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Trip from Monroe City, MO to Saint Charles, MO

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 17, 2026 · Editorial standards

Drive Time

1h 55m

Distance

111.5 mi

179 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$17

one way

EV Charging

Unknown

Best Time to Leave

Save up to 25 min
4 AM
1h 47m ★
6 AM
1h 55m
8 AM
2h 12m
10 AM
2h 1m
12 PM
1h 59m
3 PM
2h 2m
5 PM
2h 11m
8 PM
1h 50m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in Marion, Monroe, and Ralls counties, Missouri, United States

Monroe City, MO

Wikimedia Commons

city in and county seat of St. Charles County, Missouri, United States

Saint Charles, MO

Wikimedia Commons

Trip Overview

The drive from Monroe City, MO to Saint Charles, MO covers 111.5 miles and takes about 1h 55m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on 5th Street, US 24 East, Chicago-Kansas City Expressway for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $17.43 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Midpoint

55.7 miles from Monroe City, MO

A natural place for your longest stop of the day , about 57m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 1h 55m. Total distance: 111.5 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

1h 55m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (0%). Straightforward navigation.

Scenic Drive

Turn-heavy local drive route profile.

Drive Character

Expect a 1h 55m drive with frequent turns across 111.5 miles of local and secondary roads.

This route has more turning and local-road decision points than a simple highway run.
There are about 20 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
5th Street is one of the defining roads on this drive.

How Hard Is This Drive?

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. Navigation is very simple - set it and forget it for most of the drive.

Driving Effort 1/10

Very easy - short and simple to drive

Balances navigation complexity with total wheel time.

The drive from Monroe City, MO to Saint Charles, MO is easy. At 1h 55m with 0% highway, most drivers will find it relaxed and low-stress.

Where does it get tricky?

This route does not have any notably tricky sections. Most of the drive from Monroe City, MO to Saint Charles, MO is straightforward, with well-signed roads and simple exits.

Main Roads

Road Distance Duration
5th Street
US 24 East
Chicago-Kansas City Expressway
V
Veterans Road
County Road 422
Paris Gravel Road
Avenue of the Saints

Some road-level metrics are being recalculated.

Longest stretch: 5th Street — detailed segment metrics are refreshing.

Turn-by-Turn Driving Directions

Step-by-step road directions between Monroe City, MO and Saint Charles, MO.

1

Start on North Main Street

0.3 mi · 24 sec · North Main Street
2

Turn right onto 5th Street

1.1 mi · 1 min · 5th Street
3

Turn left

0.4 mi · 34 sec
4

Take the ramp right toward US 24 East, US 36 East, MO 110 East: Hannibal

0.3 mi · 22 sec · US 24 East, US 36 East, MO 110 East: Hannibal
5

Merge slight left onto Chicago-Kansas City Expressway

11 mi · 12 min · Chicago-Kansas City Expressway
6

Continue on V.F.W. Memorial Highway

5.8 mi · 6 min · V.F.W. Memorial Highway
7

Take the exit slight right toward Veterans Road

0.2 mi · 30 sec · Veterans Road
8

Turn right onto Veterans Road

2.1 mi · 3 min · Veterans Road
9

At the end of the road, turn left onto County Road 422

279 ft · 7 sec · County Road 422
10

Continue on Paris Gravel Road

0.5 mi · 1 min · Paris Gravel Road
11

Take the ramp right

121 ft · 3 sec
12

Merge slight left onto Avenue of the Saints

74 mi · 1 hr 27 min · Avenue of the Saints
13

Take the exit slight left toward I 70 East: Saint Louis

0.5 mi · 51 sec · I 70 East: Saint Louis
14

Merge slight left onto Dwight D Eisenhower Highway

17 mi · 21 min · Dwight D Eisenhower Highway
15

Take the exit slight right toward I 70 Business, MO 94: First Capitol Drive, Lewis and Clark Trail

0.1 mi · 14 sec · I 70 Business, MO 94: First Capitol Drive, Lewis and Clark Trail
16

Keep slight left to continue on I 70 Business, MO 94 East: First Capitol Drive, Lindenwood University, SSM Health Saint Joseph Hospital

0.1 mi · 15 sec · I 70 Business, MO 94 East: First Capitol Drive, Lindenwood University, SSM Health Saint Joseph Hospital
17

Turn straight onto First Capitol Drive

0.9 mi · 2 min · First Capitol Drive
18

Turn slight right onto MO 94

0.9 mi · 2 min · MO 94
19

Turn left onto South Second Street

0.3 mi · 57 sec · South Second Street
20

Arrive at your destination

Trip Plan

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 55.7 miles from Monroe City, MO, or about 57m into the drive.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 25 miles or 25m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 55.7 miles or 57m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 1h 34m

Traffic, exits, and arrival timing usually matter more near Saint Charles, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Monroe City, MO so your first major turns are already loaded.

Day 1

Settle into the route from Monroe City, MO

This is one driving day of about 111.5 miles and 1h 55m.

Your first comfortable stop window is around 25 miles from Monroe City, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 55.7 mi from Monroe City, MO · 57m into the drive

city in and county seat of Lincoln County, Missouri, United States

Mid-route town

Meal stop

Troy, MO

56 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Troy, MO to Saint Charles, MO

36.3 mi · 49m

Pacing Suggestions

Bowling Green, MO

Fuel and coffee

A short stop after about 25 miles helps settle the day before fatigue starts building.

Troy, MO

Meal break

The midpoint is around 55.7 miles from Monroe City, MO, which is a good place for a longer meal and fuel stop.

Arriving in Saint Charles, MO

The final approach into Saint Charles, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$17.43 one way

$34.86 round trip

$3.97/gal 25.4 MPG avg 39 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $19.14 $38.28
premium $4.89 $21.46 $42.91
diesel $5.61 $24.62 $49.24

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$17

Meals

$25–$50

Total

$42–$67

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 39 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $12 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 33.4 0 $11.71 $5.35
Efficient EV 27.9 0 $9.76 $4.46
EV Truck/SUV 44.6 0 $15.61 $7.14

Gas CO2

39 kg

EV CO2

13 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Monroe City, MO

Late night in Monroe City on Friday

Local time

4:59 AM

CDT

Current temp

70°F

Unavailable

Live forecast

Destination

Saint Charles, MO

Late night in Saint Charles on Friday

Local time

4:59 AM

CDT

Current temp

57°F

Unavailable

Live forecast

76°F

Troy, MO

56 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

13 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

1h 55m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Monroe City, MO to Saint Charles, MO covers 111.5 miles and takes about 1h 55m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are 5th Street, US 24 East, Chicago-Kansas City Expressway. Expect a mix of highway and local road driving.

This is a comfortable same-day trip.

The midpoint is about 55.7 miles from Monroe City, MO. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $17.43 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.

The drive from Monroe City, MO to Saint Charles, MO is easy. At 1h 55m with 0% highway, most drivers will find it relaxed and low-stress.

This route does not have any notably tricky sections. Most of the drive from Monroe City, MO to Saint Charles, MO is straightforward, with well-signed roads and simple exits.

The route from Monroe City, MO to Saint Charles, MO does not surface many named destination signs beyond the main corridor.

How this page is built

Compiled and maintained by the Trip.ovh planning team at COD Solutions Oy (Helsinki). Each route is built from authoritative open government and mapping datasets rather than crowdsourced reviews. Distances and geometry come from OSRM over OpenStreetMap. Fuel cost uses EIA weekly regional averages. Pages are published only after passing our data-quality checks; our methodology page documents refresh cadence, editorial standards, and known limitations.

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