
Los Angeles, CA to Red Bluff, CA
Los Angeles, CA to Orland, CA
More trips to Santa Clara, CA
Next Route Ideas
Continue From Santa Clara, CA
Explore more options from Los Angeles, CA or browse trips ending in Santa Clara, CA .
Looking for more statewide routes? Browse CA road trips .
Explore maps and details for Los Angeles, CA or Santa Clara, CA on MapSof.net.