Drive Time
2h 12m
Distance
113.3 mi
182 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$17
one way
Photo: 大 董
Traveling from Nettleton to Southaven covers 113.3 miles, making for a straightforward 2-hour and 12-minute journey across Mississippi. Because the trip is relatively short, it functions perfectly as a single-day excursion, requiring no overnight stays. You can expect to spend approximately $17 on fuel, depending on your vehicle's efficiency. The route relies primarily on I-22, Goodman Road, and Martin Luther King Drive to navigate the Southeast corridor. Whether you are heading north for business or a change of scenery, this highway-focused drive offers a predictable experience that fits easily into a morning or afternoon schedule.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
0 planned breaks
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
56.6 miles from Nettleton, MS
A natural place for your longest stop of the day , about 1h 4m into the drive .
Expect a high-speed transit experience, as 80% of your time will be spent on highways. The centerpiece of this trip is an 83.7-mile stretch on I-22, which allows you to cover the majority of the distance without frequent stops. Transitioning from the interstate into the local streets of Southaven, such as Goodman Road and Martin Luther King Drive, marks a shift from high-velocity cruising to standard urban driving. The route maintains a consistent, efficient pace throughout the entire 113.3-mile distance. You will find that the road remains steady and focused, prioritizing speed and directness over winding detours.
This is a straightforward highway drive that stays mostly on I 22 and Goodman Road. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 1.2 miles in near US 45; US 278.
Demanding - plan breaks and stay ahead of the key maneuvers
This is a demanding drive. With 15 significant decision points across 113.3 miles, you will need to stay alert — especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 1.2 miles (US 45; US 278): Lane positioning matters here; at 4.9 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 16.2 miles (US 45): Highway fork - watch signs carefully. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn right onto US 45; US 278
Lane positioning matters here
Take the exit toward US 45 North, US 278 West: Tupelo
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Keep slight right at fork onto US 45
Highway fork - watch signs carefully. Lane positioning matters here
Merge onto I 22; US 78
Merge point - match speed before joining. Lane positioning matters here
Keep slight left at fork
Highway fork - watch signs carefully
| Road | Distance | Duration |
|---|---|---|
| I 22 | 83.7 mi | 1h 29m |
| Goodman Road | 8.3 mi | 12m |
| Martin Luther King Drive | 7.7 mi | 8m |
| US 45 | 5.3 mi | 6m |
| Martin Luther King, Junior Drive | 3.3 mi | 4m |
| I 55 | 1.4 mi | 1m |
| Will Robbins Highway | 1 mi | 1m |
| Stateline Road West | 0.4 mi | <1m |
Step-by-step road directions between Nettleton, MS and Southaven, MS.
Start on Main Street
Turn slight right onto MS 145
Turn right onto US 45; US 278
Take the exit
Merge onto US 45; US 278
Continue on US 45; MS 6
Keep slight right at fork onto US 45
Take the exit
Merge onto I 22; US 78
Take the exit
Keep slight left at fork
Turn left onto MS 302
Take the ramp
Merge onto I 55; I 69
Take the exit
Turn left onto Stateline Road West
Turn left onto Millbranch Road
Turn right onto Haleville Drive
Turn left onto Five Oaks Drive North
Arrive at destination
Since this is a quick drive, you have plenty of flexibility regarding your departure time; however, planning around local commuter traffic on the final approach into Southaven is wise. You won't need to worry about extensive rest stops given the short duration, but topping off your tank before leaving Nettleton ensures you stay well within your $17 fuel budget. Keep an eye on your speed as you transition off the long I-22 stretch onto local roads, where speed limits will naturally decrease. Because there are zero required stops on this route, you have the freedom to drive straight through or take a brief break whenever you feel the need to stretch your legs.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 29m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 56.6 miles or 1h 4m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 43m
Traffic, exits, and arrival timing usually matter more near Southaven, MS than in the middle of the route.
Open the route before leaving Nettleton, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Nettleton, MS
This is one driving day of about 113.3 miles and 2h 12m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 56.6 mi from Nettleton, MS · 1h 4m into the drive
Mid-route town
Meal stop
57 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 80 miles helps settle the day before fatigue starts building.
The midpoint is around 56.6 miles from Nettleton, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 22 if your tank is already low. That segment runs about 83.7 miles.
The final approach into Southaven, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Southaven, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$17.32 one way
$34.64 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.26 | $19.00 | $38.00 |
| premium | $4.61 | $20.56 | $41.13 |
| diesel | $5.64 | $25.17 | $50.34 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$17
Meals
$25–$50
Total
$42–$67
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 39.6 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $12 in charging · 0 stops · 68% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 34 | 0 | $11.90 | $5.44 |
| Efficient EV | 28.3 | 0 | $9.91 | $4.53 |
| EV Truck/SUV | 45.3 | 0 | $15.86 | $7.25 |
Gas CO2
40 kg
EV CO2
13 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Nettleton on Sunday
Local time
5:06 AM
CDT
Current temp
64°F
Forecast unavailable right now
Destination
Late night in Southaven on Sunday
Local time
5:06 AM
CDT
Current temp
64°F
Forecast unavailable right now
Along the Route
64°F
Collierville, TN
57 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
Both ends of the route are sitting at about the same temperature right now.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
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