Drive Time
5h 19m
Distance
325.2 mi
523 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$50
one way
Photo: 大 董
The drive from Oxford, MS to Biloxi, MS covers 325.2 miles and takes about 5h 19m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Courthouse Square, South Lamar Boulevard, University Avenue for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $49.71 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
162.6 miles from Oxford, MS
A natural place for your longest stop of the day , about 2h 39m into the drive .
Expect a 5h 19m drive with frequent turns across 325.2 miles of local and secondary roads.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Easy - simple navigation with a manageable amount of wheel time
This is a straightforward 5h 19m drive. You will face about 0 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Oxford, MS to Biloxi, MS is straightforward, with well-signed roads and simple exits.
| Road | Distance | Duration |
|---|---|---|
| Courthouse Square | Unavailable | Refreshing |
| South Lamar Boulevard | Unavailable | Refreshing |
| University Avenue | Unavailable | Refreshing |
| MS 7 South | Unavailable | Refreshing |
| I 20 East | Unavailable | Refreshing |
| Richland | Unavailable | Refreshing |
| Highway 49 South | Unavailable | Refreshing |
| I 59 South | Unavailable | Refreshing |
Per-road distance and duration are being refreshed from OSRM for this route.
Step-by-step road directions between Oxford, MS and Biloxi, MS.
Start on Courthouse Square
Continue on Courthouse Square
Turn right
Turn right onto South Lamar Boulevard
Turn left onto University Avenue
Enter the roundabout and take exit 1 toward University Avenue
Exit the rotary
Merge slight left
Enter the roundabout and take exit 1 toward MS 7 South: Water Valley
Exit the roundabout onto MS 7 South: Water Valley
Take the exit slight left
Continue straight
Take the exit slight right toward I 20 East, US 49 South: Meridian, Hattiesburg
Keep slight right to continue on Richland, Hattiesburg
Merge slight left onto Highway 49 South
Continue straight
Continue straight
Take the exit slight right toward I 59 South: New Orleans, Gulf Coast
Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway
Take the exit slight right toward US 98 East: Lucedale, Mobile
Take the exit slight right toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Keep slight left to continue on Multi Purpose Center, Hattiesburg
Turn right
Take the exit slight right toward MS 67 South: D'Iberville, Biloxi
Continue on Biloxi-D'Iberville Scenic Expressway
Continue straight
Take the exit slight right toward Division Street
Turn left onto Division Street
Turn right onto Main Street
Turn left onto Howard Avenue
Arrive at your destination
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 18m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 162.6 miles or 2h 39m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 22m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Open the route before leaving Oxford, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Oxford, MS
This is one driving day of about 325.2 miles and 5h 19m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 162.6 mi from Oxford, MS · 2h 39m into the drive
Mid-route town
Meal stop
163 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
The final approach into Biloxi, MS usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Biloxi, MS.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$49.71 one way
$99.43 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.26 | $54.53 | $109.06 |
| premium | $4.61 | $59.02 | $118.05 |
| diesel | $5.64 | $72.25 | $144.50 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$50
Meals
$25–$50
Total
$75–$100
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 113.8 kg one way. Prices: EIA weekly data, 2026-04-06.
Driving Electric?
About $34 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 97.6 | 1 | $34.15 | $15.61 |
| Efficient EV | 81.3 | 0 | $28.46 | $13.01 |
| EV Truck/SUV | 130.1 | 1 | $45.53 | $20.81 |
Gas CO2
114 kg
EV CO2
38 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive. If you're planning ahead, check the forecast closer to your travel date.
Origin
Late night in Oxford on Sunday
Local time
2:33 AM
CDT
Current temp
63°F
Forecast unavailable right now
Destination
Late night in Biloxi on Sunday
Local time
2:33 AM
CDT
Current temp
69°F
Forecast unavailable right now
Along the Route
85°F
Magee, MS
163 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
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