Origin
Pamplico, SC
Afternoon in Pamplico on Friday
Local time
4:13 PM
EDT
Current temp
49°F
Unavailable
Compiled and reviewed by the Trip.ovh planning team at COD Solutions Oy · Last reviewed Apr 17, 2026 · Editorial standards
Drive Time
2h 27m
Distance
97.7 mi
157 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$15
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Pamplico, SC
대정 김
Mount Pleasant, SC
Wikimedia Commons
The drive from Pamplico, SC to Mount Pleasant, SC covers 97.7 miles and takes about 2h 27m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on SC 41, County Line Road, State Highway 41 for much of the mileage, and the overall profile is highway-focused drive. The longest uninterrupted segment is about 47.8 miles on SC 41. At current regular gas prices, budget about $15.28 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
48.8 miles from Pamplico, SC
A natural place for your longest stop of the day , about 1h 14m into the drive .
Weekend Trip
Doable as a same-day drive at 2h 27m. Total distance: 97.7 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 27m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (66%). Some complex stretches to watch for.
This is a 2h 27m highway drive covering 97.7 miles, with most of the trip on SC 41 and County Line Road. The longest continuous stretch is about 47.8 miles on SC 41.
This is a straightforward highway drive that stays mostly on SC 41 and County Line Road. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near SC 51 / North Pamplico Highway.
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 97.7 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (SC 51 / North Pamplico Highway): Sharp turn - reduce speed on approach; at 8.7 miles (US 378): Navigation decision point; at 85.8 miles (SC 41): Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn sharp left onto SC 51 / North Pamplico Highway
Sharp turn - reduce speed on approach
Turn left onto US 378
Navigation decision point
At end of road, turn left onto SC 41
Lane positioning matters here
Merge onto US 17
Merge point - match speed before joining. Lane positioning matters here
Turn left
Navigation decision point
| Road | Distance | Duration |
|---|---|---|
| SC 41 | 47.8 mi | 1h 10m |
| County Line Road | 13.7 mi | 18m |
| State Highway 41 | 8.2 mi | 12m |
| South Pamplico Highway | 8 mi | 14m |
| US 17 | 4.3 mi | 7m |
| Kingsburg Highway | 3.8 mi | 5m |
| US 378 | 3.5 mi | 4m |
| North Georgetown Highway | 3.1 mi | 5m |
Step-by-step road directions between Pamplico, SC and Mount Pleasant, SC.
Start on State Road S-21-132
Continue on North Walnut Street
Turn sharp left onto SC 51
Continue on SC 51
Continue on SC 51
Turn left onto US 378
Turn right onto Kingsburg Highway
Continue on SC 41; SC 51
Continue on SC 41; SC 51
Continue on SC 41; SC 51
Continue on SC 41; SC 51
Turn slight right onto SC 41
At end of road, turn left onto SC 41
Continue on SC 41
Take the ramp
Merge onto US 17
Take the exit
Merge onto I 526 Bus
Continue on I 526 Bus
Turn right onto SC 703
Turn left
Arrive at destination
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 21 miles or 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 48.8 miles or 1h 14m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 59m
Traffic, exits, and arrival timing usually matter more near Mount Pleasant, SC than in the middle of the route.
Open the route before leaving Pamplico, SC so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Pamplico, SC
This is one driving day of about 97.7 miles and 2h 27m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 48.8 mi from Pamplico, SC · 1h 14m into the drive
Mid-route town
Meal stop
49 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 21 miles helps settle the day before fatigue starts building.
The midpoint is around 48.8 miles from Pamplico, SC, which is a good place for a longer meal and fuel stop.
The final approach into Mount Pleasant, SC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Mount Pleasant, SC.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$15.28 one way
$30.56 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.34 | $16.71 | $33.41 |
| premium | $4.70 | $18.08 | $36.16 |
| diesel | $5.61 | $21.57 | $43.14 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$15
Meals
$25–$50
Total
$40–$65
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 34.2 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $10 in charging · 0 stops · 68% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 29.3 | 0 | $10.26 | $4.69 |
| Efficient EV | 24.4 | 0 | $8.55 | $3.91 |
| EV Truck/SUV | 39.1 | 0 | $13.68 | $6.25 |
Gas CO2
34 kg
EV CO2
11 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Pamplico on Friday
Local time
4:13 PM
EDT
Current temp
49°F
Unavailable
Destination
Afternoon in Mount Pleasant on Friday
Local time
4:13 PM
EDT
Current temp
59°F
Unavailable
49°F
Andrews, SC
49 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Compiled by the Trip.ovh planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Pamplico, SC or browse trips ending in Mount Pleasant, SC.
Looking for more statewide routes? Browse SC road trips.