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Trip from Pamplico, SC to Mount Pleasant, SC

Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 17, 2026 · Editorial standards

Drive Time

2h 27m

Distance

97.7 mi

157 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$15

one way

EV Charging

Unknown

Best Time to Leave

Save up to 30 min
4 AM
2h 18m ★
6 AM
2h 28m
8 AM
2h 48m
10 AM
2h 35m
12 PM
2h 33m
3 PM
2h 36m
5 PM
2h 47m
8 PM
2h 22m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Pamplico, SC, SC

Pamplico, SC

대정 김

town in Charleston County, South Carolina, United States

Mount Pleasant, SC

Wikimedia Commons

Trip Overview

The drive from Pamplico, SC to Mount Pleasant, SC covers 97.7 miles and takes about 2h 27m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on SC 41, County Line Road, State Highway 41 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 47.8 miles on SC 41. At current regular gas prices, budget about $15.28 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Midpoint

48.8 miles from Pamplico, SC

A natural place for your longest stop of the day , about 1h 14m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 2h 27m. Total distance: 97.7 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

2h 27m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (66%). Some complex stretches to watch for.

Drive Character

This is a 2h 27m highway drive covering 97.7 miles, with most of the trip on SC 41 and County Line Road. The longest continuous stretch is about 47.8 miles on SC 41.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 22 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
SC 41 is the longest continuous segment at about 47.8 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on SC 41 and County Line Road. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near SC 51 / North Pamplico Highway.

Driving Effort 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 97.7 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: near the start (SC 51 / North Pamplico Highway): Sharp turn - reduce speed on approach; at 8.7 miles (US 378): Navigation decision point; at 85.8 miles (SC 41): Lane positioning matters here.

Critical Maneuvers

5 of 10 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

6
0 mi into trip | ~0m in | SC 51 / North Pamplico Highway

Turn sharp left onto SC 51 / North Pamplico Highway

Sharp turn - reduce speed on approach

4
8.7 mi into trip | ~15m in | US 378

Turn left onto US 378

Navigation decision point

6
85.8 mi into trip | ~2h 7m in | SC 41

At end of road, turn left onto SC 41

Lane positioning matters here

Use the straight lane.
5
91.5 mi into trip | ~2h 16m in | US 17

Merge onto US 17

Merge point - match speed before joining. Lane positioning matters here

Use the left lane.
5
97.6 mi into trip | ~2h 27m in

Turn left

Navigation decision point

Main Roads

Road Distance Duration
SC 41 47.8 mi 1h 10m
County Line Road 13.7 mi 18m
State Highway 41 8.2 mi 12m
South Pamplico Highway 8 mi 14m
US 17 4.3 mi 7m
Kingsburg Highway 3.8 mi 5m
US 378 3.5 mi 4m
North Georgetown Highway 3.1 mi 5m
Longest stretch: SC 41 — 47.8 mi, about 1h 10m

Turn-by-Turn Driving Directions

Step-by-step road directions between Pamplico, SC and Mount Pleasant, SC.

1

Start on State Road S-21-132

40 ft · 8 sec · North Walnut Street
2

Continue on North Walnut Street

75 ft · 11 sec · North Walnut Street
3

Turn sharp left onto SC 51

84 ft · 1 sec · North Pamplico Highway
4

Continue on SC 51

0.6 mi · 1 min · South Walnut Street
5

Continue on SC 51

8.0 mi · 14 min · South Pamplico Highway
6

Turn left onto US 378

3.5 mi · 4 min · US 378
7

Turn right onto Kingsburg Highway

3.8 mi · 5 min · Kingsburg Highway
8

Continue on SC 41; SC 51

3.1 mi · 5 min · North Georgetown Highway
9

Continue on SC 41; SC 51

2.6 mi · 4 min · North Main Street
10

Continue on SC 41; SC 51

8.2 mi · 12 min · State Highway 41
11

Continue on SC 41; SC 51

14 mi · 18 min · County Line Road
12

Turn slight right onto SC 41

42 mi · 1 hr · SC 41
13

At end of road, turn left onto SC 41

0.8 mi · 1 min · SC 41
Use the straight lane.
14

Continue on SC 41

4.7 mi · 7 min · SC 41
Use the straight lane.
15

Take the ramp

0.1 mi · 18 sec
16

Merge onto US 17

4.3 mi · 7 min · US 17
Use the left lane.
17

Take the exit

0.2 mi · 24 sec
Toward I 526 Business East: Chuck Dawley Boulevard
18

Merge onto I 526 Bus

0.3 mi · 26 sec · Mark Clark Expressway
19

Continue on I 526 Bus

1.3 mi · 2 min · Chuck Dawley Boulevard
20

Turn right onto SC 703

237 ft · 12 sec · Coleman Boulevard
21

Turn left

76 ft · 5 sec
22

Arrive at destination

Trip Plan

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 48.8 miles from Pamplico, SC, or about 1h 14m into the drive.
The longest continuous stretch on this route runs about 47.8 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 21 miles or 34m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 48.8 miles or 1h 14m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 1h 59m

Traffic, exits, and arrival timing usually matter more near Mount Pleasant, SC than in the middle of the route.

Before You Leave

+

Open the route before leaving Pamplico, SC so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Pamplico, SC

This is one driving day of about 97.7 miles and 2h 27m.

Your first comfortable stop window is around 21 miles from Pamplico, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on SC 41 for about 47.8 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 48.8 mi from Pamplico, SC · 1h 14m into the drive

town in Georgetown County, South Carolina, United States

Mid-route town

Meal stop

Andrews, SC

49 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Andrews, SC

Fuel and coffee

A short stop after about 21 miles helps settle the day before fatigue starts building.

Andrews, SC

Meal break

The midpoint is around 48.8 miles from Pamplico, SC, which is a good place for a longer meal and fuel stop.

Arriving in Mount Pleasant, SC

The final approach into Mount Pleasant, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Mount Pleasant, SC.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$15.28 one way

$30.56 round trip

$3.97/gal 25.4 MPG avg 34 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.34 $16.71 $33.41
premium $4.70 $18.08 $36.16
diesel $5.61 $21.57 $43.14

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$15

Meals

$25–$50

Total

$40–$65

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 34.2 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $10 in charging · 0 stops · 68% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 29.3 0 $10.26 $4.69
Efficient EV 24.4 0 $8.55 $3.91
EV Truck/SUV 39.1 0 $13.68 $6.25

Gas CO2

34 kg

EV CO2

11 kg (68% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Pamplico, SC

Afternoon in Pamplico on Friday

Local time

4:13 PM

EDT

Current temp

49°F

Unavailable

Live forecast

Destination

Mount Pleasant, SC

Afternoon in Mount Pleasant on Friday

Local time

4:13 PM

EDT

Current temp

59°F

Unavailable

Live forecast

49°F

Andrews, SC

49 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

10 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 27m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Pamplico, SC to Mount Pleasant, SC covers 97.7 miles and takes about 2h 27m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.

The main roads are SC 41, County Line Road, State Highway 41. Most of the drive stays on highways, so watch for ramps and exits.

This is a comfortable same-day trip.

The midpoint is about 48.8 miles from Pamplico, SC. Look for rest areas, gas stations, or food options near the halfway mark.

At current regular gas prices, expect to spend about $15.28 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.

Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.

This drive requires moderate attention. Across 97.7 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

The main spots that need attention: near the start (SC 51 / North Pamplico Highway): Sharp turn - reduce speed on approach; at 8.7 miles (US 378): Navigation decision point; at 85.8 miles (SC 41): Lane positioning matters here.

The route from Pamplico, SC to Mount Pleasant, SC does not surface many named destination signs beyond the main corridor.

How this page is built

Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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