Origin
North La Crosse, WI
Night in North La Crosse on Wednesday
Local time
11:27 PM
CDT
Current temp
66°F
Unavailable
Last recalculated Apr 16, 2026
Drive Time
3h 19m
Distance
149 mi
240 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$23
one way
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
North La Crosse, WI
Wikimedia Commons
Winneconne, WI
Tom Fisk
This 149-mile drive from North La Crosse, WI to Winneconne, WI takes approximately 3 hours and 19 minutes, making it a manageable one-day trip. You'll primarily travel on State Highway 21, I-90, and US 53, with 91% of the journey on highways. Budget around $23 for fuel. The route offers a straightforward Midwest journey, connecting two points within Wisconsin without significant regional shifts. It’s a practical option for a direct trip with minimal fuss.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
74.5 miles from North La Crosse, WI
A natural place for your longest stop of the day , about 1h 27m into the drive .
Expect a highway-focused experience for most of this 149-mile route, with 91% of your travel occurring on major roads like State Highway 21, I-90, and US 53. The longest uninterrupted stretch you'll encounter is 65.4 miles, primarily on State Highway 21, offering a solid period of consistent driving. This profile suggests a drive that is largely efficient, allowing you to cover ground steadily without frequent turns or significant slowdowns through towns. It's geared towards getting you to your destination with minimal detours.
This is a straightforward highway drive that stays mostly on State Highway 21 and I 90. Navigation is very simple - set it and forget it for most of the drive. The trickiest moment comes around 1.2 miles in near US 53.
Very easy - short and simple to drive
The drive from North La Crosse, WI to Winneconne, WI is easy. At 3h 19m with 91% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
The main spots that need attention: at 1.2 miles (US 53): Exit ramp - move to the correct lane early; at 59.6 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 59.8 miles: Highway fork - watch signs carefully.
These are the spots where you need to pay the most attention. Preview them before you drive.
Take the exit onto US 53
Exit ramp - move to the correct lane early
Take the exit toward WI 80: Necedah, New Lisbon
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Keep slight left at fork
Highway fork - watch signs carefully
At end of road, turn left onto WI 80 / State Highway 80
Navigation decision point
Turn left onto WI 21; WI 22 / South Cambridge Street
Navigation decision point
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from North La Crosse, WI to Winneconne, WI, road signs begin pointing toward New Lisbon along the way.
New Lisbon
| Road | Distance | Duration |
|---|---|---|
| State Highway 21 | 65.4 mi | 1h 31m |
| I 90 | 44.4 mi | 47m |
| US 53 | 14 mi | 15m |
| State Highway 80 | 9.6 mi | 13m |
| Willow Street | 3.5 mi | 6m |
| West Main Street | 2.5 mi | 6m |
| State Highway 116 | 1.7 mi | 2m |
| Bannerman Avenue | 1.6 mi | 4m |
Step-by-step road directions between North La Crosse, WI and Winneconne, WI.
Start on US 53; CTH B
Take the exit onto US 53
Continue on I 90
Take the exit
Keep slight left at fork
Turn left onto WI 80
Continue on WI 80
At end of road, turn left onto WI 80
Continue on WI 80
Turn right onto WI 21
Continue on WI 21
Continue on WI 21
Continue on WI 21
Turn left onto WI 21; WI 22
Turn right onto WI 21; WI 22; WI 73
Continue on WI 21; WI 73
Continue on WI 21; CTH EE
Continue on WI 21
Continue on WI 21
Continue on WI 116; CTH F
Continue on WI 116
Continue on WI 116
Continue on WI 116
Continue on WI 116; CTH B
Continue on WI 116
Arrive at destination
Given its 3-hour duration, this 149-mile trip is easily completed in a single day. Consider an early morning departure to maximize your time at your destination or simply to avoid any potential midday traffic. With only one recommended stop and a fuel cost of about $23, planning is straightforward. The longest stretch of 65.4 miles on State Highway 21 means you can settle in for a good portion of the drive. Keep an eye on your fuel gauge, as highway stretches can sometimes be farther apart than they appear.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 33 miles or 37m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 74.5 miles or 1h 27m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 37m
Traffic, exits, and arrival timing usually matter more near Winneconne, WI than in the middle of the route.
Open the route before leaving North La Crosse, WI so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from North La Crosse, WI
This is one driving day of about 149 miles and 3h 19m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 74.5 mi from North La Crosse, WI · 1h 27m into the drive
Mid-route town
Meal stop
75 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 33 miles helps settle the day before fatigue starts building.
The midpoint is around 74.5 miles from North La Crosse, WI, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before State Highway 21 if your tank is already low. That segment runs about 65.4 miles.
The final approach into Winneconne, WI usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Winneconne, WI.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$23.29 one way
$46.59 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $25.58 | $51.15 |
| premium | $4.89 | $28.67 | $57.35 |
| diesel | $5.61 | $32.90 | $65.79 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$23
Meals
$25–$50
Total
$48–$73
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 52.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $16 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 44.7 | 0 | $15.64 | $7.15 |
| Efficient EV | 37.3 | 0 | $13.04 | $5.96 |
| EV Truck/SUV | 59.6 | 0 | $20.86 | $9.54 |
Gas CO2
52 kg
EV CO2
17 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Night in North La Crosse on Wednesday
Local time
11:27 PM
CDT
Current temp
66°F
Unavailable
Destination
Night in Winneconne on Wednesday
Local time
11:27 PM
CDT
Current temp
43°F
Unavailable
64°F
Adams, WI
75 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from North La Crosse, WI or browse trips ending in Winneconne, WI.
Looking for more statewide routes? Browse WI road trips.
Explore maps for North La Crosse, WI or Winneconne, WI on MapSof.net.