Drive Time
4h 8m
Distance
252.5 mi
406 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$38
one way
Photo: Craig Picariello
The drive from Marshfield, MO to Cape Girardeau, MO covers 252.5 miles and takes about 4h 8m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on West Maple Street, South Marshall Street, West Springfield Avenue for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $38.35 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
126.2 miles from Marshfield, MO
A natural place for your longest stop of the day , about 2h 4m into the drive .
Expect a 4h 8m drive with frequent turns across 252.5 miles of local and secondary roads.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Easy - simple navigation with a manageable amount of wheel time
This is a straightforward 4h 8m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Marshfield, MO to Cape Girardeau, MO is straightforward, with well-signed roads and simple exits.
| Road | Distance | Duration |
|---|---|---|
| West Maple Street | Unavailable | Refreshing |
| South Marshall Street | Unavailable | Refreshing |
| West Springfield Avenue | Unavailable | Refreshing |
| North Diggins Main Street | Unavailable | Refreshing |
| US 60 East | Unavailable | Refreshing |
| North Westwood Boulevard | Unavailable | Refreshing |
| I 55 North | Unavailable | Refreshing |
| US 61 | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Step-by-step road directions between Marshfield, MO and Cape Girardeau, MO.
Start on North Clay Street
Turn left onto West Maple Street
Turn right onto South Marshall Street
At the end of the road, turn left
Continue on West Springfield Avenue
Turn right onto North Diggins Main Street
Turn left
Keep slight left to continue on US 60 East: Mountain View, Poplar Bluff
Keep slight right
Turn straight onto North Westwood Boulevard
Turn slight left
Turn left
Take the ramp right
Merge slight left
Take the exit slight right toward I 55 North: Saint Louis
Merge slight left
Keep slight right to continue on US 61, I 55 Business: Cape Girardeau
Turn right onto Shawnee Parkway
Turn left onto South Sprigg Street
Turn right onto Broadway Street
Arrive at your destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 18m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 126.2 miles or 2h 4m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 23m
Traffic, exits, and arrival timing usually matter more near Cape Girardeau, MO than in the middle of the route.
Open the route before leaving Marshfield, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Marshfield, MO
This is one driving day of about 252.5 miles and 4h 8m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 126.2 mi from Marshfield, MO · 2h 4m into the drive
Mid-route town
Meal stop
126 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 126.2 miles from Marshfield, MO, which is a good place for a longer meal and fuel stop.
The final approach into Cape Girardeau, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Cape Girardeau, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$38.35 one way
$76.70 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.25 | $42.28 | $84.56 |
| premium | $4.80 | $47.67 | $95.33 |
| diesel | $5.64 | $56.10 | $112.19 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$38
Meals
$25–$50
Total
$63–$88
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 88.3 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $27 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 75.8 | 0 | $26.51 | $12.12 |
| Efficient EV | 63.1 | 0 | $22.09 | $10.10 |
| EV Truck/SUV | 101 | 1 | $35.35 | $16.16 |
Gas CO2
88 kg
EV CO2
30 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Marshfield on Sunday
Local time
12:09 AM
CDT
Current temp
57°F
Forecast unavailable right now
Destination
Late night in Cape Girardeau on Sunday
Local time
12:09 AM
CDT
Current temp
74°F
Forecast unavailable right now
Along the Route
61°F
Gosnell, AR
126 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Marshfield, MO or browse trips ending in Cape Girardeau, MO.
Looking for more statewide routes? Browse MO road trips.
Explore maps for Marshfield, MO or Cape Girardeau, MO on MapSof.net.
